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| 1 | Green tea extract:A potential cause of acute liver failure显示文摘The use of herbal products has increased significantly in recent years.Because these products are not subject to regulation by the Food and Drug Administration and are often used without supervision by a healthcare provider,the indication for and consumption of these supplements is quite variable.Moreover,their use is generally regarded as safe and natural by the lay-public.Unfortunately,there has been an increase in the number of reported adverse events occurring with the use of herbal products.We present a case of acute impending liver failure in an adolescent male using a weightloss product containing green tea extract.Our case adds to the growing concern surrounding the ingestion of green tea extract and serves to heighten healthcare provider awareness of a potential green tea extract hepatotoxicity.Despite the generally touted benefits of green tea as a whole,clinical concern regarding its use is emerging and has been linked to its concentration in multiple herbal supplements.Interestingly,the suspected harmful compounds are those previously proposed to be advantageous for weight-loss,cancer remedy,and anti-inflammatory purposes.Yet,we emphasize the need to be aware of not just green tea extract,but the importance of monitoring patient use of all dietary supplements and herbal products. | Shreena S Patel Stacey Beer Debra L Kearney Garrett Phillips Beth A Carter | 2013 | World Journal of Gastroenterology2013，19，31： | 3 |
| 2 | Prognostically relevant gene signatures of high-grade serous ovarian carcinoma显示文摘 | Verhaak Roel G W Tamayo Pablo Yang Ji-Yeon Hubbard Diana Zhang Hailei Creighton Chad J Fereday Sian Lawrence Michael Carter Scott L Mermel Craig H Kostic Aleksandar D Etemadmoghadam Dariush Saksena Gordon Cibulskis Kristian Duraisamy Sekhar | 2013 | Journal of Clinical Investigation2013，，1： | 2 |
| 3 | Folate and vitamin B12 in idiopathic male infertility显示文摘尽管 methylenetetrahydrofolate reductase,叶酸的酶基因,与自发的男不孕被联系了,很少研究检验了另外的叶酸相关的代谢物和基因。我们调查了自发的男不孕是否与变体被联系在叶酸,维生素 B 12(B12 ) 和全部的 homocysteine (tHcy ) 联系了基因并且在血测量了这些代谢物。我们进行了与自发的不孕和在生育力中心和胎儿的照顾中心招募的 184 肥沃的男控制包括了 153 个人的盒子控制研究,大学医院, Malmö并且 Lund,瑞典。浆液叶酸的、红房间叶酸(RCF ) ,浆液 B12,血浆 tHcy 和精液质量被测量。题目是为在与 folate/B12/homocysteine 新陈代谢有关的 12 基因的 20 普通变体的 genotyped。代谢物集中和遗传型分布为 covariates 与调整用线性、逻辑的回归在案例和控制之间被作比较。phosphatidylethanolamine N-methyltransferase (PEMT ) M175V 和 TCblR rs173665 多型性显著地与不孕被联系(P=0.01 和 P=0.009,分别地) ,然而并非与精液质量。在补充的非用户之中,有的不肥沃的人降低浆液叶酸的集中比肥沃的人(12.89 对 14.73 nmol l −1 ;P=0.02 ) ,但是在 RCF, B12 或 tHcy 没有重要差别。叶酸, B12 和 tHcy 集中没与任何精液参数被相关。这研究几乎不提供小支持为低叶酸或在自发的男不孕的致病的 B12 地位。尽管另外的数据被需要证实这些起始的调查结果,我们的结果建议那 PEMT 和 TCblR,基因在胆碱和 B12 新陈代谢包含了,在自发的男不孕应得进一步的调查。 | Laurel E Murphy James L Mills Anne M Molloy Cong Qian Tonia C Carter Helena Strevens Dag Wide-Swensson Aleksander Giwercman Richard J Levine | 2011 | Asian Journal of Andrology2011，13，6： | 2 |
| 4 | Imaging Fourier Transform Spectrometer显示文摘 | Bennett C L Carter M Fields D | 1993 | SPIE1993，1937，： | 1 |
| 5 | Genetic base of 651Chinese soybean eultivars released during 1923 to 1995 显示文摘 | Cui Z L Thomas E Carter J Burton J W | 2000 | Crop Science2000，40，： | 1 |
| 6 | PD-1 : PD-L inhibitory pathway affects both CD4^+ and CD8^+ T cells and is overcomed by IL-2显示文摘 | Carter L Fouser LA Jussif J | 2002 | Eur J Immunol2002，32，： | 1 |
| 7 | Evidence that physiLologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase acivity显示文摘 | Carlson S E Mitchell A D Carter M L | 1980 | Biochem Biophys Acta1980，633，： | 1 |
| 8 | Development of ozone reactivity scales for volatile organic compounds 显示文摘 | Carter W P L | 1994 | J Air Waste Manag Assoc1994，44，7： | 1 |
| 9 | Ethylene glycol monoe- thyl ether for determining surface area of silicate minerals 显示文摘 | Carter D L Heilman M D Gonzalez C L | 1965 | Soil Science1965，100，6： | 1 |
| 10 | Freezing effects on aggregate stability affected by texture, mineralogy, and organic matter显示文摘 | Lehrsch G A Sojka R E Carter D L | 1991 | Soil Science Society of America Journal1991，55，： | 1 |
| 11 | Development of subscales from the symptom/Problem and effect of kidney disease scales of kidney disease quality of life instrument显示文摘 | Rao S Carter W B Mapes D L | 2000 | Clin Ther2000，22，： | 1 |
| 12 | Geodetic im- aging with airborne LiDAR: The Earth's surface revealed 显示文摘 | Glennie C L Carter W E Shrestha R L | 2013 | Reports on Progress in Physics2013，76，8： | 1 |
| 13 | Coconut oil extraction by a new enzymatic process显示文摘 | McGlone O C Canales A L M Carter J V | 1986 | Journal of Food Science1986，51，3： | 1 |
| 14 | Transgenic pollen harms monarch larvae显示文摘 | Losey J E Royor L S Carter M E | 1999 | Nature1999，399，： | 1 |
| 15 | A mutation in COL9A1 causes multiple epi- physeal dysplasia: further evidence for locus heterogeneity 显示文摘 | Czarny-Ratajczak M Lohiniva J Rogala P Kozlowski K Perala M Carter L | 2001 | Am J Hum Genet2001，69，5： | 1 |
| 16 | Development of ozone reactivity scales for volatileorganic compounds显示文摘 | Carter W P L | 1994 | Journal of the Air and WasteManagement Association1994，44，7： | 1 |
| 17 | Physiological substrates of mammalian monogamy: the prairie vole model 显示文摘 | Carter C S DeVries A C Getz L L | 1995 | Neurosci Biobehav Rev1995，19，2： | 1 |
| 18 | Storage of sediment-associated nutrients and contaminants in river channel and floodplain systems显示文摘 | Walling D E Owens P N Carter J Leeks G J L Lewis S Meharg A A and Wright J | 2003 | Applied Geochemistry2003，18，： | 1 |
| 19 | Effects of adding fiber sources to reduced-crude protein,amino acid-supplemented diets on nitrogen excretion,growth performance,and carcass traits of finishing pigs1,2显示文摘 | Shriver J A Carter S D Sutton A L | 2003 | Journal of Animal Science2003，81，： | 1 |
| 20 | BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis 显示文摘 | Wilhelm SM Carter C Tang L | 2004 | Cancer Res2004，64，19： | 1 |
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