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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Current state of endohepatology: Diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound显示文摘The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to evolve.Although there are established“standards of care”in liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic approach.The concept of“Endo Hepatology”has been used to describe of the applications of endoscopic ultrasound(EUS)to these challenges.EUS-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic lobes.Furthermore,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPG)measurements,allowing for the collection of valuable diagnostic and prognostic data.EUS-guided PPG measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein pressure.In addition,EUS-guided treatment of gastric varices(GV)offers several possible advantages to current therapies.EUS-guided treatment of GV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound visualization.The appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety. | Sean R Rudnick Jason D Conway Mark W Russo | 2021 | World Journal of Hepatology2021，13，8： | 4 |
| 3 | Using events as a mapping concept that complement existing ROS methods显示文摘 | Chad D PierskaUaa Jason M Siniscalchia Steven W Selina | 2007 | Leisure Sciences2007，29，1： | 1 |
| 4 | White Light Emission Using Excimers in Electrophosphorescent Organic Light-Emitting Devices显示文摘 | BRIAN W D'ANDRADE JASON BROOKS VADIM ADAMOVICH | 2002 | Adv Mater2002，14，15： | 1 |
| 5 | Sterilization affects soil organic matter chemistry and bioaccumulation of spiked p, p' - DDE and anthracene by earthworms 显示文摘 | Jason W K Ilya B S Richard D P | 2010 | Environmental Pol- lution2010，158，： | 1 |
| 6 | Voluntary Disclosure of Segment Information 显示文摘 | Mitchell Jason D Chia Chris W L Loh Andrew S | 1995 | Accounting and Fi nance1995，35，： | 1 |
| 7 | Computational identification of cis-regulatory elements associated groups of functionaily related genes in Saccharomyces cetevisiae显示文摘 | Jason D Hughes Preston W Estep Saeed Tavazoie George M Church | 2000 | J Mol Biol2000，296，5： | 1 |
| 8 | Circulat- ing and dietary magnesium and risk of cardiovascular disease:A systematic review and meta-analysis of pro- spective studies 显示文摘 | Liana C D G Fumiaki I Jason H Y W | 2013 | Am J Clin Nutr2013，98，1： | 1 |
| 9 | Network Dy- namics and Field Evolution : The Growth of Interorganizational Col- laboration in the Life Sciences 显示文摘 | Powell W W White D R Koput K W Jason O S | 2005 | American Journal of Sociology2005，110，4： | 1 |
| 10 | Formation and control of box-shaped ultra-shallow junction using laser annealing and pre-amorphization implantation显示文摘 | Kim S D Park C M Jason C S W | 2005 | Solid-State Electronics2005，49，1： | 1 |
| 11 | Formation of hydrate slurries in a once-through operation显示文摘 | LACHANCE Jason W TALLEY Larry D SHATTO Don P | 2012 | Energy&Fuels2012，26，7： | 1 |
| 12 | Effects of the combination treatment of raloxifene and alendronate on the biomechanical properties of vertebral bone显示文摘 | Tamim D Jason W Susan R | 2011 | J Bone Miner Res2011，26，： | 1 |
| 13 | HPLC analysis of plant DNA methylation:a study of critical methodological factors显示文摘 | Jason J W Harding K Bremner D H | 2005 | Plant Physiology and Biochemistry2005，43，9： | 1 |
| 14 | The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial显示文摘 | Natalie C Ward Jason HY Wu Michael W Clarke Ian B Puddey Valerie Burke Kevin D Croft Jonathan M Hodgson | 2007 | Journal of Hypertension2007，，1： | 1 |
| 15 | Devel- opment and application of a muhimodal contrast ggent for SPECT/CT hybrid imaging 显示文摘 | Jason M C Lawrence W D Zhen W Z etal | 2011 | Bioconjug Chem2011，22，： | 1 |
| 16 | Estimation of relative satellite position using transformed differential carrier-phase GPS measurements 显示文摘 | Jonathan D W Jason L S | 2007 | Journal of Guidance Control and Dynamics2007，30，5： | 1 |
| 17 | Improved integer ambiguity resolution technique for fixed arrays 显示文摘 | Jonathan D W Jason L S | 2005 | Journal of Guidance Control and Dynamics2005，28，4： | 1 |
| 18 | Surface passivation of bare aluminum nanoparticles using perfluoroalkyl carboxylic acids 显示文摘 | Jason J R Andrea D W David M R | 2005 | Chem Mater2005，，17： | 1 |
| 19 | Evaluation of a new method for measurement of minute ventilation recovery time显示文摘 | Christopher W Seymour MD Jason D | | 0，，2： | 1 |
| 20 | Surface passivation of bare aluminum nanoparticles using perfluoroalkyl carboxylic acids显示文摘 | Jason J R Andrea W D David R M | 2005 | Chem Mater2005，17，11： | 1 |
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