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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Computerized physician order entry‐based system to prevent HBV reactivation in patients treated with biologic agents: The PRESCRIB project显示文摘 | Blanca Sampedro Cándido Hernández‐López José Ramón Ferrandiz Aitziber Illaro Emilio Fábrega Antonio Cuadrado Paula Iruzubieta Susana Menéndez Joaquín Cabezas Javier Crespo | 2014 | Hepatology2014，，1： | 2 |
| 3 | Factors that impact health-related quality of life in adults with celiac disease:A multicenter study显示文摘AIM: To evaluate the factors involved in the impairment of health-related quality of life (HRQOL) in patients with celiac disease.METHODS: A multicenter, cross-sectional prospective study was performed in patients with celiac disease who completed two HRQOL questionnaires: the gastrointestinal quality of life index (GIQLI) and the EuroQol-5D (EQ).RESULTS: Three hundred and forty patients (163 controlled with a gluten-free diet, and 177 newly diagnosed with a normal diet) were included. The GIQLI score was significantly better in patients on a gluten-free diet (GFD) than in non-treated patients on their usual diet, both in terms of the overall score (3.3 vs 2.7, respectively; P < 0.001), as well as on the individual questionnaire dimensions. Both the preference value of the EQ as the visual analogue scale were significantly better in treated than in non-treated patients (0.93 vs 0.72 P < 0.001 and 80 vs 70 P < 0.001, respectively). Variables significantly associated with a worse HRQOL score were female gender, failure to adhere to a GFD, and symptomatic status.CONCLUSION: In untreated celiac disease, the most important factors that influence patient perception of health are the presence of symptoms and a normal diet. HRQOL improves to levels similar to those described in the general population in celiac disease patients well controlled with a GFD. | F Casellas L Rodrigo J López Vivancos S Riestra C Pantiga JS Baudet F Junquera V Puig Diví C Abadia M Papo J Gelabert JR Malagelada | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 4 | Volatile compounds,quality parameters and consumer acceptance of ‘Pink Lady' apples stored in different conditions显示文摘 | López M L Villatoro C Fuentes T | 2007 | Postharvest Biology and Technology2007，，43： | 1 |
| 5 | Locating some types of random errors in Digital Terrain Models显示文摘 | LóPEZ C | 1997 | International Journal of Geographic Information Science1997，11，： | 1 |
| 6 | Solving an assignment-selection problem with verbal information and using genetic algorithms显示文摘 | Herrera F López E Mendana C | 1999 | Europearn Journal of Operational Research1999，119，2： | 1 |
| 7 | Influence of sodium fumarate addition on rumen fermentation in vitro显示文摘 | López S Valdes C Newbold C J | 1999 | British Journal of Nutrition1999，81，： | 1 |
| 8 | On the improving of elevation accuracy of Digital Elevation Models:a comparison of some error detecting procedures显示文摘 | LóPEZ C | 2000 | Transactions in GIS2000，，4： | 1 |
| 9 | Changes in transcrption within the CA1 field of the hippocampus areassociated with age-related spatial learning impairments显示文摘 | Burger C López M C Feller J A | 2007 | Neurobiol Learn Mem2007，87，1： | 1 |
| 10 | Real-time deformable models for surgery simulation:a survey显示文摘 | Meier U López O Monserrat C | 2005 | Comput Methods Programs Biomed2005，77，3： | 1 |
| 11 | An experiment on elevation accuracy improvement of photogrammetrically derived DEM显示文摘 | LóPEZ C | 2002 | International Journal of Geographical Information Science2002，，4： | 1 |
| 12 | Role of caveolins in body weight and insulin resistance regulation显示文摘 | Frühbeck G López M Diéguez C | 2007 | Trends Endocrinol Metab2007，18，5： | 1 |
| 13 | Laparoscopic surgery in the elderly patient显示文摘 | Bàllesta López C Cid JA Poves I | 2003 | Surg Endosc2003，17，2： | 1 |
| 14 | Automatic construction of optimal static sequential portfolios for AI planning and beyond显示文摘 | Núez S Borrajo D López C L | 2015 | Artificial Intelligence2015，226，9： | 1 |
| 15 | Pregnancy and Kidney Transplantation,Triple Hazard?Current Concepts and Algorithm for Approach of Preconception and Perinatal Care of the Patient With Kidney Transplantation显示文摘 | L Pez L F Mart Nez C J Casta Eda D A | 2014 | Transplantation Proceedings2014，46，9： | 1 |
| 16 | A simple and costeffective approach for microsatellite isolation in non-model plant species using small-scale 454 pyrosequencing显示文摘 | TAKAYAMA K LPEZ P S KNIG C | 2011 | Taxon2011，60，5： | 1 |
| 17 | The corrosion behaviour of laser treated Ni-P alloy coatings on mild steel显示文摘 | García-Alonso M C Escudero M L López V | 1996 | Corrosion Science1996，38，： | 1 |
| 18 | Non-isothermal crystallization kinetics of poly(p-phenylene sulfide) 显示文摘 | López L C Wilkes G L | 1989 | Polymer1989，30，5： | 1 |
| 19 | Volatile compounds,quality parameters and consumer acceptance of ‘Pink Lady' apples stored in different conditions显示文摘 | López M L Villatoro C Fuent T | 2007 | Postharvest Biology and Technology2007，43，： | 1 |
| 20 | Xanthogranuloma on the penis of an adult:an unusual localization显示文摘 | L(o)pez V Molina I Monteagudo C | | 0，，03： | 1 |
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