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| 1 | Low-grade gliomas:do changes in rCBV measurements at longitudinal perfusion-weighted MR imaging predict malignant transformation?显示文摘Radiology. 2008 Apr;247(1):170-8.PURPOSE: To prospectively perform longitudinal magnetic resonance (MR) perfusion imaging of conservatively treated low-gradegliomas to determine whether relative cerebral blood volume (rCBV) changes precede malignant transformation as defined | Danchaivijitr N Waldman AD Tozer DJ Benton CE Brasil Caseiras G Tofts PS Rees JH J?ger HR | 2008 | 中国神经肿瘤杂志2008，6，2： | 7 |
| 2 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013，19，48： | 4 |
| 3 | Guidelines for resection of colorectal cancer liver metastases 显示文摘 | Garden O J Rees M Poston G J | 2006 | Gut2006，55，3： | 1 |
| 4 | A tran sient two-dimensional finite volume model for the simulation of vertical U-tube ground heat exchanges 显示文摘 | YAVUZTURK C SPLITLER J D REES S J | 1999 | ASHRAE Transactions1999，105，2： | 1 |
| 5 | Animal models of diabetes mellitus 显示文摘 | Rees D A Alcolado J C | 2005 | Diabet Med2005，22，4： | 1 |
| 6 | Thermal decomposition of RDX and mixtures显示文摘 | Hussian G Rees G J | 1995 | Fuel1995，74，2： | 1 |
| 7 | Turbine blade fir-tree root design optimization using intelligent CAD and finite element analysis 显示文摘 | Song W Keane A Rees J | 2002 | Computer and Structure2002，80，： | 1 |
| 8 | Microemulsion-based media as novel drug delivery systems 显示文摘 | Lawrence M J Rees G D | 2000 | Advanced Drug Delivery Reviews2000，45，1： | 1 |
| 9 | The Stability of Lactic Acid Production in Resting Suspensions of Lactobacillus Delbrueeckii显示文摘 | REES J F PIRT S J | 1979 | Journal of Chemical Technology and Biotechnology1979，29，9： | 1 |
| 10 | Microemulsion-based media as novel drug delivery systems显示文摘 | LAWRENCE M J REES G D | 2000 | Adv Drug Deliv Rev2000，45，： | 1 |
| 11 | Multiplanar reconstructed computed tomography images improves depiction and understanding of the anatomy of the frontal sinus and recess显示文摘 | Kew J Rees GL Close D | 2002 | Am J Rhinol2002，16，2： | 1 |
| 12 | Temporal variability of denitrification in estuarine sediments显示文摘 | LAW C S REES A P OWENS N J P | 1991 | Estuarine Coastal and Shelf Science1991，33，1： | 1 |
| 13 | The Effect of niobium in solid solution on the transformation kinetics of bainite 显示文摘 | Perdrix J Maurickx T | 1995 | Mater Sci Eng A1995，194，： | 1 |
| 14 | One-pot synthesis of tetrasubstituted pyrazoles-proof of regiochemistry 显示文摘 | HANEFELD U REES C W WHITE A J P | 1996 | J Chem Soc Perkin Trans 11996，13，： | 1 |
| 15 | Effects of the substrate to chamber wall distance on the structure and properties of CrAlN films deposited by pulsed-closed field unbalanced magnetron sputtering (P-CFUBMS) 显示文摘 | L1N J MISHRA B MOORE J J SPROUL W D REES J A | 2007 | Surface and Coatings Technology2007，201，1617： | 1 |
| 16 | Mustard gas casual ties显示文摘 | REES J HARPER P ELLIS F | 1991 | The Lancet1991，337，： | 1 |
| 17 | Filtration increases the correlation between water extractable organic carbon and soil microbial activity显示文摘 | REES R M PARKER J P | 2005 | Soil Biology & Biochemistry2005，37，： | 1 |
| 18 | Cross-reactivity of IgE antibodies to allergens显示文摘 | Aalberse RC Akkerdaas J Van Ree R | 2001 | Allergy2001，56，6： | 1 |
| 19 | Medium-vacuum centrifugal molecular distillation in the isolation of high-boiling and heat-sensitive compounds,Part Ⅱ Petroleum residus显示文摘 | Rees G J | 1975 | Vacuum1975，25，9： | 1 |
| 20 | The effect of temperature and relative humidity on population growth of three Liposcelis species (Psocoptera:Liposcelidae) infesting stored products in tropical countries显示文摘 | Rees D P and Walker A J | 1990 | Bulletin of Entomological esearch1990，，80： | 1 |
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