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| 1 | Review article:remission rates achievable by current therapies for inflammatory bowel disease显示文摘 | Peyrin-Biroulet L Lémann M | 2011 | Aliment Pharmacol Ther2011，33，： | 1 |
| 2 | Role of endoscopy in predicting the disease course in inflammatory bowel disease显示文摘Endoscopy provides a direct evaluation of mucosal lesions in inflammatory bowel disease(IBD),permitting the description of elementary lesions,their surface extent and severity.The severity of mucosal lesions directly reflects disease activity and may help to identify an aggressive behavior of the disease.Several studies have recently pointed out the potential role of endoscopy in the prediction of IBD outcome.Indeed,severe endoscopic lesions in Crohn's disease(CD) patients,defined by deep and extensive ulcerations on at least one part of the colon,are associated with an increased risk of penetrating complication and surgery.Severe endoscopic lesions during severe attacks of ulcerative colitis(UC) are associated with an increased risk of colectomy in the short and long term.Severity of postoperative recurrence in CD may help to predict the risk of clinical relapse and need for further surgery.Achievement of mucosal healing,which can be obtained by administration of several types of drugs,is associated with a better outcome,less surgery and hospitalization.This review focuses on the assessment of endoscopic severity in CD and UC and on the impact of endoscopic severity on disease outcome.More specifically,we discuss how endoscopy can be used at different stages of IBD to predict the disease course and/or to adapt treatment strategies. | Matthieu Allez Marc Lémann | 2010 | World Journal of Gastroenterology2010，16，21： | 10 |
| 3 | Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease:a randomised,double blind,placebo controlled GETAID trial显示文摘 | Marteau P Lémann M Seksik P | 2006 | Gut2006，55，： | 1 |
| 4 | Decreases in serum levels of S100A8/9(calprotecrin)correlate with improvements in total swollen joint count in patients with recent-onset rheumatoid arthritis显示文摘 | Andrés Cerezo L Mann H Pecha O | | 0，，04： | 1 |
| 5 | European evidence based consensus on the diagnosis and management of Crohn's disease:current management显示文摘 | Travis SPL Stange E F Lémann M | 2006 | Gut2006，55，： | 1 |
| 6 | Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol显示文摘 | Hébuterne X Lémann M Bouhnik Y | | 0，，： | 1 |
| 7 | Infliximab plus azathioprine for steroid-dependent Crohn's disease patients:a randomized placebo-controlled trial显示文摘 | Lémann M Mary JY Duclos B | 2006 | Gastroenterology2006，130，4： | 1 |
| 8 | 长期应用硫唑嘌呤的克罗恩病患者的随机、双盲、对照停药试验 | Lémann M. Mary J.-Y. Colombel J.-F. 王铮 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，10： | 0 |
| 9 | A Randomized, Double-Blind, Controlled Withdrawal Trial in Crohn’s Disease Patients in Long-term Remission on Azathioprine显示文摘 | Marc Lémann Jean-Yves Mary Jean-Frédéric Colombel Bernard Duclos Jean-Claude Soule Eric Lerebours Robert Modigliani Yoram Bouhnik | 2005 | Gastroenterology2005，，7： | 2 |
| 10 | A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn’s disease显示文摘 | Jean-Frédéric Colombel Marc Lémann Michel Cassagnou Yoram Bouhnik Bernard Duclos Jean-Louis Dupas Bertrand Notteghem Jean-Yves Mary | 1999 | The American Journal of Gastroenterology1999，，： | 2 |
| 11 | Infiltration graisseuse diffuse et primitive du pancréas : une cause rare de stéatorrhée显示文摘 | Alain Aubert Jean-Marc Gornet Pascal Hammel Philippe Lévy Dermot O’toole Philippe Ruszniewski Robert Modigliani Marc Lémann | 2007 | Gastroenterologie Clinique et Biologique2007，，3： | 1 |
| 12 | A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn’s disease显示文摘 | Jean-Frédéric Colombel Marc Lémann Michel Cassagnou Yoram Bouhnik Bernard Duclos Jean-Louis Dupas Bertrand Notteghem Jean-Yves Mary | 1999 | The American Journal of Gastroenterology1999，，3： | 1 |
| 13 | 英夫利昔单抗治疗克罗恩病的有效性:一项随访15个月的多中心回顾性研究结果显示文摘Objectives-To evaluate prescription practices and response to infliximab treatment for Crohn’s disease(CD).Patients and methods-The files of CD patients treated with at least one infusion of infliximab treated in gastroenterology units belonging to university teaching hospitals of the Parisian hospitals group(Assistance Publique-Hpitaux de Paris(AP-HP))during the year 2000 were analyzed retrospectively.Results-One hundred and thirty-seven patients(36.0 ±12.7 years,92 females)from 12 centers were studied.Indication for treatment was fistulae or perianal disease in 39%of patients,active Crohn’s disease in 45and mixed conditions in 16%.Mean follow-up was 15.2 ±7.2 months.The overall response rate was 85%.No predictive factor of sustained remission could be identified.The mean time to relapse was to 3.9 ±3.1 months.Thirty-eight patients were on maintenance therapy at the end of the follow-up;37%exhibiting progressive lost of response to treatment.Immunosuppressive therapy was added to infliximab in 78%of cases but response to infliximab was not modified by addition of immunosuppressive drugs.Adverse events,most frequently minor,were noted in 23%of the patients.Conclusion-This retrospective study confirms the efficacy and safety of infliximab in CD. | Poupardin C. Lémann M. Gendre J.-P. B .Coffin 张诗峰(译) 李文彬(校) | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，9： | 1 |
| 14 | <ce:link locator='fx1'/> A Review of Activity Indices and Efficacy End Points for Clinical Trials of Medical Therapy in Adults With Ulcerative Colitis显示文摘 | Geert D’Haens William J. Sandborn Brian G. Feagan Karel Geboes Stephen B. Hanauer E. Jan Irvine Marc Lémann Philippe Marteau Paul Rutgeerts Jurgen Sch?lmerich Lloyd R. Sutherland | 2007 | Gastroenterology2007，，2： | 2 |
| 15 | European evidence-based Consensus on the management of ulcerative colitis: Current management显示文摘 | S.P.L. Travis E.F. Stange M. Lémann T. ?resland W.A. Bemelman Y. Chowers J.F. Colombel G. D'Haens S. Ghosh P. Marteau W. Kruis N.J.McC. Mortensen F. Penninckx M. Gassull | 2008 | Journal of Crohn’s and Colitis2008，，1： | 2 |
| 16 | <ce:link locator='fx1'/> A Review of Activity Indices and Efficacy End Points for Clinical Trials of Medical Therapy in Adults With Ulcerative Colitis显示文摘 | Geert D'Haens William J. Sandborn Brian G. Feagan Karel Geboes Stephen B. Hanauer E. Jan Irvine Marc Lémann Philippe Marteau Paul Rutgeerts Jurgen Sch?lmerich Lloyd R. Sutherland | 2007 | Gastroenterology2007，，2： | 2 |
| 17 | Intravenous cyclosporine in attacks of ulcerative colitis显示文摘 | Dr. Franck Carbonnel MD Arnaud Boruchowicz MD Bernard Duclos MD Jean Claude Soulé MD Eric Lerebours MD Marc Lémann MD Jean Bela?che MD Jean Frédéric Colombel MD Jacques Cosnes MD Jean Pierre Gendre MD | 1996 | Digestive Diseases and Sciences1996，，12： | 1 |
| 18 | Colonoscopy of acute colitis显示文摘 | Franck Carbonnel MD Anne Lavergne MD Marc Lémann MD Alain Bitoun MD Patrice Valleur MD Pierre Hautefeuille MD Annie Galian MD Robert Modigliani MD Dr. Jean-Claude Rambaud MD | 1994 | Digestive Diseases and Sciences1994，，7： | 1 |
| 19 | <ce:link locator='fx1'/> A Review of Activity Indices and Efficacy End Points for Clinical Trials of Medical Therapy in Adults With Ulcerative Colitis显示文摘 | Geert D’Haens William J. Sandborn Brian G. Feagan Karel Geboes Stephen B. Hanauer E. Jan Irvine Marc Lémann Philippe Marteau Paul Rutgeerts Jurgen Sch?lmerich Lloyd R. Sutherland | 2007 | Gastroenterology2007，，2： | 1 |
| 20 | Colonoscopy of acute colitis显示文摘 | Franck Carbonnel MD Anne Lavergne MD Marc Lémann MD Alain Bitoun MD Patrice Valleur MD Pierre Hautefeuille MD Annie Galian MD Robert Modigliani MD Dr. Jean-Claude Rambaud MD | 1994 | Digestive Diseases and Sciences1994，，7： | 1 |
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