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| 1 | 星形胶质细胞和嗅鞘细胞之间的Panglial缝隙连接介导Ca^(2+)瞬变的传递和神经血管耦合显示文摘星形胶质细胞排列在有高度组织性的缝隙连接耦合网络中,通过Ca^(2+)波的传播进行通信。星形胶质细胞不仅与邻近的星形胶质细胞结合,而且还与少突胶质细胞偶联,形成panglial合胞体。但panglial合胞体中的神经胶质细胞是否通过Ca^(2+)信号传递信息尚不清楚。我们使用共聚焦Ca^(2+)成像来研究小鼠嗅球中星形胶质细胞和嗅鞘神经胶质细胞(OECs)之间的细胞间通讯。研究结果表明,通过'笼状' ATP和'笼状' tACPD的局部光解可引起的肾小球旁星形胶质细胞中的Ca^(2+)瞬变,导致OEC中随之而来的Ca^(2+)反应。这种从星形胶质细胞到OEC的Ca^(2+)反应的传递在神经元抑制的情况下持续存在,但是当用甘珀酸抑制缝隙连接偶联时消失。当通过DHPG的抽吸在OEC中直接诱发Ca^(2+)瞬变时,它们导致肾小球星形胶质细胞中的Ca^(2+)反应延迟,表明Ca^(2+)信号的panglial传递以双向方式发生。此外,从星形胶质细胞到OEC的Ca^(2+)信号的panglial传递导致嗅觉神经层中OEC相关血管的收缩。本研究结果证明了在缝隙连接耦合的panglial网络中,不同类别的神经胶质细胞之间通过Ca^(2+)进行信号传递,并借此调节嗅球中血管的直径。 | Beiersdorfer A Scheller A Kirchhoff F Lohr C 聂昊 | 2019 | 神经损伤与功能重建2019，14，3： | 2 |
| 2 | Conduction disturbances and increased atrial vulnerability in connexin40-deficient mice analyzad by transesophageal stimulation显示文摘 | Hagendorff A Schumacher B Kirchhoff S | 1999 | Circulation1999，99，： | 2 |
| 3 | Differential sensitivity of human papillomavirus type 16 (+)and type 18 (+) cervical carcinoma cells to CD95 mediated apoptosis 显示文摘 | Aguilar Lemarroy A Kirchhoff S Whitaker N | 2001 | Int J Cancer2001，93，6： | 1 |
| 4 | Combining acoustic and articulatory feature information for robust speech recognition 显示文摘 | Kirchhoff K Fink G A Sagerer G | 2002 | Speech Communication2002，37，3： | 1 |
| 5 | Differentiating market strategies for disruptive technologies显示文摘 | Walsh S T Kirchhoff B A Newbert S | 2002 | IEEE Transactions on Engineering Management2002，49，11： | 1 |
| 6 | Differential sensitivity of human papillomavirus type 16(+) and type 18(+) cervical Carcinoma cells to CD95-mediated apoptosis显示文摘 | Aguilar Lemarroy A Kirchhoff S Whitaker N | 2001 | Inj Cancer2001，93，6： | 1 |
| 7 | Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion 显示文摘 | Kirchhoff K Machicao F Haupt A | 2008 | Diabetologia2008，51，4： | 1 |
| 8 | Role of the intra-arterial calcium stimulation test in the preoperative localization of insulinomas显示文摘 | Chavan A Kirchhoff TD Brabant G | 2000 | Eur Radiol2000，10，： | 1 |
| 9 | Differentiating Market Strategies for Disruptive Technologies 显示文摘 | Steven T Bruce A Kirchhoff and Scott Newber | 2002 | IEEE Transactions on Engineer- ing Management2002，49，4： | 1 |
| 10 | Organization effectiveness measurement and policy research 显示文摘 | Kirchhoff B A | 1997 | Academy of Management Re- view1997，2，3： | 1 |
| 11 | Conduction disturbances and increased atrial vulnerability in Connexir40-deficient mice analyzed by transesophageal stimulation显示文摘 | Hagendorff A Schumacher B Kirchhoff S | 1999 | Circulation1999，99，： | 1 |
| 12 | Resting mieroglial cells are highly dynamic surveillants of brain parenchyma in vivo 显示文摘 | Nimmerjahn A Kirchhoff F Helmchen F | 2005 | Science2005，308，： | 1 |
| 13 | Conduction disturbances and increased atrial vulnerability in connexin 40-deficient mice analyzed by transesophageal stimulation显示文摘 | Schumacher B Kirchhoff S | 1999 | Circulation1999，99，： | 1 |
| 14 | The effect of firm formation and growth on job cordially, reation in the United States显示文摘 | KIRCHHOFF BRUCE A PHILLIPS BRUCE D | 1988 | Journal of Business Venturing1988，3，4： | 1 |
| 15 | Intraosseous infusionfor adults 显示文摘 | Leidel B A Kirchhoff C | 2008 | Chirurg2008，79，4： | 1 |
| 16 | Effects of cell concentration and growth period on articular and ear chondrocyte transplants for tissue engineering显示文摘 | Panossian A Ashiku S Kirchhoff CH | 2001 | Plast Reconstr Surg2001，108，2： | 1 |
| 17 | NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes显示文摘 | Lalo U Pankratov Y Kirchhoff F North RA Verkhratsky A | 2006 | J Neurosci2006，26，10： | 1 |
| 18 | A Value Creation of Measuring and Managing the R&D Portfolio 显示文摘 | Bruce A Kirchhoff Matthias J Merges | 2001 | Engineering Management Journal2001，，13： | 1 |
| 19 | Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice显示文摘 | NELLES E HAGENDORFF A | 1998 | Curr Biol1998，8，： | 1 |
| 20 | Washington State cancer patients found to be at greater risk for bankruptcy than people without a cancer diagnosis显示文摘 | Ramsey S Blough D Kirchhoff A | 2013 | Health Aff (Millwood)2013，32，6： | 1 |
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