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| 1 | 马来西亚大学医学中心角膜溃疡的回顾分析显示文摘目的:分析角膜溃疡的病例分布、危险因素、临床特点、微生物检查及预后结果。方法:对2003-07/2006-04就诊于马来西亚大学医学中心的84例(87眼)患者进行研究,其中1例双眼发病,另1例曾因疱疹性角膜炎复发3次就诊。选入标准包括角膜上皮缺损、角膜基质浸润及炎症。结果:患者84例中有男46例,女38例。主要是马来人(52%)。3个主要的危险因素是角膜接触镜的配戴(47%),眼外伤(25%)及眼表疾病(24%)。在老年患者中,糖尿病(8%)及高血压(9%)是重要的系统性疾病。阳性为25%,而微生物培养阳性为73%。在各危险因素组中,绿脓杆菌是最常见的致病菌,在角膜接触镜配戴者中最高。耐庆大霉素革兰染色阴性菌有2例,耐青霉素表皮葡萄球菌有1例。75%的患者溃疡愈合,遗留角膜混浊。2mo后,54%的患眼最佳矫正视力〉6/18,14%〈3/60。3例患者需要行眼球摘除或剜除术。结论:角膜接触镜配戴和眼外伤是青年人群中主要的可预防性危险因素,相反,眼疾是老年人中不可预防的危险因素。超过60%的培养阳性病例为革兰染色阴性菌。 | A J Kadir A Samsudin A Fauzi , Z Z Abidin | 2008 | 国际眼科杂志2008，8，12： | 3 |
| 2 | Specific and cross-reactive immune response against Mycobacterium tuberculosis antigens in mice immunized with proteoliposomes from Mycobacterium bovis BCG显示文摘Objective: To characterize the immunogenicity and the induction of cross-reactive responses against Mycobacterium tuberculosis(M. tuberculosis) of a proteoliposome(PL)from Mycobacterium bovis Bacillus Calmette–Guerin(BCG) with and without alum hydroxide(AL) as adjuvant(PLBCG-AL and PLBCG, respectively) in BALB/c mice.Methods: BALB/c mice were inoculated with phosphate buffer solution, BCG, PLBCG and PLBCG-AL. The humoral immunogenicity was determined by ELISA [immunoglobulin G(Ig G), Ig G1 and Ig G2a] and the cellular immunogenicity was evaluated in vivo by delayed type hypersensitivity. The humoral cross-reactive response against M. tuberculosis was determined by Western blot.Results: Sera from animals immunized with PLBCG-AL and PLBCG showed significant increase in specific total Ig G and Ig G1 antibodies and the presence of cross-reactive antibodies against M. tuberculosis antigens, which were more intense with the use of alum as adjuvant. Mice immunized with PLBCG and PLBCG-AL also showed a specific cellular response in vivo.Conclusions: The cellular and humoral immunogenicity of PLBCG and the capacity to induce cross-reactive responses against M. tuberculosis is in agreement with the protective capacity previously demonstrated by this vaccine candidate and supports the continuation of its evaluation in further stages. | Nadine Alvarez DaymíSerpa Ramlah Kadir Yanely Tirado Reinier Borrero Sonsire Fernández Rubén Cabrera Yolanda Valdes Caridad Zayas Reinaldo Acevedo Luis Izquierdo María Elena Sarmiento Mohd-Nor Norazmi JoséLuis Pérez Armando Acosta | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，3： | 3 |
| 3 | The effects of partially sub-string Indian carp or adding silver carp on poly-cultures inclu-ding small indigenous fish species ( SIS) 显示文摘 | Milstein A Kadir A Wahab M | 2008 | Aquaculture2008，279，14： | 1 |
| 4 | Bacterial ferritin contains 24 hame groups显示文摘 | KADIR F H A MOORE G R | 1990 | F E B S Lett1990，271，： | 1 |
| 5 | Dynamic changes in PET amy- loid and FDG imaging at different stages of Alzheimer's disease 显示文摘 | Kadir A Almkvist O Forsberg A | 2012 | Neurobiol Aging2012，33，1： | 1 |
| 6 | Antioxidant properties ofpropofol and erythropoietin after closed head injury in rats显示文摘 | Ozturk E Demirbilek S Kadir But A | 2005 | ProgNeuroschopharmcol Bipsychiatry2005，29，6： | 1 |
| 7 | Comparison of different treatment methods for localized and generalized simple denture stomatitis 显示文摘 | Arikan A Kulak Y Kadir T | 1995 | Journal of Oral Rehabilization1995，22，5： | 1 |
| 8 | Antioxidant properties of propofol and erythropoietin after dosed head injury in rats 显示文摘 | Ozturk E Demirbilek S Kadir But A | 2005 | Prog Neuropsyehopharmaeol Biol Psychiatry2005，29，6： | 1 |
| 9 | Toxicity and electrophysiological effects of spilanthesacmell extract on Periplaneta americana显示文摘 | KADIR H A | 1989 | Pestic Sci1989，25，： | 1 |
| 10 | Target-specic PET probes for neurodegener-ative disorders related to dementia显示文摘 | Kadir A Nordberg A | 2010 | J Nucl Med2010，51，9： | 1 |
| 11 | Towards high-fidelity machining simu-lation显示文摘 | KADIR A A XU X | 2011 | Journal of Manufacturing Systems*2011，30，3： | 1 |
| 12 | Virtual machine toolsand virtual machining-A technological review显示文摘 | KADIR A A XU X HAMMERLE E | 2011 | Roboticsand Computer-Integrated Manufacturing2011，27，3： | 1 |
| 13 | Plasticized chi- tosan-PVA blend polymer electrolyte based proton battery 显示文摘 | Kadir M F Z Majid S R Arof A K | 2010 | J Electrochimica Acta2010，55，： | 1 |
| 14 | Color image encryption using skew tent map and hyper chaotic system of 6th-order CNN显示文摘 | Kadir A Hamdulla A Guo W Q | 2014 | Optik2014，5，： | 1 |
| 15 | Antioxidant properties of propofol and erythropoietin after closed head injury in rats显示文摘 | Ozturk E Demirbilek S Kadir But A | 2005 | Prog Neuroschopharmacol Biol Psychiatry2005，29，6： | 1 |
| 16 | Antifibrinolytic therapy with tranexamic acid in pregnancy and postpartum显示文摘 | PEITSIDIS P KADIR R A | 2011 | Expert Opin Pharmacother2011，12，4： | 1 |
| 17 | Single-chain variable fragments antibody specific to Corynespora cassiicola toxin,cassiicolin,reduces necrotic lesion formation in Hevea brasiliensis显示文摘 | Sunderasan E Kadir R A Pujade Renaud V | 2009 | J Gen Plant Pathol2009，75，： | 1 |
| 18 | The effects of partially substituting Indian carps or adding silver carp on polycul- tures including small indigenous fish species 显示文摘 | Milstein A Kadir A Wahab M A | 2008 | Aquaculture2008，279，： | 1 |
| 19 | Effect of ultrasound on the dissolution of colemanite in H2SO4 显示文摘 | OKUR H TEKIN T KADIR OZER A BA YRAMOGLU M | 2002 | Hydrometallurgy2002，67，： | 1 |
| 20 | Fractal geometry of the Sumatra active fault system and its geodynamical implications 显示文摘 | SUKMONO S ZEN M T KADIR W G A | 1996 | Journal of Geodynamics1996，22，12： | 1 |
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