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| 1 | 溶栓时间(入院到用药时间)的延迟及其对脑卒中治疗时间与预后的影响显示文摘尽管美国心脏协会/美国脑卒中协会关于脑卒中的治疗均提出了倡议,大量急性缺血性脑卒中患者仍然在到达就诊60min后才开始启动组织型纤溶酶原激活剂(阿替普酶)溶栓治疗。该研究旨在描述延迟的原因及其与患者预后之间的关系。 | 刘莉 叶鹏 Kamal N Sheng S Xian Y Matsouaka R Hill MD Bhatt DL Saver JL Reeves MJ Fonarow GC Schwamm LH Smith EE | 2017 | 中华高血压杂志2017,25,4: | 15 |
| 2 | Vitamin D in esophageal cancer: Is there a role for chemoprevention?显示文摘Vitamin D has emerged as a promising anti-cancer agent due to its diverse biological effects on tumor differentiation, apoptosis and suppression of cellular proliferation. Current evidence suggests a protective role of vitamin D in colon cancer. The effect of vitamin D on esophageal cancer remains controversial. Multiple studies investigated the association between vitamin D and esophageal cancer, employing different modes of assessment of vitamin D status such as serum 25-hydroxyvitamin D levels, vitamin D dietary intake or exposure to ultraviolet B(UVB) radiation. Genetic variations of the vitamin D receptor(VDR) gene and VDR expression in esophageal specimens have also been investigated. Ecological studies evaluating exposure to UVB radiation yielded an inverse correlation with esophageal cancer. When vitamin D dietary intake was assessed, direct association with esophageal cancer was observed. However, circulating 25-hydroxyvitamin D concentrations showed inconsistent results. In this review article, we present a detailed summary of the current data on the effects of vitamin D on various histological subtypes of esophageal cancer and their precursor lesions. Well-powered prospective studies with accurate measurement of vitamin D status are needed before chemoprevention with vitamin D is recommended, as current evidence does not support a chemopreventive role of vitamin D against esophageal cancer. Future studies looking at the incidence of esophageal cancer in patients with pre-cancerous lesions(Barrett's esophagus and squamous cell dysplasia) receiving vitamin D supplementation are needed. | Carol Rouphael Afrin Kamal Madhusudhan R Sanaka Prashanthi N Thota | 2018 | World Journal of Gastrointestinal Oncology2018,10,1: | 5 |
| 3 | Response of blood pressure after percutaneous transluminal renal artery angioplasty and stenting显示文摘AIM: To evaluate the short and intermediate term out-come of percutaneous transluminal renal artery angioplasty (PTRA) and stenting particularly on blood pressure (BP) control and renal function and to evaluate predictors of poor BP response after successful PTRA and stenting. METHODS: We conducted a prospective analysis of all patients who underwent PTRA and stenting in our institute between August 2010 to September 2012. A total number of 86 patients were underwent PTRA and renal stenting. Selective angiography was done to confirm at least 70% angiographic stenosis. The predilatation done except few cases with critical stenosis, direct stenting was done in the rest of cases. All patients received aspirin 325 mg orally, and clopidogrel 300 mg orally within 24 h before the procedure. Heparin was used as the procedural anticoagulant agent. Optimal results with TIMI-Ⅲ flow obtained in all cases. Following stent placement, aspirin 150 mg orally once daily was continued for a minimum of 12 mo and clopidogrel 75 mg orally once daily for at least 4 wk. The clinical, radiological, electrocardiography, echocardiography and treatment data of all patients were recorded. The BP measurement, serum creatinine and glomerular filtration rate (GFR) were recorded before the procedure and 1 and 6 mo after PTRA. RESULTS: A total of 86 patients were included in the study. The mean age of study population was 55.87±11.85 years old and 67 (77.9%) of patients were male. There was a significant reduction in both systolic and diastolic BP at 1 mo after the procedure: 170.15±20.10 mmHg vs 146.60±17.32 mmHg and 98.38±10.55 mmHg vs 89.88±9.22 mmHg respectively (P=0.0000). The reduction in BP was constant throughout the follow-up period and was evident 6 mo after the procedure: 144.23±18.19 and 88.26±9.79 mmHg respectively (P=0.0000). However, no improvement in renal function was observed at any time during the follow-up period. After multivariate analysis, we found male sex, low GFR (<60 mL/min) and higher baseline mean BP as a poor predictors of successful outcome on BP response after PTRA and stenting. CONCLUSION: The PTRA and stenting can be considered as an effective therapeutic intervention for improving BP control with minimal effect on renal function. The male sex, higher baseline BP and low GFR are associated with poor BP response after successful PTRA and stenting. | Jayesh S Prajapati Sharad R Jain Hasit Joshi Shaurin Shah Kamal Sharma Sibasis Sahoo Kapil Virparia Ashok Thakkar | 2013 | World Journal of Cardiology2013,5,7: | 3 |
| 4 | Imaging pancreatobiliary ductal system with optical coherence tomography: A review显示文摘An accurate, noninvasive and cost-effective method of in situ tissue evaluation during endoscopy would be highly advantageous for the detection of dysplasia or early cancer and for identifying different disease stages. Optical coherence tomography(OCT) is a noninvasive, high-resolution(1-10 μm) emerging optical imaging method with potential for identifying microscopic subsurface features in the pancreatic and biliary ductal system. Tissue microstructure of pancreaticobiliary ductal system has been successfully imaged by inserting an OCT probe through a standard endoscope operative channel. High-resolution OCT images and the technique's endoscopic compatibility have allowed for the microstructural diagnostic of thepancreatobiliary diseases. In this review, we discussed currently available pancreaticobiliary ductal imaging systems to assess the pancreatobiliary tissue microstructure and to evaluate varieties of pancreaticobiliary disorders and diseases. Results show that OCT can improve the quality of images of pancreatobiliary system during endoscopic retrograde cholangiopancheatography procedure, which may be important in distinguishing between the neoplastic and non-neoplastic lesions. | Mohammad S Mahmud Gray R May Mohammad M Kamal Ahmed S Khwaja Carry Sun Alex Vitkin Victor XD Yang | 2013 | World Journal of Gastrointestinal Endoscopy2013,5,11: | 2 |
| 5 | Melt rheology of polymer blends 显示文摘 | UTRACKI L A KAMAL M R | 1982 | Polymer Engineering and Science1982,22,: | 1 |
| 6 | Anodic electrosynthesis of cadmium selenide thin films-characterization and comparison with the passive/transpassive behavior of the CdX(X=S,Te) counterparts 显示文摘 | Kamal K Krishnan R | 1991 | J Electrchem Soc1991,138,1: | 1 |
| 7 | Resveratrol induces differentiation markers expression in anaplastic thyroid carcinoma via activation of Notch1 signaling and suppresses cell growth显示文摘 | Yu XM Jaskula-Sztul R Kamal A | 2013 | Mol Cancer Ther2013,12,7: | 1 |
| 8 | In vitro evolved non-aggregating and thermostable lipase:structural and thermodynamic investigation显示文摘 | Kamal M Z Ahmad S Molugu T R | 2011 | J Mol Biol2011,413,: | 1 |
| 9 | Intrauterine injection of human chorionic gonadotropin before embryo transfer significantly improves the implantation and pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection:a prospective randomized study显示文摘 | Mansour R Tawab N Kamal O | 2011 | Fertil Steril2011,96,: | 1 |
| 10 | Highperformance liquid chromatographic analysis of secoisolariciresinol diglucoside and hydroxycinnamic acid glucosides in flaxseed by alkaline extraction显示文摘 | Eliasson C Kamal Eldin A Andersson R | 2003 | Journal of Chromatography A2003,1012,: | 1 |
| 11 | Kinetics and thermal characterization of thermoset cure 显示文摘 | Kamal M R Sourour S | 1973 | Polym Eng Sci1973,13,1: | 1 |
| 12 | Morphological modeling of polymers solidification显示文摘 | Huang T Kamal R | 2000 | Polymer Engineering and Science2000,40,8: | 1 |
| 13 | Mechanical and microscopic investigation of whisker reinforced silicone rubber 显示文摘 | Weber M E Kamal M R | 1992 | Polymer Composites1992,13,2: | 1 |
| 14 | High Temperature Cyclic Oxidation and Hot Corro- sion Behaviours of SuperaUoys at 900 :C 显示文摘 | KAMAL S JAYAGANTHAN R PRAKASH S | 2010 | Bulle- tin of Materials Science2010,33,3: | 1 |
| 15 | Intrauterine injec- tion of human chorionic gonadotropin before embryo transfer signifi- cantly improves the implantation and pregnancy rates in in vitro fer- tifization/intracytoplasmic sperm injection: a prospective random- ized study显示文摘 | MANSOUR R TAWAB N KAMAL O | 2011 | Fertil Steril2011,96,6: | 1 |
| 16 | Thermostable Bacillus subtilis lipases:in vitro evolution and structural insight显示文摘 | Ahmad S Kamal M Z Sankaranarayanan R | 2008 | J Mol Biol2008,381,: | 1 |
| 17 | Optimal path computation for autono- mous aerial vehicles 显示文摘 | Samar R Kamal W A | 2012 | Cognitive Computation2012,4,4: | 1 |
| 18 | Intrauterine injection of hu-man chorionic gonadotropin before embryo transfer sig- nificantly improves the implantation and pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection: a pro- spective randomized study显示文摘 | Mansour R Tawab N Kamal O | 2011 | Fertil Steril2011,96,6: | 1 |
| 19 | 显示文摘 | Kamal M R | 1982 | Polym Eng Sci1982,22,: | 1 |
| 20 | Measurement and Calcu lation of Parison Dimensions and Bottle Distribution Du- ring Blow Molding 显示文摘 | Kamal M R Tan V Nalyond | 1981 | Polymer Engineering Science1981,21,: | 1 |