|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Soy-based renoprotection显示文摘Chronic kidney disease(CKD) is a significant publich ealth problem as risk factors such as advanced age, obesity, hypertension and diabetes rise in the global po-pulation. Currently there are no effective pharmacologic treatments for this disease. The role of diet is important for slowing the progression of CKD and managing symptoms in later stages of renal insufficiency. While low protein diets are generally recommended, maintaining adequate levels of intake is critical for health. There is an increasing appreciation that the source of protein may also be important. Soybean protein has been the most extensively studied plant-based protein in subjects with kidney disease and has demonstrated renal protective properties in a number of clinical studies. Soy protein consumption has been shown to slow the decline in estimated glomerular filtration rate and significantly improve proteinuria in diabetic and non-diabetic patients with nephropathy. Soy's beneficial effects on renal function may also result from its impact on certain phy-siological risk factors for CKD such as dyslipidemia, hypertension and hyperglycemia. Soy intake is also associated with improvements in antioxidant status and systemic inflammation in early and late stage CKD pati-ents. Studies conducted in animal models have helped to identify the underlying molecular mechanisms that may play a role in the positive effects of soy protein on renal parameters in polycystic kidney disease, metabolically-induced kidney dysfunction and age-associated prog-ressive nephropathy. Despite the established relationship between soy and renoprotection, further studies are needed for a clear understanding of the role of the cellular and molecular target(s) of soy protein in main-taining renal function. | Nancy J Mc Graw Elaine S Krul Elizabeth Grunz-Borgmann Alan R Parrish | 2016 | World Journal of Nephrology2016，5，3： | 5 |
| 2 | Acute heart failure in elderly patients:a review of invasive and non-invasive management显示文摘Acute heart failure(AHF)is a major cause of unplanned hospitalisations in the elderly and is associated with high mortality.Its prevalence has grown in the last years due to population aging and longer life expectancy of chronic heart failure patients.Although international societies have provided guidelines for the management of AHF in the general population,scientific evidence for geriatric patients is often lacking,as these are underrepresented in clinical trials.Elderly have a different risk profile with more comorbidities,disability,and frailty,leading to increased morbidity,longer recovery time,higher readmission rates,and higher mortality.Furthermore,therapeutic options are often limited,due to unfeasibility of invasive strategies,mechanical circulatory support and cardiac transplantation.Thus,the in-hospital management of AHF should be tailored to each patient's clinical situation,cardiopulmonary condition and geriatric assessment.Palliative care should be considered in some cases,in order to avoid unnecessary diagnostics and/or treatments.After discharge,a strict follow-up through outpatient clinic or telemedicine is can improve quality of life and reduce rehospitalisation rates.The aim of this review is to offer an insight on current literature and provide a clinically oriented,patient-tailored approach regarding assessment,treatment and follow-up of elderly patients admitted for AHF. | Gregorio Tersalvi Alessio Gasperetti Marco Schiavone Jeroen Dauw Cecilia Gobbi Marialessia Denora Joel Daniel Krul Giacomo Maria Cioffi Gianfranco Mitacchione Giovanni B.Forleo | 2021 | Journal of Geriatric Cardiology2021，18，7： | 4 |
| 3 | Thoracoscopic video-assisted pulmonary vein antrum isolation, ganglionated plexus ablation, and periprocedural confirmation of ablation lesions: first results of a hybrid surgical-electrophysiological approach for atrial fibrillation显示文摘 | Krul SP Driessen AH van Boven W J | 2011 | Circ Arrhythm Electrophysiol2011，4，3： | 1 |
| 4 | HLA and susceptibility to cervical neoplasia显示文摘 | Krul EJ Schipper RF Schreuder GM | 1999 | Hum Immunol1999，60，4： | 1 |
| 5 | Increased breast cancer risk in in vitro fertilisation treated women with a multiple preg- nancy= A new hypothesis based on historical in vitro fertilisation treatment data显示文摘 | Krul IM Groeneveld E Spaan M | 2015 | Eur J Cancer2015，51，1： | 1 |
| 6 | The influence of NOx on the oxidation of metal activated diesel soot 显示文摘 | Jelles S J Krul R R Makkee M | 1999 | Catalysis Today1999，53，： | 1 |
| 7 | HLA and susceptibility to cervical neoplasia显示文摘 | Krul EJT Schipper RF Schreuder GM | 1999 | Hum Immunol1999，60，4： | 1 |
| 8 | Metabolism of sinigrin(2-P ropenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large Intestinal mode 显示文摘 | Cyrille Krul Christe l e Humblot Catherine Philippe | 2002 | Carcinogenesis2002，23，6： | 1 |
| 9 | Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling显示文摘 | Verwei M van Burgsteden J A Krul C A | 2006 | Toxicol Lett2006，165，： | 1 |
| 10 | Mechanical properties of graft copolymers of polyethylene and acrylonitrile obtained by the inhibited graft polymerization method显示文摘 | Krul L P Matusevich Yu I | 1984 | Journal of Polymer Science Polymer Letters Edition1984，22，11： | 1 |
| 11 | Nutrient physiology, metabolism, and nutrient-nutrient interactions of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3,4-dihydroxyphenylacetic acid has antiproliferative activity显示文摘 | Kun Gao Anlong Xu Cyrille Krul | 2006 | The Journal of Nutrition2006，136，1： | 1 |
| 12 | The significance of the aerobic-anaerobic transition for the determination of workload intensities during endurance training显示文摘 | Kindermann W Simon G Krul J | 1979 | Eur J Appl Physiol1979，，42： | 1 |
| 13 | Analysis of urinary caffeine metabolites to assess biotransformation enzyme activities by reversed-phase high-performance liquid chromatography显示文摘 | Krul C Hageman G | 1998 | J Chromatogr B Biomed Sci Appl1998，709，1： | 1 |
| 14 | Performance comparison of protein A affinity resins for the purification of monoclonal antibodies 显示文摘 | Swinnen K Krul A Van Goidsenhoven IV | 2007 | J Chromatogr B Analyt Technol Biomed Life Sci2007，848，1： | 1 |
| 15 | Production of Clean Transportation Fuels and Lower Olefins from Fischer- Tropsch Synthesis Waxes Under Fluid Catalytic Cracking Con- ditions显示文摘 | Dupain X Krul R A Schaverien C J | 2006 | ApplCatal B2006，63，11： | 1 |
| 16 | HLA and susceptibility to cervical neoplasia显示文摘 | Krul EJ Schipper RF Schreuder GM | 1999 | J Hum Immunol1999，60，4： | 1 |
| 17 | Water super absorbents based on copolymers of acrylamide with sodium acrylate显示文摘 | Krul L P Nareiko E I Matusevich YuI | 2000 | Polymer Bulletin2000，45，2： | 1 |
| 18 | Using genetic variation to optimize nutritional preemption显示文摘 | Gillies P J Krul E S | 2007 | J Nutr2007，137，1： | 1 |
| 19 | Different profiles of allelic losses in cervical carcinoma cases in Surinam and the Netherlands显示文摘 | Krul EJ Kersemaekers AM Zomerdi Jk Nooyen YA | | 0，，： | 1 |
| 20 | Metabolism of sinigrin(2-P ropenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large Intestinal mode显示文摘 | Cyrille Krul Christe le Humblot Catherine Philippe | 2002 | Carcinogenesis2002，23，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员