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| 1 | 心力衰竭的诊断与评估显示文摘心力衰竭是常见的临床综合征,以呼吸困难、疲乏和容量超负荷为特点,也可出现外周性水肿及肺部哕音。心力衰竭有较高的发病率和病死率,尤其是老年人。许多疾病,如冠状动脉疾病(CAD)、高血压、瓣膜性心脏病和糖尿病均可引起或导致慢性心力衰竭的失代偿。40%~50%的心力衰竭患者为左心室功能保留的舒张性心力衰竭,其总病死率与收缩性心力衰竭相似。初始评估包括病史、体检、胸部X线片、心电图(ECG)和实验室评估,以识别原因或诱因。心尖移位、第三心音和胸部X线片显示静脉充血或间质水肿常有助于识别心力衰竭。 | 周淑新 朱翠明 King M Kingery JE Casey B | 2012 | 中国全科医学2012，15，36： | 38 |
| 2 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 3 | Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease显示文摘Mitochondrial dysfunction is known to be a contributing factor to a number of diseases including chronic alcohol induced liver injury. While there is a detailed understanding of the metabolic pathways and proteins of the liver mitochondrion, little is known regarding how changes in the mitochondrial proteome may contribute to the development of hepatic pathologies. Emerging evidence indicates that reactive oxygen and nitrogen species disrupt mitochondrial function through post-translational modifications to the mitochondrial proteome. Indeed, various new affinity labeling reagents are available to test the hypothesis that post-translational modification of proteins by reactive species contributes to mitochondrial dysfunction and alcoholic fatty liver disease. Specialized proteomic techniques are also now available, which allow for identification of defects in the assembly of multi-protein complexes in mitochondria and the resolution of the highly hydrophobic proteins of the inner membrane. In this review knowledge gained from the study of changes to the mitochondrial proteome in alcoholic hepatotoxicity will be described and placed into a mechanistic framework to increase understanding of the role of mitochondrial dysfunction in liver disease. | Sudheer K Mantena Adrienne L King Kelly K Andringa Aimee Landar Victor Darley-Usmar Shannon M Bailey | 2007 | World Journal of Gastroenterology2007，13，37： | 7 |
| 4 | Heterogeneity of the genome-linked protein of FMDV显示文摘 | King A M Q Anger T J R Brown F | 1980 | J Virol1980，34，： | 2 |
| 5 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://gffzz783b6e01a04243c3hcon9kq5okb5x6pv0.ffgz.tsg.suse.edu.cn/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016，3，1： | 2 |
| 6 | phenomena of scintillation noise in radar-tracking system显示文摘 | Dunn J H Howard D D king A M | 1959 | Proceedings of IRE1959，47，5： | 1 |
| 7 | Usefulness of ovarian volume and cysts in female is osexual precocbus puberty 显示文摘 | KING L R SIEGE I M J SOBMON A L | 1993 | J Ultrasound in Medicine1993，12，10： | 1 |
| 8 | Circulating Ly-6C + myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease显示文摘 | King I L Dickendesher T L Segal B M | 2009 | Blood2009，113，14： | 1 |
| 9 | SchrSdinger cat superposition state of an atom 显示文摘 | Monroe C Meekhof D M King B E | 1996 | Science1996，272，： | 1 |
| 10 | Anthocyanin, phenolic composition, colour measurement and sensory analysis of BC commercial red wines显示文摘 | CLIFF M A KING M C SCHLOSSER J | 2007 | Food Research International2007，40，1： | 1 |
| 11 | Recent developments in acute myelogenous leukemia therapy 显示文摘 | King M E Rowe J M | 2007 | Oncologist2007，12，2： | 1 |
| 12 | Assembly of foot-and- mouth disease virus empty capids synthesized by a vaccinia virus expression system显示文摘 | Abrams C C King A M Belsham G J | 1995 | J Gen Virol1995，76，： | 1 |
| 13 | Experimental studies of elastic-wave propagation in a columnar-jointed rock mass显示文摘 | King M S Myer L R Rezowalli J J | 1986 | Geophysical Prospecting1986，34，8： | 1 |
| 14 | A search of the missing carbon sink:a model of terrestrial biospheric response to landuse change and atmospheric CO2显示文摘 | King A W Emanuel W R Wullschleger S D and Post W M | 1995 | Tellus1995，47，： | 1 |
| 15 | An Energy-based formulation for computing nonlinear normal modes in undamped continuous systems显示文摘 | King M E Vakakis A F | 1994 | Transactions of the ASME Journal of Vibration and Acoustics1994，11，6： | 1 |
| 16 | Purification and characterization of a thermostable α - galactosidase from Thermoanaerobacterium polysaccharolyticum显示文摘 | King M R White B A Blaschek H P Chassy B M Mackie R I Cann I KO | 2002 | Journal of Agricultural and Food Chemistry2002，50，： | 1 |
| 17 | Generation of Nonclassical Motional States of a Trapped Atom 显示文摘 | MEEKHOF D M MONROE C KING B E | 1996 | Phys Rev Lett1996，76，： | 1 |
| 18 | Absorptive form-factors for high- energy electron-diffraction 显示文摘 | Bird D M King Q A | 1990 | Acta Crystallographica Section A1990，46，： | 1 |
| 19 | A rapid and efficient non-radioactive method for screening recombinant DNA libraries 显示文摘 | Amaravadi L King M W | 1994 | Biotechniques1994，16，1： | 1 |
| 20 | Identification of a Linear Peptide Recognized by Monoclonal Antibody 2D7 Capeble of Generating CCR5-Specific Antibodies with Human Immunodeficiency Virus-Neutralizing Activity 显示文摘 | Khurana S Kennedy M King LR | 2005 | JOURNAL OF VIROLOGY2005，，： | 1 |
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