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1A randomized controlled clinical trial on the treatment of Thymosin-a1 versus interferon-α in patients with hepatitis B显示文摘INTRODUCTIONChronic hepatitis B virus (HBV) infection is a serious problem because of its world wide distribution and possible adverse sequelae ,such as cirrhosis and hepatocellular carcinoma .The World Health Organization estimates that HBV has infected mord than 350 million people worldwide ,and up to 20% of them will become chromic carricrs and will be at significant risk for cirrhosis and HCC .The ultimate goal of the therapy for chronic hepatitis B is to prevent progression to cirrhosis and to prevent development of HCC.Jing You Lin Zhuang Bao Zhang Tang Wei Bo Yang Su Ying Ding Wu Li Rong Xue Wu Hong Li Zhang Yan Mei Zhang Shao Ming Yan Lu Zhang ~1Department of Infectious Diseases,The First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan Province,China ~2Departrnent of Hepatology,Kunming Third Municipal People’s Hospital,Kunming 650041,Yunnan Province,China 2001World Journal of Gastroenterology2001,7,3:48
2Interannual variability of Antarctic Oscillation and its influence on East Asian climate during boreal winter and spring显示文摘The interannual variability of Antarctic Oscillation (AAO) and its influence on East Asian climate during both boreal winter and spring are addressed. The results show that the positive AAO anomaly decreases the cold activity over East Asia during both boreal winter and spring. AAO-related barotropic meridional teleconnection from Antarctic to Arctic is found through analysis of mean me- ridional circulations. This meridional teleconnection is remarkable over Eurasia during boreal winter and over the Pacific Ocean during boreal spring. The results also show that zonal mean zonal wind at high latitudes in Southern Hemisphere has well positive correlation with that of Eurasia during boreal winter and has negative correlation with Pacific North American teleconnection (PNA) during boreal spring, which again display the meridional teleconnection. Thus, local meridional teleconnection is a possible linkage for interaction of circulations at mid-high latitudes between both hemispheres.FAN Ke1,2,3 & WANG Huijun2 1. Nansen-Zhu International Research Center, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2. Department of Atmospheric Science, Yunnan University, Kunming 650091, China 3. Graduate University of the Chinese Academy of Sciences, Beijing 100049, China 2006Science China Earth Sciences2006,49,5:36
3Fuzzy interface treatment in Eulerian method显示文摘In this paper, we incorporate fuzzy mathematics approach into the Eulerian method to simulate three dimensional multi-material interfaces. In particular, we propose a fuzzy interface treatment for describing interfaces, designing transport plans, and computing transport quantities. Using a set of three-dimensional inviscid isothermal elastic-plastic hydrodynamic equations, we simulate shaped charge jet in different filled dynamite structures. Strain and stress have been under consideration in simulations. Numerical results demonstrate that the fuzzy interface treatment is correct and efficient for three-dimensional multi-material problems.NING Jianguo1 & CHEN Longwei1,2 1. National Key Laboratory of Protection and Control of Explosive Disaster, Beijing Institute of Technology, Beijing 100081, China 2. The Faculty of Land Resource Engineering, Kunming University of Science and Technology, Kunming 650093, China Correspondence should be addressed to Ning Jianguo 2004Science China(Technological Sciences)2004,47,5:40
4Oscillation of Solutions of Nonlinear Partial Differential Equations of Neutral TypeYu Yuanhong Liu Bin Liu Zhengrong Institute of Applied Mathematics, Academia Sinica, Beijing 100080, China Department of Mathematics, Hubei Normal College, Huangshi 435002. China Department of Mathematics, Yunnan University. Kunming 650091. China Institute of Applied Mathematics of Yunnan Province, Kunming 650091, China 1997Acta Mathematica Sinica,English Series1997,13,4:39
5S-wave velocity and Poisson's ratio structure of crust in Yunnan and its implication显示文摘Receiver function of body wave under the 23 stations in Yunnan was extracted from 3-component broadband digital recording of teleseismic event. Thus, the S-wave velocity structure and distribution characteristics of Poisson's ratio in crust of Yunnan are obtained by inversion.The results show that the crustal thickness is gradually thinned from north to south. The crustal thickness in Zhongdian of northwest reaches as many as 62.0 km and the one in Jinghong of further south end is only 30.2 km. What should be especially noted is that there exists a Moho upheaval running in NS in the Chuxiong region and a Moho concave is generally parallel to it in Dongchuan. In addition, there exists an obvious transversal inhomogeneity for the S-wave veIocity structure in upper mantle and crust in the Yunnan region. The low velocity layer exists not only in 10.0-15.0 km in upper crust in some regions, but also in 30.0-40.0 km in lower crust.Generally, the Poisson's ratio is on the high side, however it has a better corresponding relation to the crustal velocity structure. An obvious block distribution feature is still shown on such a high background of Poisson's ratio. It is discovered by synthetically analyzing the velocity structure and Poisson's ratio distribution that there are high Poisson's ratio and complicated crust-mantle velocity structure feature in the Sichuan-Yunnan Diamond Block with Xiaojiang fault to be the east boundary and Yulong Snow Mountain fault to be the west boundary besides the frequent seismicity. This feature differs obviously from that of surrounding areas, which would provide geophysical evidence to deeply study the eastwardly flowage of lithospheric substances in the Qinghai-Tibet Plateau.HU Jiafu, SU Youjin, ZHU Xiongguan & CHEN Yun Geophysical Department of Yunnan University, Kunming 650091, China Seismological Bureau of Yunnan Province, Kunming 650041, China Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100101, China 2005Science China Earth Sciences2005,48,2:30
6Geochemistry and mineralogy of the Late Permian coals from the Songzao Coalfield, Chongqing, southwestern China显示文摘Mineralogy and geochemistry of the four main workable coal seams (No.6, No.7, No.8, and No.11) of Late Permian age from the Songzao Coalfield, Chongqing, Southwest China, were examined using in- ductively coupled plasma-mass spectrometry (ICP-MS), X-ray fluorescence spectrometry (XRF), cold-vapor absorption spectrometry (CV-AAS), ion-selective electrode (ISE), scanning electron mi- croscopy equipped with an energy-dispersive X-ray spectrometer (SEM-EDX), and X-ray diffraction analysis (XRD). The results showed that the main workable No.8 Coal that accounts for about 60% of the total coal reserves in the Songzao Coalfield was not enriched in hazardous trace elements. The No.11 Coal has high concentrations of alkaline elements, Be (9.14 μg/g), Sc (12.9 μg/g), Ti (9508 μg/g), Mn (397 μg/g), Co (23.7 μg/g), Cu (108 μg/g), Zn (123 μg/g), Ga (32 μg/g), Zr (1304 μg/g), Nb (169 μg/g), Hf (32.7 μg/g), Ta (11.4 μg/g), W (24.8 μg/g), Hg (0.28 μg/g), Pb (28.1 μg/g), Th (24.1 μg/g), and rare earth elements (509.62 μg/g). The concentration of Nb and Ta in the No. 11 Coal is higher than the industrial grade, and their potential utilization should be further studied. Besides pyrite, quartz, calcite, and clay minerals, trace minerals including chalcopyrite, marcasite, siderite, albite, mixed-layer clay minerals of illite and smectite, monazite, apatite, anatase, chlorite, and gypsum were found in the No.11 Coal. It should be noted that alabandite of hydrothermal origin and anatase occurring as cement were identi- fied in coal. In addition, the clayey microbands derived from alkaline volcanic ashes were identified in the coal. The dominant compositions of these clayey microbands were mixed-layer clay minerals of illite and smectite, which were interlayered with organic bands. The modes of occurrence of alkaline volcanic ash bands indicate that the volcanic activities were characterized by the multiple eruptions, short time interval and small scale for each eruption during peat accumulation. The alkaline volcanic ashes were the dominant factors for the enrichment of alkaline elements, Nb, Ta, Zr, Hf, and rare earth elements, and the sulfide minerals are the main carriers of Ga, Cu, and Hg in the No. 11 Coal.DAI ShiFeng1,2, ZHOU YiPing3, REN DeYi1, WANG XiBo1, 2, LI Dan1, 2 & ZHAO Lei1, 2 1 State Key Laboratory of Coal Resources and Safe Mining (China University of Mining and Technology), Beijing 100083, China 2 Department of Resources and Earth Science, China University of Mining and Technology, Beijing 100083, China 3 Kunming Research Institute of Coal Science, Kunming 650041, China 2007Science China Earth Sciences2007,50,5:27
7North Pacific sea ice cover, a predictor for the Western North Pacific typhoon frequency?显示文摘The relationship between the sea ice cover in the North Pacific and the typhoon frequency has been studied in this paper. It follows that the index for the sea ice cover in the North Pacific (ISA) both in December-January-February (DJF) and in March-April-May (MAM) is negatively correlated with annual typhoon number over the western North Pacific (TNWNP) during 1965―2004, with correlation coeffi-cients of -0.42 and -0.49 respectively (above 99% significant level). Large sea ice cover in the North Pacific tends to decrease TNWNP. Positive ISA (MAM) is associated with the tropical circulation and SST anomalies in the North Pacific, which may lead to unfavorable dynamic and thermal conditions for typhoon genesis over WNP from June to October (JJASO). The variability of the atmospheric circula-tion over the North Pacific, associated with the ISA anomaly in MAM is connected to the tropical at-mospheric circulation variability in MAM via the teleconnection wave train. Besides, as the tropical circulation has strong seasonal persistency from the MAM to JJASO, thus, the ISA in MAM-related variability of the tropical atmospheric circulation as well as the SST can affect the typhoon activity over the western North Pacific.FAN Ke Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China Department of Atmospheric Science, Yun-nan University, Kunming 650091, China 2007Science China Earth Sciences2007,50,8:25
8Preliminary results of Thymosin-a1 versus interferon-α treatment in patients with HBeAg negative and serum HBV DNA positive chronic hepatitis B显示文摘INTRODUCTIONIn China ,the incidence and mortality of gastric cancer rank the second among all cancers. Recent development of cancer [1-20].The aim of this study was investigat the insight of apoptosis and bcl-2, p53 and C-myc protein expression in the development of gastric cancer .Lin Zhuang Jing You Bao Zhang Tang Su Ying Ding Kui Hua Yan Dan Peng Yan Mei Zhang Lu Zhang ~1Department of Hepatology,Kunming Third Municipal Peoples Hospital,Kunming 650041,Yunnan Province,China ~2Department of Infectious Diseases,The First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan Province,China 2001World Journal of Gastroenterology2001,7,3:22
9A 60-year journey of mycorrhizal research in China:Past,present and future directions显示文摘The significance of mycorrhizas(fungal roots in 90% of land plants) in plant nutrient acquisition and growth,element biogeo-chemical cycling and maintaining of terrestrial ecosystem structures has been globally established for more than 120 years.Great progress in mycorrhizal research in the past 60 years(1950-2009,1981-2009 in particular) has also been made across China,particularly in the mainland,Hong Kong and Taiwan.For instance,a total of 20 new and ~120 records of arbuscular mycorrhizal(AM) fungal species,30 new and ~800 records of ectomycorrhizal(EM) fungal species,a dozen of new and ~100 records of orchid mycorrhizal(OM) fungal species have been isolated by morphological observation and/or molecular identification in China since the 1950s.Great accomplishment has also been made in the following area,including fungal species richness and genetic structure,relationships between species composition and plant taxa,effects of mycorrhizal fungi on plant nutrient uptake and growth,resistances to pathogens and interactions with other soil microorganisms,potential of mycorrhizal fungi in phytoremediation and/or land reclamation,alterations of enzymatic activities in mycorrhizal plants,and elevated CO2 and O3 on root colonization and species diversity.Unfortunately,the international community cannot easily appreciate almost all Chinese mycorrhizal studies since the vast majority of them have been published in Chinese and/or in China-based journals.The aim of this review is to make a comprehensive exposure of the past and present China's major mycorrhizal research to the whole world,and then to suggest potential directions for the enhancement of future mycorrhizal research within and/or between the Chinese and international mycorrhizal community.HE XinHua1,2,3*,DUAN YingHua2,CHEN YingLong4 & XU MingGang2 1School of Life Sciences,Yunnan Normal University,Kunming 650092,China 2Key Laboratory of Crop Nutrition and Fertilization,Ministry of Agriculture of China,Institute of Agricultural Resources and Regional Planning,Chinese Academy of Agricultural Sciences,Beijing 100081,China 3Centre for Ecosystem Management,School of Natural Resources,Edith Cowan University,Joondalup,WA 6027 State Centre of Excellence for Ecohydrology,School of Plant Biology,University of Western Australia,Crawley,WA 6009,Australia 4School of Earth and Environment,University of Western Australia,Crawley,WA 6009,Australia 2010Science China(Life Sciences)2010,53,12:23
10Mineralization episode of porphyry copper deposits in the Jinshajiang-Red River mineralization belt: Re-Os dating显示文摘Re-Os isotopic dating for the molybdenites from the porphyry copper deposits of the Jinshajiang-Red River mineralization belt in Yunnan Province yields isochron ages of 33.9±1.1 Ma for the Machangqing deposit and 34.4±0.5 Ma for the Tongchang deposit. This result shows that both the Machangqing and the Tongchang porphyry Cu-Mo deposits from two different ore-fields formed simultaneously. This new data and the published Re-Os model ages of molybdenite (35.4 Ma, 35.9 Ma, 36.2 Ma) of the Yulong porphyry copper deposit in Tibet, which is located in the same Jinshajiang-Red River mineralization belt as the Machangqing deposit and the Tongchang deposit, suggest that these three Cenozoic porphyry copper deposits in the Jinshajiang-Red River mineralization belt were contemporary for their mineralization episode. That is to say, even their present locality is far away and nearly iso-distantly distributed, these three porphyry Cu(Mo) deposits belong to the same mineralization episode at the end of Eocene.WANG Denghong, QU Wenjun, LI Zhiwei, YIN Hanlong4 & CHEN Yuchuan Institute of Mineral Resources, Chinese Academy of Geological Sciences, Beijing 100037, China National Center of Rock and Mineral Analysis, Chinese Academy of Geological Sciences, Beijing 100037, China Resource Assessment Center of Yunnan, Kunming 650011, China Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100101, China Chinese Academy of Geological Sciences, Beijing 100037, China 2005Science China Earth Sciences2005,48,2:21
11Two Novel Antifungal Saponins from Tibetan Herbal Medicine Clematis tangutica显示文摘Antifungal assay-guided isolation of the ethanol extract of the aerial parts of Clematis tangutica yielded two novel triterpene saponins. Their structures were determined to be 3-O-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (1) and 3-O-b-D- glucopyranosyl(14)-a-L-arabinopyranosyl hederagenin 28-O-a-L-rhamnopyranosyl ester (2) on the basis of spectral data and chemical reactions.Zhi Zhi DU, Na ZHU, Yue Mao SHEN* Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204 2003Chinese Chemical Letters2003,14,7:20
12The formation mechanism of high-quality dolomite reservoir in the deep of Puguang Gas Field显示文摘The discovery of Puguang Gas Field provides the exploration of China deep marine carbonate rock with important references.In Puguang Gas Field,the dolomite reservoirs discovered in the deep are the best in the present of China,which present big thickness and wide-range distribution,and develop abundant secondary porosity.The researches show that Puguang Gas Field bears the characteristics of early gas-filling time,deep burial,high matured organic matter and long-term interaction of hydrocarbon(oil and gas)-water-rock(carbonate reservoir).The developments of secondary pores in this area are affected by multiple diagenesis and their formation mechanisms are complicated.Through the research on depositional environment,sedimentary facies and reservoir porosity characters of Changxing and Feixianguan Formations,it is thought that high-quality dolomite reservoirs of Puguang Gas Field form on the favorable sedimentary facies belts,which are the integrate result affected by several factors including superficial corrosion,burial corrosion,overpressure and tectonic movement,among which burial corrosion of TSR to reservoir and overpressure formed by thermal evolution of organic matter have great effect on the formation of secondary porosity of Changxing and Feixianguan Formations.MA YongSheng 1 ,GUO TongLou 1 ,ZHAO XueFeng 2 &CAI XunYu 1 1 Southern Exploration&Production Company,Sinopec,Kunming 650200,China 2 China University of Mining and Technology,Beijing 100083,China 2008Science China Earth Sciences2008,51,S1:19
13Hepatitis C virus infections and genotypes in China显示文摘Objective: To define the conditions of hepatitis C vi-rus (HCV) infections, and geographic and demo-graphic distributions of genotypes in China.Methods: HCV infected patients were selected fromindividuals with different patterns of liver diseasesand high risk populations in different parts of China.Genotypes of HCV in some isolates were further ana-lyzed, based on the data from our laboratory studiesand some carefully selected published literatures.Results: The anti-HCV positive rates were 9.7% inpatients with acute hepatitis, 13.3% in patients withchronic hepatitis, 18.3% in patients with hepatocel-lular carcinoma, 33.0% in patients with liver cirrho-sis, and 43.2% in patients with posttransfusionalhepatitis (average, 16.2% in patients with liver di-seases). The anti-HCV positive rates in the high riskpopulations were 36.4% in leukemic patients,43.0% in hemodialysis patients, 12.7% in blood do-nors, 64.1% in drug abusers, 13.1% in prostitutes,and 2.57% in naturally healthy people. At least 4clades (clades 1, 2, 3 and 6) of HCV were found inChina with different geographic and demographicdistributions. Genotype 1b was the most widely dis-tributed genotype, and genotype 3 was mainly foundin Yunnan Province, Southwest China.Conclusion: China has a high incidence of HCV in-fection. Our results will provide a strategic basis fordiagnosis, treatment and possibly prophylaxis of he-patitis C virus diseases.Yuan-Ding Chen Ming-Ying Liu Wen-Lin Yu Jia-Qi Li Mei Peng Qing Dai Xiao Liu Zhen-Quan Zhou From the Central Laboratory, Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, China Kunming Hospital for Infectious Diseases, Kunming 650041, China 2002Hepatobiliary & Pancreatic Diseases International2002,1,2:18
14STUDY ON THE SHOCK WAVE CRYSTALLIZATION OF AMORPHOUS ALLOYS BY DSC显示文摘Shock wave and annealing crystallization of amorphous alloys FeSiB, FeMoSiB andFeCuNbSiB were studied by isothermal and non-isothermal DSC technique. It wasfound that the shock wave crystallization is very perfect, the fraction crystallized isvery close to 100%, though the period of crystallization is very short, only about10-4-10-6 s. Their produced phases differ from the parent phase in structure andcomposition. The high velocity of the transformation is very difficult to explain by thediffusion theory of solid state phase transition.H. Y. Zhao, H. Wang, Q.J. Liu, J.D. Kan and Z.Q. LiuDepartment of Materials Science and Engineering, Yunnan University, Kunming 650091, China 2002Acta Metallurgica Sinica(English Letters)2002,15,5:18
15CATHODIC PROCESS AND WEAR RESISTANCE OF ELECTRO-DEPOSITED RE-Ni-W-P-SiC COMPOSITE COATING显示文摘Cathodic deposition current density of the composite coatings increases when SiC par-ticles and rare earth (RE) were added in the bath, which is profitable for Ni- W-P alloyto deposit in the cathod, forming Ni-W-P-SiC and RE-Ni-W-P-SiC composite coat-ings. On the contrary, the addition of PTFE in the bath decreases cathodic depositioncurrent density of the coatings. The current density increases a little when the amountof RE is 7-9g/l; however, the current density increases greatly when the amount ofRE is increased to 11-13g/l. But if the amount of RE is raised further, the currentdensity decreases. Hardness and wear resistance of RE-Ni-W-P-SiC composite coat-ing have been studied, and the results show that the hardness and wear resistance ofRE-Ni-W-P-SiC composite coating increase with increasing heat treatment tempera-ture, which reach peak values at 400℃; while the hardness and wear resistance of thecoating decrease with the rise of heat treated temperature continuously.Z.C.Guo,X.Y.Zhu,R.D.Xu and X.W.YangFaculty of Material and Metallurgy Engineering, Kunming University of Science and Technology, Kunming650093, ChinaManuscript received 26 December 2001 in revised form 23 April 2002 2002Acta Metallurgica Sinica(English Letters)2002,15,4:16
16PROPERTIES OF ELECTRODEPOSITED AMORPHOUS Ni-W-P-SiC COMPOSITE COATINGS显示文摘PROPERTIESOFELECTRODEPOSITEDAMORPHOUSNi-W-P-SiCCOMPOSITECOATINGSGUOZhongcheng;LIUHongkang;WANGZhiyin;WANGMin(DepartmentofMeta...GUO Zhongcheng LIU Hongkang WANG Zhiyin WANG Min(Department of Metallurgy,Kunming institute of Technology,Kunming 650093,China) 1996Acta Metallurgica Sinica(English Letters)1996,9,1:16
17INFLUENCE OF NaCl DEPOSITION ON ATMOSPHERIC CORROSION OF A3 STEEL IN THE PRESENCE OF SO_2显示文摘The regularities of atmospheric corrosion of A3 steel deposited with different amountof NaCl exposed to the air containing 1ppm SO2 at 80% RH and 25℃ were studied inlaboratory. NaCl can accelerate the corrosion of A3 steel obviously under such con-dition. The relationship between the weight loss of A3 steel and the amount of NaCldeposition can be well described by using a quadratic function. Fourier transform in-frared spectroscopy (FTIR), X-ray diffraction (XRD), Scanning electron microscopyand electron dispersion X-ray analysis (SEM/EDAX) were used to characterize thecorrosion products. In the absence of NaCl, FeSO4 xH2O is the dominant corro-sion products, while Fe3O4, FeSO4@ H2O, β-FeOOH and γ-FeOOH dominate in thepresence of NaCl.Q. Qu, C.W. Yan, L. Zhang , Y. Wan and C.N. CaoState Key Laboratory for Corrosion and Protection, Institute of Metal Research, The Chinese Academy of Sciences, Shenyang 110016, ChinaDepartment of Chemistry, Yunnan University, Kunming 650091, ChinaSchool of Chemical Science and Engineering, Liaoning University, Shenyang 110036, China 2002Acta Metallurgica Sinica(English Letters)2002,15,5:13
18微波场中甲烷部分氧化制合成气 Ⅱ.Co/ZrO_2催化剂在微波场中的升温行为及催化活性显示文摘近年来,甲烷部分氧化制合成气(POM)的研究一直十分活跃[1,2].前文报道了用于甲烷部分氧化制合成气的镍基催化剂(Ni/La2O3)在微波场中的升温行为和催化活性[3],发现在达到相同的CH4转化率时,微波活化方式下的催化剂床层温度比常规加热低得多...Bi Xianjun 1, Xie Xiaoguang 2, Duan Aihong 1, Wang Zhen 3, Hong Pinjie 3, Dai Shushan 3 (1 Department of Chemistry, Yunnan Normal University, Kunming 650092 2 Modern Biological Center, Yunnan University, Kunming 650091 3 Department of Chemi 1998催化学报1998,19,5:13
19Phase behavior of TXs/toluene/water microemulsion systems for solubilization absorption of toluene显示文摘Triton Xs(TXs) surfactants/cosurfactant/water/oil(toluene) microemulsion systems for enhancing toluene solubilization were proposed and its potential was investigated for toluene removal from gas stream.The results indicated that TX-100 was superior to other TXs surfactants in removing toluene without cosurfactant.The efficiency of cosurfactants for improving toluene solubilization capacity follows the order:amine>alcohol>acid.According to the factor analysis,the linear cosurfactants are better than the branched ones.The effects of hydrophile-lipophile balance(HLB),salt(NaCl) concentration and temperature on the formation of microemulsion system were also discussed.The results suggested that the optimum value of HLB was 15,the effect of NaCl concentration on the system was inconspicuous and the lower temperature enhanced the solubilization capacity.Nonionic surfactant-based microemulsions had a significant absorption enhancement for toluene,indicated by as much as 82.72% of toluene in phase composition diagram,which will have a great prospect in air pollution treatment.Lian Liu,Senlin Tian ,Ping Ning Faculty of Environmental Science and Engineering,Kunming University of Science and Technology,Kunming 650093,China 2010Journal of Environmental Sciences2010,22,2:13
20Application of laparoscopic cholecystectomy in patients with cirrhotic portal hypertension显示文摘BACKGROUND: Laparoscopic cholecystectomy (LC) has been widely adopted in treating benign gallbladder disea- ses. Cirrhosis and cirrhotic portal hypertension (CPH) are contraindicated for LC in its early period. In recent years, several studies have reported liberal use of LC in patients with cirrhosis. But its benefits and successful use in patients with CPH are less documented. This study was designed to evaluate the feasibility, safety and technical characteristics of LC in CPH patients. METHODS: In 38 patients with symptomatic gallbladder disease and CPH, 19 belonged to Child A class, 15 Child B class and 4 Child C class. Perioperative data of these pa- tients were collected and analyzed. RESULTS: LC was successfully performed in 36 patients, and 2 patients (5.3%) were converted to open cholecystec- tomy (OC) for difficulty in management of bleeding under laparoscopy and dense adhesion of Calot’ s triangle. The sur- gical time was 62.6±15.2 minutes. The estimated amount of intraoperative hemorrhage was 75.5±15.5 ml. No blood transfusion was necessary. The time to resume diet was 18.3 ±6.5 hours. Seven postoperative complications in 5 patients (13.2%) included port-site infection (1 patient), respiratory infection (2), upper digestive tract bleeding (1), slight hepatic encephalopathy (1) and increased ascites (2). All patients were cured and discharged from the hospital within 5.6±2.4 days after LC. CONCLUSIONS: Despite LC is difficult for CPH patients, it is feasible and relatively safe. To make LC successful in patients with CPH, it is necessary for surgeons to acquaint with the technical characteristics of LC and emphasize me- ticulous perioperative management.Wu Ji, Ling-Tang Li, Xun-Ru Chen and Jie-Shou Li Nanjing, ChinaResearch Institute of General Surgery, Nanjing Ge- neral Hospital of Nanjing PLA Command, Nanjing 210002, China and Department of Hepatobiliary Surgery, Kunming General Hospital of Chengdu PLA Command, Kunming 650032, China 2004Hepatobiliary & Pancreatic Diseases International2004,3,2:13
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