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802篇 您的检索式:作者名="Jens D"
    题名 作者 年代 出处 被引量
1Brain changes in diabetes mellitus patients withgastrointestinal symptoms显示文摘Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock Jens B Frøkjær Klaus Krogh Asbjørn M Drewes 2016World Journal of Diabetes2016,7,2:4
2Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group显示文摘Uwe Pelzer Ingo Schwaner Jens Stieler Mathias Adler J?rg Seraphin Bernd D?rken Hanno Riess Helmut Oettle 2011European Journal of Cancer2011,,11:2
3Modification of Cullender and Smith equation for more accurate bottom hole pressure calculation in gas wells显示文摘ODEN R D JENNINGS J W 1988Society of Petroleum Engineers1988,35,3:1
4Power modeling and low-power design of content addressable memories 显示文摘Hsiao H Y L Wang D H Jen C W 2001Circuits and System2001,4,:1
5Argumentationbased negotiation显示文摘Rahwan I Ramchum S D Jennings N R 2004Knowledge Engineering Review2004,18,4:1
6Factors influencing the distribution of blackchin tilapia Sarotherodon melanotheron ( Osteichthyes : Cichlidae ) in the Indian River system, Florida 显示文摘Jennings D P Williams J D 1992Northeast Gulf Science1992,12,2:1
7Laboratory D-dimer measurement, improved agreement between methods through cali- bration显示文摘Jennings I Woods TA Kitchen D 2007Thromb Haemost2007,98,5:1
8Insights between environmentalscanning activities and Porter's generic strategies: an empirical analysis 显示文摘JENNINGS D F LUMPKIN J R Journal of M anagement0,18,4:1
9The ante- cedents and consequences of firm-level entrepreneurship: the state of the field 显示文摘ZAHRA S A JENNINGS D F KURATKO D F 1999Entrepreneurship Theory and Practice1999,,24:1
10Agricultural women in Central Queensland and changing modes of production: a preliminary exploration of the issues显示文摘Jennings G Stehlik D 2000Rural Society2000,10,1:1
11A novel route for the preparation of dimeric tetraorganodistannoxanes 显示文摘JENS B DAINIS D VONG S K 2002J Organomet Chem2002,659,:1
12Metabolic flux analysis in mammalian cell culture 显示文摘Lake E Q Stefanie D Jens 0 K 2010Metab Eng2010,12,:1
13Carabid beetles (Coleoptera: Carabidae) associated with strip clearcut and dense spruce-fir forests of Maine显示文摘JENNINGS D T HOUSEWEART M W DUNN G A 1986The Coleopterists Bulletin1986,40,3:1
14The GAIA methodology for agent oriented analysis and design显示文摘Wooldridge M Jennings N R Kinny D 2000Autonomous Agents Multi-agent System2000,3,3:1
15Recent advances in flow cytometry:application to the diagnosis of hematologic malignancy 显示文摘JENNINGS C D and FOON K A 1997Blood1997,90,8:1
16Hydrogels for cell immobilization 显示文摘Jen C R Hancher D J 1996Biotechnology and Bioengineering1996,50,4:1
17Structural characterization of two aquaporins isolated from native spinach leaf plasma membranes显示文摘FOTIADIS D JEN P MINI T 2001J Biol Chem2001,276,3:1
18Effects of hydrogel/ silver coatings on in vitro adhesion to catheters of bacteria associated with urinary tract infection显示文摘AHEAM D G GRACE D T JENNINGS M J 2000Curr Microbiol2000,41,2:1
19Assessing forest canopies and understorey illumination:canopy closure,canopy cover and other measures显示文摘JENNINGS S B BROWN N D SHEIL D 1999Forestry1999,72,:1
20Attempts to detect transgenic and endogenous plant DNA and transgenic protein in muscle from broilers fed Yield Gard corn Borer corn显示文摘Jennings J C Aibee L D Kolwyck D C 2003Point Science2003,82,3:1
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