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| 1 | Intentional ingestions of foreign objects among prisoners: A review显示文摘The intentional ingestion of foreign objects(IIFO) is described more commonly in prison populations than in the general population, with an estimated annual incidence of 1 in 1900 inmates in our state correctional facilities. Incidents often involve ingestion of small metal objects(e.g., paperclips, razor blades) or other commonly available items like pens or eating utensils. Despite ingestion of relatively sharp objects, most episodes can be clinically managed with either observation or endoscopy. Surgery should be reserved for those with signs or symptoms of gastrointestinal perforation or obstruction. For those with a history of IIFO, efforts should focus on prevention of recurrenceas subsequent episodes are associated with higher morbidity, significant healthcare and security costs. The pattern of IIFO is often repetitive, with escalation both in frequency of ingestions and in number of items ingested. Little is known about successful prevention strategies, but efforts to monitor patients and provide psychiatric care are potential best-practice strategies. This article aims to provide state-of-the art review on the topic, followed by a set of basic recommendations. | David C Evans Thomas R Wojda Christian D Jones Andrew J Otey Stanislaw P Stawicki | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，3： | 10 |
| 2 | Dyslipidemia management in primary prevention of cardiovascular disease:Current guidelines and strategies显示文摘Cardiovascular disease is the leading cause of death in the United States. In 2010, the Centers for Disease Control and Prevention estimated that $444 billion was spent on cardiovascular diseases alone, about $1 of every $6 spent on health care. As life expectancy continues to increase, this annual cost will also increase, making costeffective primary prevention of cardiovascular disease highly desirable. Because of its role in development of atherosclerosis and clinical events, dyslipidemia management is a high priority in cardiovascular prevention. Multiple major dyslipidemia guidelines have been published around the world recently, four of them by independent organizations in the United States alone. They share the goal of providing clinical guidance on optimal dyslipidemia management, but guidelines differ in their emphasis on pharmacotherapy, stratification of groups, emphasis on lifestyle modification, and use of a fixed target or percentage reduction in low density lipoprotein cholesterol. This review summarizes eight major guidelines for dyslipidemia management and considers the basis for their recommendations. Our primary aim is to enhance understanding of dyslipidemia management guidelines in patient care for primary prevention of future cardiovascular risk. | Aditya D Hendrani Tolulope Adesiyun Renato Quispe Steven R Jones Neil J Stone Roger S Blumenthal Seth S Martin | 2016 | World Journal of Cardiology2016，8，2： | 5 |
| 3 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 4 | Macrophage secretory products induce an inflammatory phenotype in hepatocytes显示文摘AIM:To investigate the influence of macrophages on hepatocyte phenotype and function.METHODS:Macrophages were differentiated from THP-1 monocytes via phorbol myristate acetate stimulation and the effects of monocyte or macrophageconditioned medium on HepG2 mRNA and protein expression determined.The in vivo relevance of these findings was confirmed using liver biopsies from 147 patients with hepatitis C virus(HCV)infection.RESULTS:Conditioned media from macrophages,but not monocytes,induced a transient morphological change in hepatocytes associated with upregulation of vimentin(7.8±2.5-fold,P=0.045)and transforming growth factor(TGF)-β1(2.6±0.2-fold,P<0.001)and downregulation of epithelial cadherin(1.7±0.02-fold,P=0.017)mRNA expression.Microarray analysis revealed significant upregulation of lipocalin-2(17-fold,P <0.001)and pathways associated with inflammation,and substantial downregulation of pathways related to hepatocyte function.In patients with chronic HCV,realtime polymerase chain reaction and immunohistochemistry confirmed an increase in lipocalin-2 mRNA(F0 1.0 ±0.3,F1 2.2±0.2,F2 3.0±9.3,F3/4 4.0±0.8,P= 0.003)and protein expression(F1 1.0±0.5,F2 1.3± 0.4,F3/4 3.6±0.4,P=0.014)with increasing liver injury.High performance liquid chromatography-tandem mass spectrometry analysis identified elevated levels of matrix metalloproteinase(MMP)-9 in macrophageconditioned medium,and a chemical inhibitor of MMP-9 attenuated the change in morphology and mRNA expression of TGF-β1(2.9±0.2 vs 1.04±0.1,P<0.001) in macrophage-conditioned media treated HepG2 cells.In patients with chronic HCV infection,hepatic mRNA expression of CD163(F0 1.0±0.2,F1/2 2.8±0.3,F3/4 5.3±1.0,P=0.001)and MMP-9(F0 1.0±0.4,F1/2 2.8±0.3,F3/4 4.1±0.8,P=0.011)was significantly associated with increasing stage of fibrosis.CONCLUSION:Secreted macrophage products alter the phenotype and function of hepatocytes,with increased expression of inflammatory mediators,suggesting that hepatocytes actively participate in liver injury. | Michelle Melino Victoria L Gadd Gene V Walker Richard Skoien Helen D Barrie Dinesh Jothimani Leigh Horsfall Alun Jones Matthew J Sweet Gethin P Thomas Andrew D Clouston Julie R Jonsson Elizabeth E Powell | 2012 | World Journal of Gastroenterology2012，18，15： | 3 |
| 5 | Insulin-like growth factors and their binding proteins: biological actions显示文摘 | Jones J R Clemmons D R | 1995 | Endocr Rev1995，16，： | 2 |
| 6 | 欧洲鼻腔鼻窦解剖术语意见书(二)显示文摘2014年,Rhinology刊登了European Position Paper on the Anatomical Terminology of the Internal Nose and Paranasal Sinuses,对于认识鼻科解剖名词具有重要的普及意义。考虑到国内耳鼻喉科医师获取和阅读英文文献的能力有限,但是又急需及时掌握学科领域内解剖名词的表述,我们通过与Rhinology编辑部及作者联系征得同意,翻译而成《欧洲鼻腔鼻窦解剖术语规范意见书》(以下简称《意见书》)。《意见书》中的所有解剖名词同时参考国内《英汉汉英医学分科词典(耳鼻咽喉科学分册)》进行统一,对于《英汉汉英医学分科词典(耳鼻咽喉科学分册)》中没有提及的名词给出了相应的补充。希望《意见书》对国内耳鼻喉科医师掌握并规范应用鼻科名词提供参考。《中国眼耳鼻喉科杂志》从第17卷第2期开始以连载形式刊登《意见书》。 | 王德辉 王德云 于华鹏 孙希才 李晗 刘琢扶 刘全 张焕康 Lund VJ Stammberger H Fokkens WJ Beale T Bernal-Sprekelsen M Eloy P Georgalas C Gerstenberger C Hellings PW Herman P Hosemann WG Jankowski R Jones N Jorissen M Leunig A Onerci M Rimmer J Rombaux P Simmen D Tomazic PV Tschabitscher M Welge-Luessen A | 2017 | 中国眼耳鼻喉科杂志2017，17，3： | 2 |
| 7 | The chemokine receptor CXCR3 is expressed in a subset of B-cell lymphomas and is a marker of B-cell chronic lymphocytic leukemia 显示文摘 | Jones D Benjamin R Shahsafaei A | 2000 | Blood2000，95，： | 2 |
| 8 | Maximum and minimum temperature trends for the Globe显示文摘 | Easterling David R Horton Briony Jones Philip D | 1997 | Science1997，277，： | 1 |
| 9 | Nature of band-gap states in V-doped TiO2 revealed by resonant photoemission显示文摘 | DIXON R JONES F H | 1997 | Phys Rew B1997，55，16： | 1 |
| 10 | A new marineammonium-oxidizing bacterium, Nitrosomonas cryotolerans 显示文摘 | Jones R D Morita R Y Koops H P | 1988 | Can J Microbiol1988，34，： | 1 |
| 11 | Efficient whole- cell biotransformation in a biphasic ionic liquid/water system 显示文摘 | Pfruender H Jones R Weuster- Botz D | 2004 | Angew Chem Int Ed Engl2004，43，： | 1 |
| 12 | Efficient global optimization of expensive black-box functions 显示文摘 | Jones D R Schonlau M Welch W J | 1998 | Journal of Global Optimization1998，13，4： | 1 |
| 13 | Thermal Properties of DMNB, A Detection Agent for Exploslves显示文摘 | JONES D E G LIGHTFOOT P D FOUCHARD R C | 2002 | Thermochimic Acta2002，388，12： | 1 |
| 14 | The efficacy of spinosad against the western flower thrips,Frankliniella occidentalis,and its impact on associated biological control agents on greenhouse cucumbers in southern Ontario显示文摘 | Jones T Scott D C Harris R | 2005 | Pest Manag Sci2005，61，： | 1 |
| 15 | Northern Hemisphere surface air temperature variations: 1851-- 1984显示文摘 | Jones P D S C B Raper R S Bradley | 1986 | JClim Appl Meteor1986，25，2： | 1 |
| 16 | 显示文摘 | MARTIN P D JONES G R STRINGER F WILSON I D | 2003 | Analyst2003，128，： | 1 |
| 17 | Insulin-like growth factor and their binding proteins:Biological action显示文摘 | JONES J I CLEMMONS D R | 1995 | Endocr Rev1995，16，： | 1 |
| 18 | The human papillomavirus E7 oncoprotein can uncouple celluar differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2显示文摘 | Jones D L Alani R M | 1997 | Genes1997，11，： | 1 |
| 19 | Comparative wear under four different tribological conditions of acetylene enhanced cross-linked ultra high molecularweight polyethylene显示文摘 | Marrs H Barton D C Jones R A | 1999 | J Mater Sci:Mater Med1999，10，： | 1 |
| 20 | The location theory of the plantation显示文摘 | JONES D W KRUMMEL J R | 1987 | Journal of Regional Science1987，27，2： | 1 |
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