|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 2 | Critical velocity and burning rate in pool fire during longitudinal ventilation显示文摘 | JAE S R HING S R DONG H K | 2007 | Tunnelling and Underground Space Technology2007，，22： | 1 |
| 3 | Targeted delivery of low moleculardrugs using chitosan and its derivatives显示文摘 | Jae H P Gurusamy S Kwangmeyung K | 2010 | Advanced Drug Delivery Revie-ws2010，62，： | 1 |
| 4 | Improved method for efficient production of biodiesel from palm oil显示文摘 | RAHMAN TALUKDER M M MIN BEATRICE K L PUAY SONG O PUAH S CHUAN WU J JAE WON C CHOW Y | 2008 | Energy Fuels2008，22，1： | 1 |
| 5 | Lack of association between vitamin D receptor genotypes and osteoporosis in Korean显示文摘 | Sung K L Young S P Jae M P | 1995 | J Clin Endocrinol Metab1995，80，12： | 1 |
| 6 | A new process for the synthesis of diphenyl carbonate from dimethyl carbonate and phenol over heterogeneous catalysts显示文摘 | Won B K Jae S L | 1999 | Catalyst Letter1999，59，1： | 1 |
| 7 | Enhancement of radiation effects by combined docetaxel and flavopiridol treatment in lung cancer cells 显示文摘 | Jae - Chul K Debabrata S Cao QW | 2004 | Radiotherapy and Oncology2004，71，2： | 1 |
| 8 | Current status and per- spectives of biopharmaceutical drugs 显示文摘 | JAE K R HYO S K DOO H N | 2012 | Biotechnology and Bioprocess Engineering2012，17，： | 1 |
| 9 | The relationship between cytokines and HPV - 16 ,HPV - 16 E6,E7 and high - risk HPV viral load in the uterine cervix显示文摘 | Seung H S Jae K L O ye S S | 2007 | Gynecol O ncol2007，104，3： | 1 |
| 10 | The inverse associationbetween cardiorespiratory fitness and C-reactive protein is mediatedby autonomic function:a possible role of the cholinergic antiin-flammatory pathway显示文摘 | Jae S Y Heffernan K S Yoon E S | 2009 | Mol Med2009，15，910： | 1 |
| 11 | Influence of aggregatesize on the compressive size effect according to differentconcrete types 显示文摘 | JAE I S KEUN H Y JOONG K J | 2013 | Construction and Building Materials2013，，44： | 1 |
| 12 | Charge pump with perfect current matching characteristics in phaselocked loops显示文摘 | Jae S L Min S K Shin I L | 2000 | Electronics Letters2000，36，23： | 1 |
| 13 | Highly transparent sapphire micro-grating structures with large diffuse light scattering显示文摘 | YEONG H K JAE S Y | 2011 | Opt Express2011，19，15： | 1 |
| 14 | A case study for determining standard time in a multi-pattern and short life-cycle production system显示文摘 | Chang S K Myung S C Jae J R | 2007 | Computers&Industrial Engineering2007，53，： | 1 |
| 15 | Capsular block syndrome after cata- ract surgery:clinic analysis and classification显示文摘 | Hong Kyum K Jae Pil S | 2008 | J Cataract Re- fract Surg2008，34，： | 1 |
| 16 | Study on macrophage activation and structural characteristics of purified polysaccharides from the liquid culture broth of Hericium erinaceus显示文摘 | Jong S L Jae Y C Eock K H | 2009 | Carbo Poly2009，78，1： | 1 |
| 17 | On determining minimal spectrally arbitrary patterns 显示文摘 | Cavers M S Kim In - Jae Shader B L Vander Meulen K N | 2005 | Electronic Journal of Linear Algebra2005，13，： | 1 |
| 18 | Acute aortic syndromes and thoracic aortic aneurysm显示文摘 | Vijay S Ramznath M Jae K | 2009 | Mayo Clinic Proceedings2009，，5： | 1 |
| 19 | Granuloeyte stimulating factor attenuates hypoxie-ischemie brain injury by inhibit in apoptosis in neonatal rats显示文摘 | Bong R K Jae W S Dong K S | 2008 | Yonsei Med2008，49，5： | 1 |
| 20 | Modification of Mg2Si morphology in squeeze cast Mg-Al-Zn-Si alloys by Ca or Paddition显示文摘 | JAE JOONG KIM DO HYANG KIM SHIN K S | 1999 | Scripta Materialia1999，41，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员