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| 1 | A randomized open-label trial of on-demand rabeprazole vs ranitidine for patients with non-erosive reflux disease显示文摘AIM:To compare the efficacy of the proton-pump inhibitor,rabeprazole,with that of the H 2-receptor antagonist,ranitidine,as on-demand therapy for relieving symptoms associated with non-erosive reflux disease(NERD).METHODS:This is a single center,prospective,randomized,open-label trial of on-demand therapy with rabeprazole(group A) vs ranitidine(group B) for 4 wk.Eighty-three patients who presented to the American University of Beirut Medical Center with persistent gastroesophageal reflux disease(GERD) symptoms and a normal upper gastrointestinal endoscopy were eligible for the study.Patients in group A(n = 44) were allowed a maximum rabeprazole dose of 20 mg twice daily,while those in group B(n = 39) were allowed a maximum ranitidine dose of 300 mg twice daily.Efficacy was assessed by patient evaluation of global symptom relief,scores of the SF-36 quality of life(QoL) questionnaires,total number of pills used,and number of medication-free days.RESULTS:Among the 83 patients who were enrolled in the study,76 patients(40 in the rabeprazole group and 36 in the ranitidine group) completed the 4-wk trial.Baseline characteristics were comparable between both groups.After 4 wk,there was no significant difference in the subjective global symptom relief between the rabeprazole and the ranitidine groups(71.4% vs 65.4%,respectively;P = 0.9).There were no statistically significant differences between mean cumulative scores of the SF-36 QoL questionnaire for the two study groups(rabeprazole 22.40 ± 27.53 vs ranitidine 17.28 ± 37.06;P = 0.582).There was no significant difference in the mean number of pills used(rabeprazole 35.70 ± 29.75 vs ranitidine 32.86 ± 26.98;P = 0.66).There was also no statistically significant difference in the mean number of medication-free days between both groups.CONCLUSION:Rabeprazole has a comparable efficacy compared to ranitidine when given on-demand for the treatment of NERD.Both medications were associated with improved quality of life. | Abdallah A Kobeissy Jana G Hashash Faek R Jamali Assaad M Skoury Reham Haddad Sarah El-Samad Rami Ladki Rola Aswad Assaad M Soweid | 2012 | World Journal of Gastroenterology2012，18，19： | 4 |
| 2 | Posterior lingual lidocaine: A novel method to improve tolerance in upper gastrointestinal endoscopy显示文摘AIM: To evaluate the effect of posterior lingual lidocaine swab on patient tolerance to esophagogastro-duodenoscopy, the ease of performance of the procedure, and to determine if such use will reduce the need for intravenous sedation. METHODS: Eighty patients undergoing diagnostic esophagogastroduodenoscopy in a tertiary care medical center were randomized to either lidocaine swab or spray. Intravenous meperidine and midazolam were given as needed during the procedure. RESULTS: Patients in the lidocaine swab group (SWG) tolerated the procedure better than those in the spray group (SPG) with a median tolerability score of 2 (1, 4) compared to 4 (2, 5) (P < 0.01). The endoscopists encountered less diffi culty performing the proceduresin the SWG with lower median difficulty scores of 1 (1, 5) compared to 4 (1, 5) in the SPG (P < 0.01). In addition, the need for intravenous sedation was also lower in the SWG compared to the SPG with fewer patients requiring intravenous sedation (13/40 patients vs 38/40 patients, respectively, P < 0.01). The patients in the SWG were more satisfi ed with the mode of local anesthesia they received as compared to the SPG. In addition, the endoscopists were happier with the use of lidocaine swab. CONCLUSION: The use of a posterior lingual lidocaine swab in esophagogastroduodenoscopy improves patient comfort and tolerance and endoscopist satisfaction and decreases the need for intravenous sedation. | Assaad M Soweid Shadi R Yaghi Faek R Jamali Abdallah A Kobeissy Michella E Mallat Rola Hussein Chakib M Ayoub | 2011 | World Journal of Gastroenterology2011，17，47： | 2 |
| 3 | The catastrophic 2008 -2009 red fide in the Arabian gulf region, with observations on the identification and phylogeny of the fish-killing dinoflagellate Gochlodinium polykrikoides显示文摘 | RICHLEN M L MORTON S L JAMALI E A | 2010 | Harmful Algae2010，9，： | 1 |
| 4 | Comparison of corneal and anterior chamber parameters following myopic laser in situ keratomileusis and photorefractive keratectomy by Pentacam as a new imaging technique显示文摘 | Zare MA Hashemi H Jamali M | 2011 | Iran J Ophthalmo12011，23，1： | 1 |
| 5 | Intelligent washing ma- x chine : a bioinspired and multi-objective approach 显示文摘 | MILASI R M JAMALI M R LUCAS C | 2007 | Interna- tional Journal of Control Automation and Systems2007，5，4： | 1 |
| 6 | Student digital information-seeking behavior in context显示文摘 | Nicholas D Huntington P Jamali H R Rowlands I Fieldhouse M | 2009 | Journal of Documentation2009，65，1： | 1 |
| 7 | An integrated production and preventive maintenance planning model显示文摘 | Aghezzaf E H Jamali M A Ait-Kadi D | 2007 | European Journal of Operational Research2007，181，： | 1 |
| 8 | Speciation of heavy metals in sediment by conventional,ultrasound and microwave assisted singleextraction methods: A comparison with modified sequential extraction procedure显示文摘 | ARAIN M B KAZI T G JAMALI M K | 2008 | J Hazard Mater2008，154，3： | 1 |
| 9 | The Comparison of WHOQOLBREF with disease specific heath related quality of life questionnaire in irritable bowel syndrome显示文摘 | Jamali R Biglari M | 2015 | Acta Med Iran2015，53，： | 1 |
| 10 | Application of factorial design in optimization of ultrasonic - assisted extraction of aluminum in juices and soft drinks 显示文摘 | Nusrat Jalbani Tasnecm G Kazi Bilal M Arain M K Jamali Hassan I Afridi R A Sarfraz | 2006 | Talanta2006，，70： | 1 |
| 11 | Assessment of water quality of polluted lake using multivariate statistical techniques:A case study显示文摘 | Kazi T G Arain M B Jamali M K | 2009 | Ecotoxicology and Environmental Safety2009，72，2： | 1 |
| 12 | Pharmacokinetics of celecoxib in the presence and absence of interferon-induced acute inflammation in the rat:application of a novel HPLC assayp显示文摘 | Guirguis M S Sattari S Jamali F | 2001 | J Pharm Sci2001，4，1： | 1 |
| 13 | Nkx2- 5 activity is essential for cardiomyogenesis显示文摘 | Jamali M Rogerson PJ Wilton S | 2001 | J Biol Chem2001，276，42： | 1 |
| 14 | Predicting prognosis in gastroentero-pancreatic neuroendocrine tumor: an overview and the value of Ki-67 immunostaining显示文摘 | Jamali M Chetty R | 2008 | Endocr Pathol2008，19，4： | 1 |
| 15 | NKx2-5 activity is essential for cardiomyogenesis 显示文摘 | Jamali M Rogerson PJ Wilton S | 2001 | J Biol Chem2001，276，42： | 1 |
| 16 | Cooperative effect of angiotensin AT1 and endothelin ETA receptor antagonism limits the brain damage after ischemic stroke in rat显示文摘 | Stenman E Jamali R Henriksson M | 2007 | European Journal of Phamaeology2007，570，13： | 1 |
| 17 | Assessment of water quality of polluted lake using multivariate statistical techniques: A case study 显示文摘 | Kazi T G Arain M B Jamali M K | 2009 | Ecotoxicology and Environmental Safety2009，72，2： | 1 |
| 18 | Assessment of water quality of polluted lake using multivariate statistical techniques: a case study显示文摘 | KAZI T G ARAIN M B JAMALI M K | 2009 | Ecotoxicology and Environmental Safety2009，72，： | 1 |
| 19 | Solving the problem of packing equal and unequal cir cles in a circular container显示文摘 | Grosso A Jamali A R M J U Locatelli M | | 0，，01： | 1 |
| 20 | Continuous glucose monitoring system signals the occurrence of marked postprandial hyperglycemia in the elderly显示文摘 | Jamali R Bachrach-Lindstr(o)m M Mohseni S | | 0，，03： | 1 |
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