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38篇 您的检索式:作者名="Koerts T"
    题名 作者 年代 出处 被引量
1Apoptolidin: Induction of apoptosis by a natural product 显示文摘DANIEL P T KOERT U SCHUPPAN J 2006Chem lnt Ed2006,45,6:1
2Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
3Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
4Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
5Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
6Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscess显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
7Use of diffusion- weighted MR imaging in differential diagnosis between intrac- erebral necrotic tumors and cerebral abscesses 显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,:1
8Human macrophages primed with angiogenic factors show dynamic plasticity, irrespective of extracellular matrix components 显示文摘Ploeger D T van Putten S M Koerts J A 2012Immunobiology2012,217,3:1
9Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses 显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,:1
10Use of diffusion- weighted MR imaging in the differential diagnosis between intracerebral necrotic tumors and cerebral abscesses 显示文摘Desprechins B Stadnik T Koerts G 1999AJNR Am J Neuroradiol1999,20,12:1
11Use of diffusion weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999Am J Neuroradiol1999,20,7:1
12Use of diffusion- weighted MR imaging in differential diagnosis between irtrac- erebral necrotic tumors and cerebral abscesses 显示文摘Desprechins B Stadnik T Koerts G et a/ 1999AJNR Am J Neuroradiol1999,20,7:1
13Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999Am J Neuroradiol1999,20,7:1
14Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
15Machanisms of High-Copy-numberIntegrationofpMIRY-Type Vectors Into the Ribosomal DNA of Saccharomyces Cerevisiae显示文摘LOPES T S HAKKAART G KOERTS B L 1991Gene1991,105,1:1
16Use ot diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses 显示文摘Desprechins B Stadnik T Koerts G 1999AJNR Am J Neuroradiol1999,20,:1
17Use of Diffusion-weighted MR Imaging in Differential Diagnosis Between Intracerebral Necrotic Tumors and Cerebral Abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,7:1
18Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR1999,20,:1
19Ex-vivo evaluation of gene therapy vectors in human pancreatic (cancer) tissue slices显示文摘AIM:To culture human pancreatic tissue obtained from small resection specimens as a pre-clinical model for examining virus-host interactions. METHODS:Human pancreatic tissue samples (malignant and normal)were obtained from surgical specimens and processed immediately to tissue slices. Tissue slices were cultured ex vivo for 1-6 d in an incubator using 95%O2.Slices were subsequently analyzed for viability and morphology.In addition the slices were incubated with different viral vectors expressing the reporter genes GFP or DsRed. Expression of these reporter genes was measured at 72 h after infection.RESULTS:With the Krumdieck tissue slicer,uniform slices could be generated from pancreatic tissue but only upon embedding the tissue in 3%low melting agarose.Immunohistological examination showed the presence of all pancreatic cell types.Pancreatic normal and cancer tissue slices could be cultured for up to 6 d,while retaining viability and a moderate to good morphology.Reporter gene expression indicated that the slices could be infected and transduced efficiently by adenoviral vectors and by adeno associated viral vectors,whereas transduction with lentiviral vectors was limited.For the adenoviral vector,the transduction seemed limited to the peripheral layers of the explants. CONCLUSION:The presented system allows reproducible processing of minimal amounts of pancreatic tissue into slices uniform in size,suitable for pre-clinical evaluation of gene therapy vectors.Michael A van Geer Koert FD Kuhlmann Conny T Bakker Fibo JW ten Kate Ronald PJ Oude Elferink Piter J Bosma 2009World Journal of Gastroenterology2009,15,11:1
20Use of diffusion-weighted MR imaging in differential diagnosis between intracerebral necrotic tumors and cerebral abscesses显示文摘Desprechins B Stadnik T Koerts G 1999AJNR Am J Neuroradiol1999,20,7:1
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