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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Behavior and design of reinforced concrete, steel, and steel-concrete coupling beams显示文摘 | KENT A HARRIES M EERI BINGNIAN GONG BAHRAM M SHAHROOZ | 2000 | Earthquake Spectra2000，16，4： | 1 |
| 4 | Definiing regions of the Y - chromosome responsible for male infertility and identification of a fourth AZF region (AZFd) by Y - chromosome microdeletion detection显示文摘 | Kent - First M Muallem A SchultzJ | 1999 | Mol Reprod Dev1999，53，： | 1 |
| 5 | Defining regionsof the Yechromosome responsible formale infertility and identification of a fourthAZFregion(AZFd) by Y chromo some micro deletion detection显示文摘 | Kent First M Muallem A Shuhz J | 1999 | MolReprod Dev1999，53，1： | 1 |
| 6 | Mississippian Barnett Shale,Fort Worth basin,north-central Texas:Gas-shale play with multi-trillion cubic foot potential显示文摘 | Scott L Montgomery Daniel M Jarvie Kent A Bowker | | 0，，02： | 1 |
| 7 | Defining regions of the Y chromosome responsible for male infertility and identification of afourth AZF region (AZFd) by Y chromosome microdeletion detection 显示文摘 | Kent - First M Muallem A Shultz J | 1999 | Mol Rep rod Dev1999，53，1： | 1 |
| 8 | Full polarimetric calibration for radar cross-section measurements:Performance analysis显示文摘 | Welsh B M Kent B M Buterbaugh A L | 2004 | IEEE Trans on AP2004，52，9： | 1 |
| 9 | Brain oedema in focal ischaemia:molecular pathophysiology and theoretical implications显示文摘 | Simard J M Kent T A Chen M | 2007 | Lancet Neurol2007，6，3： | 1 |
| 10 | The assessment of marine stock enhancement in Southem Califomia:a case study involving dle white eabass显示文摘 | KENT D B | 1995 | American Fisheries Society Symposium1995，，： | 1 |
| 11 | A structured model for penicillin production on mixed substrates显示文摘 | PAUL G C SYDDALL M T KENT C A | 2001 | Biochemical Engineering Journal2001，7，： | 1 |
| 12 | Mississippi- an Barnett Shale, Fort Worth Basin, north central Texas: Gas-shale play with multi-trillion cubic foot potential显示文摘 | SCOTT L M DANIEL M J KENT A B | 2005 | AAPG Bulletin2005，89，2： | 1 |
| 13 | Virtual reference wet-lands for assessing wild wife显示文摘 | KENT D M SCHWEGLER B R LANGSTON M A | 1999 | Florida Scientist1999，62，： | 1 |
| 14 | The Russel - Yasuda Kasai model : an asset/liability model for a Japanese insurance company using multi - stage stochastic programming 显示文摘 | Carino D R Kent T Mayers D H Stacy C Sylvanus M Turner A Watanabe K Ziemba W T | 1994 | Interfaces1994，24，： | 1 |
| 15 | Brain oedema in focal ischaemia:molecular pathophysiology and theoretical implica- tions显示文摘 | Simard J M Kent T A Chen M | 2007 | Lancet Neurol2007，6，3： | 1 |
| 16 | Prospective highlights of functional skin proteomics显示文摘 | Huang C M Elmets C A Kampen kent R V | | 0，，： | 1 |
| 17 | STEP(satellite test of the equivalence principle)显示文摘 | Sumner T J Anderson J Blaser J P Cruise A M Damour T Dittus D Everitt C W F Fou-lon B Jafry Y Kent B J Lockerbie N Loeffler F Mann G Mester J Pegrum C ReinhardtR Sandford M Scheicher A Speake C C Torii R Theil S Touboul P Vitale S Vodel W Worden P W | 2007 | Advance in Space Re-search2007，39，2： | 1 |
| 18 | Urban plant ecology patterns and processes :A case study of the flora of the city of Plymouth显示文摘 | KENT M STEVEN R A ZHANG L | 1999 | Journal of Biogeography1999，26，6： | 1 |
| 19 | Knowledge acquisition from foreign parents in international joint ventures: An empirical study in Vietnam显示文摘 | PHAN T A BAUGHN C C NGO T M H KENT E N | 2006 | International Business Review2006，，15： | 1 |
| 20 | Full Polarimetric Calibration for Radar Cross-Section Measurements:Performance Analysis显示文摘 | Welsh B M Kent B M Buterbaugh A L | 2004 | IEEE Trans on AP2004，52，9： | 1 |
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