|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Oxygen radical formation does not have an impact in the treatment of severe acute experimental pancreatitis using free cellular hemoglobin显示文摘瞄准:Microcirculatory 机能障碍和免费的氧激进分子是在严重尖锐胰腺炎的致病的重要因素。另外的氧交货可能每氧化提高类脂化合物,但是可以也改进胰腺的微循环。这研究在严重尖锐胰腺炎的一个啮齿类动物模型在氧激进分子和微循环的形成上估计免费细胞的牛的血红素的效果。方法:在尖锐胰腺炎 Wistar 老鼠的正式就职以后的十五分钟收到了任何一个 0.8 mL 牛的血红素(HBOC-200 ) , hydroxyethyl 淀粉(HES ) 或保证血量正常替换的生理盐水的 2.4 mL。在检查的 6 h 以后,胰每氧化产品 malondialdehyde (MDA ) 为类脂化合物的间接测量被切除并且很快处理了并且在胰腺的织物减少了谷胱甘肽(GSH ) 。结果:HBOC-200 的单个申请改进了胰腺的微循环并且显著地减少了组织病理学说的织物损坏。MDA 的织物集中没在这些组之间不同。另外,在 GSH 层次的差别都没被检测。结论:不过 HBOC-200 和 HES 的单个申请改进胰腺的微循环,在类脂化合物的没有差别每氧化,产品被检测。另外的氧供应(HBOC-200 ) 的有益的效果不每氧化导致提高的类脂化合物。 | Helge Kleinhans Oliver Mann Paulus G Schurr Jussuf T Kaifi Bente Hansen Jakob R Izbicki Tim Strate | 2006 | World Journal of Gastroenterology2006，12，18： | 6 |
| 2 | Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy显示文摘AIM: To study the prognostic value of adjuvant chemo-therapy in patients with pancreatic, ductal adenocar-cinoma.METHODS: Lymph nodes from 106 patients with resectable pancreatic ductal adenocarcinoma were systematically sampled. A total of 318 lymph nodes classified histopathologically as tumor-free were examined using sensitive immunohistochemical assays. Forty-three (41%) of the 106 patients were staged as pT1/2, 63 (59%) as pT3/4, 51 (48%) as pN0, and 55 (52%) as pN1. The study population included 59 (56%) patients exhibiting G1/2, and 47 (44%) patients with G3 tumors. Patients received no adjuvant chemo- or radiation therapy and were followed up for a median of 12 (range: 3.5 to 139) mo.RESULTS: Immunostaining with Ber-EP4 revealed nodal microinvolvement in lymph nodes classified as “tumor free” by conventional histopathology in 73 (69%) out of the 106 patients. Twenty-nine (57%)of 51 patients staged histopathologically as pN0 had nodal microinvolvement. The five-year survival probability for pN0-patients was 54% for those without nodal microinvolvement and 0% for those with nodal microinvolvement. Cox-regression modeling revealed the independent prognostic effect of nodal microinvolvement on recurrence-free (relative risk 2.92, P = 0.005) and overall (relative risk 2.49, P = 0.009) survival.CONCLUSION: The study reveals strong and independent prognostic significance of nodal microinvolvement in patients with pancreatic ductal adenocarcinoma who have received no adjuvant therapy. The addition of immunohistochemical findings to histopathology reports may help to improve risk stratification of patients with pancreatic cancer. | Emre F Yekebas Dean Bogoevski Michael Bubenheim Bjrn-Christian Link Jussuf T Kaifi Robin Wachowiak Oliver Mann Asad Kutup Guellue Cataldegirmen Lars Wolfram Andreas Erbersdobler Christoph Klein Klaus Pantel Jakob R Izbicki | 2006 | World Journal of Gastroenterology2006，12，40： | 3 |
| 3 | 显示文摘 | Jakob T WalkeT PS Krieg AM | 1998 | J Immunol1998，161，6： | 1 |
| 4 | Photodynamic therapy for palliation of nonresectable bile duct cancer-preliminary results with a new diode laser system显示文摘 | Zoepf T Jakobs R Arnold JC | 2001 | Am J Gastroenterol2001，96，： | 1 |
| 5 | Aortoiliac mul- tidetector-row CT angiography with low kV settings: im- proved vessel enhancement and simtdtaneous reduction of radiation dose 显示文摘 | Wintersperger B Jakobs T Herzog P | 2005 | Eur Radiol2005，15，2： | 1 |
| 6 | Photodynamic therapy with 5-aminolevulinic acid is not effective in bile duct cancer显示文摘 | Zoepf T Jakobs R Rosenbaum A | 2001 | Gastrointest Endosc2001，54，6： | 1 |
| 7 | Assessment of the ATP binding properties of Hsp90 显示文摘 | Jakob U Scheibel T Bose S | 1996 | J Biol Chem1996，271，10： | 1 |
| 8 | Oral preanaesthetic medication for children:double blind randomized study of a combination of midazolam and ketamine vs midazolam or ketamine alone显示文摘 | Funk W Jakob W Riedl T | 2000 | Br J Anaesth2000，84，3： | 1 |
| 9 | 显示文摘 | Jakob T Udey MC | 1998 | J Immunol1998，160，8： | 1 |
| 10 | Oral preanaesthetic medication for children:double blind randomized study of a combination of midazolam and ketamine vs midazolam or ketamine alone显示文摘 | Funk W Jakob W Riedl T | 2000 | Br J Anaesth2000，84，： | 1 |
| 11 | Regulation of E-cadherin-mediated adhesion in langerhans cell-like dendritic cells by inflammatory mediators that mobilize langerhans cells in vivo显示文摘 | Jakob T Udey MC | 1998 | J Immunol1998，160，4： | 1 |
| 12 | Multislice helical CT of the heart with retrospective ECG gating: reduction of radiation exposure by ECG-controlled tube current modulation显示文摘 | Jakobs T F Becker C R Ohnesorge B M | 2002 | Eur Radial2002，12，： | 1 |
| 13 | Combined functional and morphological imaging consisting of gated myocardial perfusion SPECT and 16-detector multislice spiral CT angiography in the noninvasive evaluation of coronary artery disease: first experiences 显示文摘 | Hacker M Jakobs T Matthiesen F | 2007 | Clin Imaging2007，31，5： | 1 |
| 14 | Pyridoxine-dependent seizures caused by alpha amino atdipic semialdehyde dehydrogenase deficiency: the first polish case with confirmed biochemical and molecular pathology 显示文摘 | Kaczorowska M Kmiec T Jakobs C | 2012 | J Child Neurol2012，23，12： | 1 |
| 15 | Aorto- iliac multi detector-row CT angiography with low kV seltings:improved vessel enhancement and simuhaneous reduction of radiation dose显示文摘 | Wintersperger B Jakobs T Herzog P | 2005 | Eur Radiol2005，15，2： | 1 |
| 16 | Inkjet printing of conductive patterns with an aqueous solution of without any additional stabilizing ligands显示文摘 | Jahn S F Jakob A Blaudeck T | 2010 | Thin Solid Films2010，518，12： | 1 |
| 17 | Autologous osteochondral grafting in the knee: indication, results, and reflections 显示文摘 | Jakob RP Franz T Gautier E | 2002 | Clin Orthop2002，401，1： | 1 |
| 18 | Comparison of spiral multidetector CT angiography and myocardial perfusion imaging in the noninvasive detection of functionally relevant coronary artery lesions: first clinical experiences显示文摘 | Hacker M Jakobs T Matthiesen F | 2005 | J Nucl Med2005，46，8： | 1 |
| 19 | Sixty-four slice spiral CT angiography does not predict the functional relevance of coronary artery stenoses in patients with stable angina显示文摘 | Hacker M Jakobs T Hack N | 2007 | Eur J Nucl Med Mol Imaging2007，34，1： | 1 |
| 20 | Analyze incipient faults with dissolved gas nomograph 显示文摘 | Church J O Haupert T J Fredi Jakob | 1987 | Electrical World1987，64，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员