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| 1 | 原发性低密度脂蛋白胆固醇≥4.94mmol/L的男性降低低密度脂蛋白胆固醇对心血管病的影响显示文摘原发性低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)≥4.94mmol/L(190mg/dL)的患者由于长期暴露在显著升高的LDL-C下,心血管动脉粥样硬化的风险更高。因此,对于这些患者通常建议采用他汀类药物治疗,但是缺少随机试验证据支持。在该研究中,研究者提供了一些降低LDL-C对心血管病影响的初级预防资料。 | Vallejo-Vaz AJ Robertson M Catapano AL Watts GF Kastelein JJ Packard CJ Ford I Ray KK 黄洁 叶鹏 | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 2 | Swords into plowshares: IL-23 repurposes tumor immune surveillance显示文摘 | Langowski JL Kastelein RA Oft M | 2007 | Trends Immunol2007，28，5： | 1 |
| 3 | Diagnosis and treatment of familial hypercholesterolaemia 显示文摘 | Hovingh G K Davidson M H Kastelein J J P | 2013 | European heart journal2013，34，13： | 1 |
| 4 | AB-CG8 gene polymorphisms,plasma cholesterol concen-trations,and risk of cardiovascular disease in familial hypercholesterolemia 显示文摘 | Koeijvoets K C van der Net J B Dallinga-Thie G M Steyerberg E W Mensink R P Kastelein J J | 2009 | Atherosclerosis2009，204，： | 1 |
| 5 | Nevirap ine-containing antiretroviral therapy in HIV-1 infected patients results in an anti atherogenic lipid profile显示文摘 | Van der Valk M Kastelein JJ Murphy RL | 2001 | AIDS2001，15，18： | 1 |
| 6 | but the closely linked -629CA polymorphism and a novel promoter variant are independently associ ated with CETP concentration显示文摘 | KLERKX1 A H TANCK M W KASTELEIN J J Haplotype analysis of the CETP gene: not TaqIB | 2003 | Hum Mol Genet2003，12，： | 1 |
| 7 | The role of non- HDL cholesterol in risk stratification for coronary artery disease 显示文摘 | Rana J S Boekholdt S M Kastelein J J | 2012 | Curr Atheroscler Rep2012，14，2： | 1 |
| 8 | PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients显示文摘 | Leus FR Zwart M Kastelein JJ | 2001 | Atherosclerosis2001，154，： | 1 |
| 9 | PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients显示文摘 | Leus FR Zwart M Kastelein JJ | 2001 | Atherosclerosis2001，154，56： | 1 |
| 10 | Codon replacement in the PGK1 gene of Saccharomyees cerevisiae : experimental approach to study the role of biased co- don usage in gene expression显示文摘 | Hoekema A Kastelein R A Vasser M | 1987 | Mol Cell Biol1987，7，8： | 1 |
| 11 | Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterol- emia not adequately controlled with current lipid-lowering therapy: design and rationale of the ODYSSEY FH studies 显示文摘 | Kastelein JJ Robinson JG Faraier M | 2014 | Cardiovasc Drugs Ther2014，28，3： | 1 |
| 12 | Swords into plow- shares : IL - 23 repro'poses tumor immune surveillance显示文摘 | LANGOWSKI J L KASTELEIN R A OFT M | 2007 | Trends lmmunol2007，28，5： | 1 |
| 13 | C-reactive protein and cholesterol are equally strong predictors of cardiovascular risk and both are important for quality clinical care显示文摘 | RIDKER P M KASTELEIN J J GENEST J | | 0，，17： | 1 |
| 14 | Relationship between alirocumab, PCSK9 and LDL-C levels :results from the odyssey mono phase 3 trial of alirocumab 75 mg every 2 weeks 显示文摘 | Farnier M Kastelein J J P Roth E | 2014 | Atherosclerosis2014，235，2： | 1 |
| 15 | Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolemia not adequately controlled with current lipid-Lowering therapy: design and rationale of the ODYSSEY FH studies 显示文摘 | Kastelein J J Robinson J G Farnier M | 2014 | Cardiovasc Drugs Ther2014，28，3： | 1 |
| 16 | Comparison of atorvastatin 80 mg/day versus simvastatin 20 Lo 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering trial) 显示文摘 | Pedersen TR Cater NB Faergeman O Kastelein JJ Olsson AG Tikkanen M J Holme I Larsen ML Lindahl C Szarek M | 2010 | Am J Cardiol2010，106，3： | 1 |
| 17 | Lipids, apolipoproteins, and their ratios in re lation to cardiovascular events with statin treatment显示文摘 | Kastelein J J van der Steeg W A Holme I Gaffney M Cater N B Barter P | 2008 | Circulation2008，117，： | 1 |
| 18 | Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes 显示文摘 | Clee SM Kastelein JJ Van Dam M | 2000 | J Clin invest2000，106，10： | 1 |
| 19 | Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis显示文摘 | ATTIE A D KASTELEIN J P HAYDEN M R | 2001 | J Lipid Res2001，42，： | 1 |
| 20 | Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis显示文摘 | ATrlE A D KASTELEIN J P HAYDEN M R | 2001 | J Lip Res2001，42，11： | 1 |
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