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212篇 您的检索式:作者名="Kuipers W"
    题名 作者 年代 出处 被引量
1Angiogenic markers endoglin and vascular endothelial growth factor in gastroenteropancreatic neuroendocrine tumors显示文摘AIM:To investigate the expression and potential prognostic role of vascular endothelial growth factor(VEGF) and endoglin in gastroenteropancreatic neuroendocrine tumors(GEP-NETs) . METHODS:Microvessel density(MVD) in GEP-NETs was evaluated using endoglin and CD31 immunohistochemistry.In addition,tissue levels of endoglin and VEGF were determined in homogenates by ELISA. RESULTS:Endoglin was highly expressed on tumor endothelial cells.CD31 MVD in GEP-NETs was significantly higher compared to endoglin MVD(P<0.01) .Two-tofour-fold higher tissue levels of endoglin and VEGF were seen in tumors compared to associated normal tissue. This increased endoglin tissue expression in tumors was significantly related to tumor size(P<0.01) ,presence of metastases(P=0.04) ,and a more advanced tumor stage(P=0.02) ,whereas expression of VEGF was not. CONCLUSION:We suggest that endoglin is a potential marker to indicate and predict metastases,which might be useful in the post-resection therapeutic approach of patients with GEP-NETs.Patricia Kuiper Lukas JAC Hawinkels Eveline SM de Jonge-Muller Izk Biemond Cornelis BHW Lamers Hein W Verspaget 2011World Journal of Gastroenterology2011,17,2:4
2Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett’s oesophagus显示文摘Florine Kastelein Katharina Biermann Ewout W Steyerberg Joanne Verheij Marit Kalisvaart Leendert H J Looijenga Hans A Stoop Laurens Walter Ernst J Kuipers Manon C W Spaander Marco J Bruno 2013Gut2013,,12:2
3Numerical calculation of wall-to-bed heat-transfer coefficients in gas-fluidized beds显示文摘Kuipers JA M Prins W Swaaij W PM van 1992AIChE Journal1992,38,7:1
4Discrete particle simulation of bubble and slug formation in a two di mensional gas-fluidised bed: A hard sphere approach 显示文摘Hoomans B P B Kuipers J A M Briels W J 1996Chemical Engineering Science1996,51,1:1
5Controlling competence in Bacillus subtilis: shared use of regulators显示文摘Hamoen L W Venema G Kuipers O P 2003Microbiology2003,149,:1
6Intraocular interleukin-17 and proinflammatory cytokines in HLA-A29-associated birdshot chorioretinopathy 显示文摘Kuiper J J Mutis T de Jager W de Groot-Mijnes JD Rothova A 2011Am J Ophthalmol2011,152,2:1
7Radiation exposure of mufti-row detector spiral tomography of the pulmonary arteries: comparison with digital subtraction pulmonary angiography 显示文摘Kuiper J W Geleijns J Matheijssen N A 2003Eur Radiol2003,13,7:1
8Chain length dependence of α-olefin readsorption in Fischer-Tropsch synthesis显示文摘Kuipers E W Vinkenburg I H Oosterbeek H J 1995Journal of Catalysis1995,152,3:1
9Expression of recombinant membrane -bound type liodothyronine deiodinase in yeast 显示文摘Kuiper G G J M Klootwijk W Visser T J 2005J Mol Endocrinol2005,34,:1
10Discrete particle simulation of bubble and slug formation in a two-dimensional gas-fluidized bed: A hard-sphere approach显示文摘Hoomans B P B Kuipers J A M Briels W J 1996Chemical Engineering Science1996,51,1:1
11Dynamic simulation of gas-liquid two-phase flow:Effect of column aspect ratio on the flow structure显示文摘Delnoij E Kuipers J A M Swaaij van W P M 1997Chemical Engineering Science1997,52,21:1
12Variable focal length microlenses显示文摘Kuiper S Hendriks B H W 2000Optics Communication2000,177,16:1
13Variable-focus liquid lens for miniature cameras显示文摘Kuiper S Hendriks B H W 2004Applied Physics Letters2004,85,:1
14Dynamic simulation of gas-liquid two-phase flow: Effect of column aspect ratio on the flow structure显示文摘DELNOIJ E KUIPERS J A M van SWAAIJ W P M 1997Chem Eng Sci1997,52,21:1
15Dynamic simulation of gas-liquid two-phase flow: effect of column aspect ratio on the flow structure 显示文摘Delnoij E Kuipers J A M van Swaaij W P M 1997Chem Eng Sci1997,52,2122:1
16Self-reference and the encoding of personal information 显示文摘Rogers T B Kuiper N A Kirker W S 1977J Pers Soc Psychol1977,35,:1
17Discrete particle simulation of bubble and slug formation in a twodimension gas-fluidised bed: a hard-sphere approach 显示文摘Hoomans B P B Kuipers J A M Briels W J 1996Chemical Engineer Science1996,51,1:1
18Discrete particle simulation of bubble and slug formation in a two-dimensional gas-fluidised bed: Ahard-sphere approach显示文摘Hoomans B P B Kuipers J A M Briels W 1996ChemicalEngineering Science1996,51,1:1
19Lactic acid bacteria : the bugs of the new millennium 显示文摘Koings W N Kok J Kuipers 0 P 2000Curr Opin Microbiol2000,3,3:1
20Ensemble correlation PIV applied to bubble plumes rising I a bubble column 显示文摘Delnoij E Westerweel J Deen N G Kuipers J A M Van Swaaij W P M 1999Chemical Engineering Science1999,54,:1
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