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315篇 您的检索式:作者名="Kelly P L"
    题名 作者 年代 出处 被引量
1在血压控制不良的高血压患者中使用数字化干预的家庭和在线血压管理:随机对照试验显示文摘HOME BP试验(The home and online management and evaluation of blood pressure)的目的是评估在初级预防中结合自我监测和自我管理的数字化干预在高血压管理中的作用。研究者纳入英国76个治疗中心经过治疗但血压控制不好(>140/90 mm Hg, 1 mm Hg=0.133 kPa)并能上网的患者622例,进行自动确定主要终点的公开随机对照试验。McMa-nus RJ Little P Stuart B Morton K Raftery J Kelly J Bradbury K Zhang J Zhu S Murray E May CR Mair FS Michie S Smith P Band R Ogburn E AllenJ Rice C Nut-tall J Williams B Yardley L 陈嘉睿(译) 叶鹏(审校) 2021中华高血压杂志2021,29,5:15
2Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D 2013MMWR. Morbidity and Mortality Weekly Report2013,,18:3
3Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS.Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight 2010Cellular & Molecular Immunology2010,7,3:3
4GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories 显示文摘Jacobson L H Kelly P H Bettler B 2006J Neurosci2006,26,34:1
5Ultrafine gained ferrite formed by interrupted hottorsion of plain carton steel显示文摘Kelly G L Beladi H Hedgson P 2002ISIJ International2002,42,12:1
6Robust analysis of the yeast proteome under 50 kDa by molecular-massbased fractionation and top-down mass spectrometry显示文摘Kellie J F Catherman A D Durbin K R Tran J C Tipton J D Norris J L Witkowski C E 2nd Thomas P M Kelleher N L 0,,01:1
7Identification of XAF1 as an antagonist of XIAP anti-Caspase activity显示文摘LISTON P FONG W G KELLY N L 2001Nat Cell Biol2001,3,2:1
8The Characterization ofOxotremorine induced Hypothermic Response in the Rat 显示文摘Ryan P M Kelly J P Chambers P L 1996Pharmacol Toxicol1996,79,5:1
9查看详情显示文摘Regan S P Marozas J A Craxton R S Kelly J H Donaldson W R Jaanimagi P A Jacobs-Perkins D Keck R L Kessler T J Mey-erhofer D D Sangster T C Seka W Smalyuk V A Sknpsky S Zuegel J D 0,,:1
10Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cy- tokine profiles 显示文摘D'Mahony L McCarthy J Kelly P 2005Gastroenterology2005,128,3:1
11Selective detection,enumeration and identification of potentially probiotic Lactobacillus and Bifidobacterium species in mixed bacterial populations显示文摘CHARTERIS W P KELLY P M MORELLI L 1997International Journal of Food Microbiology1997,35,1:1
12Classification comparisons between dual-pol,compact polarimetric and quad-pol SAR imagery显示文摘Ainsworth T L Kelly J P Lee J S 2009ISPRS Journal of Photogrammetry and Remote Sensing2009,64,5:1
13Influence of transglutaminase treatment on some physico-chemical properties of milk 显示文摘O' Sullivan M M Kelly A L Fox P F 2002Dairy Research2002,69,:1
14Preferential flow and transport ofnitrate and bromide in clay pan soil 显示文摘Kelly B P Pomes M L 1998Ground Water1998,36,48:1
15Effects of high-pressure and heat treatments on physical and biochemicalcharacteristics of oysters (Crassostrea gigas)显示文摘Cruz-Romero M Kelly A L Kerry J P 2007InnovativeFood Science and Emerging Technologies2007,,8:1
16Antibiotic suscep- tibility of potentially probiotic Lactobacillus species显示文摘CHARTERIS W P KELLY P M MORELLI L 1998J Food Protect1998,61,12:1
17Selective Detection, Enumeration and Identification of Potentially Probiotic Lactobaeillus and Bifidobacterium Species in Mixed Bacterial Populations 显示文摘CHARTERIS W P KELLY P M MORELLI L 1997International Journal of Food Microbiology1997,35,1:1
18Fatty acids, volatile compounds and colour changes in high-pressure-treated oysters ( Crassostrea gigas ) 显示文摘CRUZ-ROMERO M C KERRY J P KELLY A L 2008Innovat Food Sci Emerg Tech2008,9,1:1
19Preliminary studies for the differentiation of apple juice samples by chemometric analysis of solid-phase microextraction-gas chromatographic data显示文摘Reid L M Colm P 0 D Kelly J D 2004Journal of Agricultural and Food Chemistry2004,52,23:1
20Fatty acids, volatile compounds and colour changes in high-pressure-treated oysters (Crassostrea gigas) 显示文摘Cruz-Romeroa M C Kerrya J P Kelly A L 2008Innovative Food Science & Emerging Technologies2008,9,1:1
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