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| 1 | The effects of Spirulina on anemia and immune function in senior citizens显示文摘Anemia and immunological dysfunction(i.e.immunosenescence)are commonly found in older subjects and nutritional approaches are sought to counteract these phenomena.Spirulina is a filamentous and multicellular bule-green alga capable of reducing inflammation and also manifesting antioxidant effects.We hypothesized that Spirulina may ameliorate anemia and immunosenescence in senior citizens with a history of anemia.We enrolled 40 volunteers of both sexes with an age of 50 years or older who had no history of major chronic diseases.Participants took a Spirulina supplementation for 12 weeks and were administered comprehensive dietary questionnaires to determine their nutritional regimen during the study.Complete cell count(CCC)and indoleamine 2,3-dioxygenase(IDO)enzyme activity,as a sign of immune function,were determined at baseline and weeks 6 and 12 of supplementation.Thirty study participants completed the entire study and the data obtained were analyzed.Over the 12-week study period,there was a steady increase in average values of mean corpuscular hemoglobin in subjects of both sexes.In addition,mean corpuscular volume and mean corpuscular hemoglobin concentration also increased in male participants.Older women appeared to benefit more rapidly from Spirulina supplements.Similarly,the majority of subjects manifested increased IDO activity and white blood cell count at 6 and 12 weeks of Spirulina supplementation.Spirulina may ameliorate anemia and immunosenescence in older subjects.We encourage large human studies to determine whether this safe supplement could prove beneficial in randomized clinical trials. | Carlo Selmi Patrick SC Leung Laura Fischer Bruce German Chen-Yen Yang Thomas P Kenny Gerry R Cysewski M Eric Gershwin | 2011 | Cellular & Molecular Immunology2011，8，3： | 2 |
| 2 | Joint factoranalysis versus eigenchannels in speaker recognition显示文摘 | Kenny P Boulianne G Ouellet P | 2007 | IEEE Transactions on Audio Speech and LanguageProcessing2007，15，4： | 1 |
| 3 | Eigenvoicemodeling with sparse training data显示文摘 | Kenny P Boulianne G Dumouchel P | 2005 | IEEETransactions on Speech and Audio Processing2005，13，3： | 1 |
| 4 | Exploration and development of Ceiba field, Rio Muni basin, Southern Equatorial Guinea 显示文摘 | Dailly P Lowry P Kenny G | 2002 | The Leading Edge2002，21，11： | 1 |
| 5 | Joint factor analysis versus eigenehannels in speaker recognition 显示文摘 | Kenny P Boulianne G Ouellet P | 2007 | IEEE Trans Audio Speech Lang Process2007，15，4： | 1 |
| 6 | Hirschsprung's disease显示文摘 | Kenny S E Tam P K H Garcia-Barcelo M | 2010 | Semin Pedlatr Surg2010，19，3： | 1 |
| 7 | Effects of heart rate on ventricular size, stroke volume, and output in the normal human fetus: a prospective Doppler echocardiographic study 显示文摘 | Kenny J Plappert T Doubilet P | 1987 | Circulation1987，76，1： | 1 |
| 8 | Joint factor analysis versus eigenchannels in speaker recognition显示文摘 | Kenny P Boulianne G Ouellet P | 2007 | IEEE Transactions on Audio Speech and Language Processing2007，15，4： | 1 |
| 9 | Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis显示文摘 | Kenny HA Leonhardt P Ladanyi A | 2011 | Clin Cancer Res2011，17，3： | 1 |
| 10 | Bone dowels in anterior lumbar interbody fusion显示文摘 | Lekovic G P Han P P Kenny K J Dickman C A | 2007 | J Spinal Disord Tech2007，20，： | 1 |
| 11 | Control of optical fiber taper shape显示文摘 | KENNY R P BIRKS T A OAKLEY K P | 1991 | Electronics Letters1991，27，18： | 1 |
| 12 | Reward, mechanisms in obesity:new insights and future directions 显示文摘 | KENNY P J | 2011 | Neuron2011，69，4： | 1 |
| 13 | Laparoscopic cholecystectomy in aute cholecystitis显示文摘 | Kenny P K Richard C T Levil D | 1996 | Arch Surg1996，131，5： | 1 |
| 14 | Speaker and session variability in GMM-based speaker verification显示文摘 | Kenny P Boulianne G Ouellet P | 2007 | IEEE Transactions on Audio Speech and Language Processing2007，15，4： | 1 |
| 15 | Control of a high-speed flywheel system for energy storage in space applications显示文摘 | Kenny B H Kascak P E Jansen R | 2005 | IEEE Transactions on Industry Applications2005，41，4： | 1 |
| 16 | Con- trol of a high-speed flywheel system for energy storage in space applications 显示文摘 | KENNY B H KASCAK P E JANSEN R | 2005 | IEEE Transaetions on Industry Applications2005，41，4： | 1 |
| 17 | Front-end factor analysis for speaker verification显示文摘 | Dehak N Kenny P Dehak R | 2010 | IEEE Trans Au- dio Speech Lang2010，19，4： | 1 |
| 18 | Transrectal ultrasound microbubble contrast angiography of the prostate显示文摘 | Ragde H Kenny G M Murphy G P | 1997 | Prostate1997，32，： | 1 |
| 19 | Storage conditions of avulsed teeth effect the pheno type of cultured human periodontal ligament cells显示文摘 | Lin DG Kenny DJ Lekic P | 2000 | J Periodont Res2000，35，1： | 1 |
| 20 | Effect of rapid and conventional cooling methods on the quality of cooked ham joints显示文摘 | Desmond E M Kenny T A Ward P | 2000 | Meat Science2000，56，3： | 1 |
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