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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Specific asso- ciation of annexin 1 with plasma membrane - resident and internalized EGF receptors mediated through the protein core domain 显示文摘 | Susanne R Judith A Francoise Russo - Marieb | 2004 | FEBS Letters2004，578，12： | 1 |
| 3 | Gemini virus-mediated genesilencing firom cotton leaf crumple virus is enhanced by low tempera-ture in cotton显示文摘 | John R T Idris A M Judith K B | 2008 | Plant Physiology2008，1148，： | 1 |
| 4 | Anaphylaxis after administration of ibritumomab tiuxetan for follicular non-Hodgkin lymphoma显示文摘 | Jankowitz R Judith J Samuel A | 2008 | Clinical Nuclear Medicine2008，22，33： | 1 |
| 5 | Universal infant hearing screening by automated auditory brainstem response measurement显示文摘 | Judith A Mason Kenneth R Herrmann | 1998 | Pediatrics1998，101，： | 1 |
| 6 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 7 | Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials显示文摘 | Rod S Taylor Allan Brown Shah Ebrahim Judith Jolliffe Hussein Noorani Karen Rees Becky Skidmore James A Stone David R Thompson Neil Oldridge | 2004 | The American Journal of Medicine2004，，10： | 1 |
| 8 | Class formation in Nineteenth - Century Americas:the case of the middle class 显示文摘 | Melanie A and Judith R B | 1993 | Annual Review of Sociology1993，19，： | 1 |
| 9 | Molybdenum Intake Influences Molybdenum Kinetics in Men显示文摘 | Janet A N Judith R T | 2007 | The American Society forNutrition J Nutr2007，137，： | 1 |
| 10 | Diffuse backscattering Mueller matrices of highly scattering media显示文摘 | Andreas H H Angelia A E Judith R M | 1997 | Optics Express1997，1，13： | 1 |
| 11 | Diffuse backscattering Mueller matrices of highly scattering media显示文摘 | Hielscher Andreas H Eick Angelia A Mourant Judith R | 1997 | Optics Express1997，1，13： | 1 |
| 12 | Long-term effects of aided phytostabilisation of trace elements on microbial biomass and activity, enzyme activities, and composition of microbial community in the Jales contaminated mine spoils显示文摘 | Giancarlo R Loretta L Judith A | 2008 | Environmental Pollution2008，152，3： | 1 |
| 13 | Patient-centered care and adherence:definitions and applications to improve outcomes显示文摘 | Janice H R Lynn C C Judith A B | 2008 | J AANP2008，20，1： | 1 |
| 14 | Impact of thrombolysis, intra-aortic balloon pump counterpulsation, and their combination in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry显示文摘 | Timothy A Sanborn Lynn A Sleeper Eric R Bates Alice K Jacobs Jean Boland John K French Jo Dens Vladimir Dzavik Sebastian T Palmeri John G Webb Mark Goldberger Judith S Hochman | 2000 | Journal of the American College of Cardiology2000，，： | 1 |
| 15 | Analysis of stress distribution in lumbar interbody fusion显示文摘 | Kumar N Judith M R Kumar A | 2005 | Spine2005，30，15： | 1 |
| 16 | Assessing Students' Performances in a Competency-based Curriculum显示文摘 | Richurd H Dollase Judith A Boss | 2003 | Acad Med2003，78，： | 1 |
| 17 | Sleep disturbanee in cancer patients显示文摘 | Judith R Davidson A listair W | 2002 | Social Seienc Medicine2002，54，： | 1 |
| 18 | The effects of mucositis on quali- ty of life in patients with head and neck cancer显示文摘 | Judith A Armstrong R | 2006 | Clin J Oncol Nuts2006，10，1： | 1 |
| 19 | Effe-gi,Magness-Taylor, and instron fruit pressure testing devices for apples, peaches, and nectarines显示文摘 | Judith A A Alley E W David R M | 1976 | J Amer Hort Sci1976，101，6： | 1 |
| 20 | Variation in newborn size according to pregnancy weight change by trimester显示文摘 | Judith E B Maureen A M David R J | 2002 | American Journal of Clinical Nutrition2002，76，1： | 1 |
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