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| 1 | 利用深度卷积神经网络分析超声图像进行肝纤维化自动分类显示文摘无创评估肝纤维化进程是目前临床研究的热点。瞬时弹性成像、剪切波弹性成像和磁共振(MRI)弹性成像得到越来越多的应用。针对CT和MRI图像的深度卷积神经网络(DCNN)评估肝纤维化显示出较高的诊断效能,而针对B型超声图像进行深度学习的报道较少。该研究通过建立深度卷积神经网络对B型超声图像预测肝纤维化METAVIR评分。收集两个专科院校转诊中心的3446例患者的13608张超声图像用于训练DCNN,患者接受手术切除、肝穿刺活检或瞬时弹性成像检查,以病理标本或瞬时弹性成像得出估计的METAVIR分数用作参考标准,建立四分类模型(F0比F1比F23比F4)。 | Lee JH Joo I Kang TW 薛立云(编译) | 2020 | 中华医学杂志2020，100，39： | 11 |
| 2 | Is obesity associated with gastropharyngeal reflux disease?显示文摘AIM: To examine the association between obesity and gastropharyngeal reflux disease (GPRD) as well as gastroesophageal reflux disease (GERD) METHODS: We conducted a cross-sectional study of consecutive patients undergoing ambulatory 24-h dual-probe pH monitoring from July 2003 to December 2006. The association between body mass index (BMI) and parameters about gastroesophageal or gastropharyngeal reflux was examined in univariate and multivariate analyses.RESULTS: A total of 769 patients (307 men and 462 women; mean age 50.7 years) were finally enrolled. Most variables showing gastroesophageal reflux was higher in the obese patients than the patients with normal BMI. There was no difference in all the variables showing gastropharyngeal reflux according to the BMI. After adjustment for age, sex, alcohol intake and smoking, obese patients demonstrated an about 2-fold increase in risk of GERD compared with patients with normal BMI (OR, 1.9; 95 CI, 1.3-2.9), but overweight patients did not demonstrate increased risk of GERD (OR, 1.2; 95 CI, 0.8-1.7). Both obese patients and overweight patients did not demonstrated increased risk of GPRD compared with patients with normal BMI (OR, 1.1; 95 CI, 0.8-1.7; and OR, 0.9; 95 CI, 0.6-1.3, respectively).CONCLUSION: Obesity is not associated with GPRD reflux while it is associated with GERD. | Cheol Woong Choi Gwang Ha Kim Chul Soo Song Soo Geun Wang Byung Joo Lee Hoseok I Dae Hwan Kang Geun Am Song | 2008 | World Journal of Gastroenterology2008，14，2： | 5 |
| 3 | Auxin-induced reactive oxygen species production requires the activation of phosphatidylinositol 3 - kinase 显示文摘 | Joo J H Yoo H J Hwang I | 2005 | FEBS Letters2005，579，： | 1 |
| 4 | Large - scale nonhydrolytic sol- gel synthesis of uniform- sized ceria nanocrystals with spherical, wWire, and tadpole shapes 显示文摘 | Yu T Joo J Park Y I | 2005 | Ange- wandte Chemie2005，117，45： | 1 |
| 5 | Prospective comparison of 3T MRI with diffusion weighted imaging and MDCT for the preoperative TNM staging of gastric cancer显示文摘 | Joo I Lee JM Kim JH | 2015 | J Magn Reson Imaging2015，41，3： | 1 |
| 6 | Elevated MMP - 12 protein levels in induced sputum from patients with COPD 显示文摘 | Demedts I K Morel - Montero A Lebecque S Pacheco Y Cataldo D Joos G F Pauwels R A Brusselle G G | 2006 | Thorax2006，61，6： | 1 |
| 7 | A modified serum neutralization test for the detection of antibody to porcine reproductive and respiratory syndrome virus in swine sera 显示文摘 | Yoon I J Joo H S Goval S M | 1994 | J Vet Diagn Invest1994，6，3： | 1 |
| 8 | TUT4 in concertwith Lin28 suppresses microRNA biogenesisthrough pre-microRNA uridylation 显示文摘 | Heo I Joo C Kim YK | 2009 | Cell2009，138，4： | 1 |
| 9 | Inhibition of cytokine-induced β cell apoptosis via laccase and its therapeutic advantages for insulin-dependent diabetes mellitus,type 1 diabetes显示文摘 | Joo SS Lee do I Hwang KW | | 0，，11： | 1 |
| 10 | Liver matastases on quantitative tolor mapping of the arterial enhancement faction frommultiphasic CT scans: evaluation of the hemodynamic features and correlation with the chemotherapy response 显示文摘 | Joo I Lee JM Kim KW | 2011 | Eur J Radiol2011，80，3： | 1 |
| 11 | Ordered nanoporous arrays of car- bon supporting high dispersions of platinum nanoparticles显示文摘 | Joo S H Choi S J Oh I | 2001 | Na~ ture2001，412，6843： | 1 |
| 12 | Elevated MMP- 12 proteinlevels in induced sputum from patients with COPD 显示文摘 | Demedts I K Morel- Montero A Lebecque S Pacheco Y Cataldo D Joos G F Pauwels R A Brusselle G G | 2006 | Thorax2006，61，3： | 1 |
| 13 | Effects of dietary conjugated linoleic acid on fatty acid composition,lipid oxidation,color, and water-holding capacity of pork loin 显示文摘 | JOO S T LEE J I HA Y L | 2002 | J Anita Sci2002，80，： | 1 |
| 14 | Electrical stress effect on poly-Si thin film transistors fabricated by metal induced lateral crystallization显示文摘 | IHN T H LEE B I JOO S K | 1997 | Jap J Appl Phys1997，36，： | 1 |
| 15 | Anew process for production of hot metal from fine ore and coal显示文摘 | KIM H G LEE I O | 1999 | Scandinavian Journal of Metallurgy1999，28，： | 1 |
| 16 | Evaluation of the impact of a pharmaceutical care program in children with asthma显示文摘 | Gonzalez-Martin G Joo I Sanchez I | 2003 | Patient Educ Couns2003，49，： | 1 |
| 17 | Prevalence of excessive daytime sleepiness and associated factors in the adult population of Korea显示文摘 | Joo S Baik I Yi H | | 0，，： | 1 |
| 18 | Supracricoid laryngectomy: oncologic validity and functional safety 显示文摘 | CHO K J JOO Y H SUN D I | 2010 | Eur Arch Otorhinolaryngol2010，267，： | 1 |
| 19 | Differential ex- pression of skeletal muscle proteins in high-fat diet- fed rats in response to capsaicin feeding显示文摘 | KIM D H JOO J I CHOI J W | 2010 | Pro teomics2010，10，28： | 1 |
| 20 | TLrF4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation 显示文摘 | Heo I Joo C Kim YK | 2009 | Cell2009，138，4： | 1 |
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