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| 1 | 在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。 | McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) | 2021 | 中华高血压杂志2021，29，5： | 15 |
| 2 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 3 | A low-glycemic index diet combined with exercise reduces insulin resistance,postprandial hyperinsulinemia,and glucose-dependent insulinotropic polypeptide responses in obese,prediabetichumans显示文摘 | Solomon T P Haus J M Kelly K R | 2010 | Am J Clin Nutr2010，92，6： | 1 |
| 4 | Robust analysis of the yeast proteome under 50 kDa by molecular-massbased fractionation and top-down mass spectrometry显示文摘 | Kellie J F Catherman A D Durbin K R Tran J C Tipton J D Norris J L Witkowski C E 2nd Thomas P M Kelleher N L | | 0，，01： | 1 |
| 5 | Late paleocene to eocene paleocenography of the equatorial pacific ocean: stable isotopes recorded at ocean drilling program site 865, allison guyot显示文摘 | Zachos J C Thomas E Parrow M Paul C K Kelly D C Silva I P Sliter W V Lohmann K C | 1995 | Paleoceanography1995，10，： | 1 |
| 6 | Chains and networks,territories and scales:towards a relational framework for analyzing the global economy显示文摘 | Dicken P Kelly P Olds K | 2001 | Global Network2001，1，2： | 1 |
| 7 | 3-D prestack reverse-time depth migration applied to vertical cableseismic data显示文摘 | Shen Y Valasek P Kelly K etal | 2000 | Expanded Abstracts of 70^th Annual Internat SEG Mtg2000，，： | 1 |
| 8 | Long-term outcome related to epidermal growth factor receptor status in bladder cancer 显示文摘 | Mellon K Wright C Kelly P | 1995 | J Urol1995，153，3： | 1 |
| 9 | Interface resistance of disordered magnetic multilayers显示文摘 | Xia K Kelly P J Bauer G E W | 2001 | Phys Rev2001，63，64： | 1 |
| 10 | Type interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (Pristane)显示文摘 | Nacionales D C Kelly K M Lee P Y | 2006 | AM J Pathol2006，168，4： | 1 |
| 11 | Rate control for communication networks: shadow price, proportional fairness and stability显示文摘 | KELLY F P MAULLOO K A TAN H D K | 1998 | Journal of the Operational Re- search Society1998，49，3： | 1 |
| 12 | Chains and Networks,Territories and Scales:Towards a Relational Framework for Analyzing the Global Economy显示文摘 | DICKEN P KELLY P F OLDS K etal | 2001 | Global Networks2001，8，： | 1 |
| 13 | Slow responses to standard dose rituximab in immune thrombocytopenic purpura显示文摘 | KELLY K GLEESON M MURPHY P T | 2009 | Haematologica2009，94，： | 1 |
| 14 | Induction of apoptosis by mitomycin- C in an ex vivo model of bladder cancer显示文摘 | KELLY J D WILLAMSON K E WEIR H P | 2000 | BIU Intern2000，85，2： | 1 |
| 15 | Randomized phase l]I trial of paelitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small -cell lung cancer: a Southwest Oncology Group trial 显示文摘 | Kelly K Crowley J Burro P A Jr | 2001 | J Clin Oncol2001，19，13： | 1 |
| 16 | Identifying, understanding, and analyzing critical infrastructure interdependencies 显示文摘 | RINALDI S M PEERENBOOM J P KELLY T K | 2001 | IEEE Control Systems Magazine2001，21，6： | 1 |
| 17 | Duration of breast milk expression among working mothers enrolled in an employer-sponsored lactation program显示文摘 | Ortiz J McGilligan K Kelly P | 2004 | Pediatr Nurs2004，30，2： | 1 |
| 18 | Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction显示文摘 | Khan S Q Ng K Dhillon O Kelly D Quinn P Squire I B | 2009 | Eur Heart J2009，30，： | 1 |
| 19 | Slow responses to standard dose rituximab in immune thrombocytopenic purpura显示文摘 | Kelly K Gleeson M Murphy P T | 2009 | Haematologica2009，94，3： | 1 |
| 20 | The intention of advanced prac- tice registered nurses to remain in positions at family planning clinics serving low-income women显示文摘 | Cheng AL Kelly P J Carlson K | 2014 | J Prof Nurs2014，30，1： | 1 |
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