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202篇 您的检索式:作者名="LA Anderson"
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1急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS 2017中华神经外科疾病研究杂志2017,16,6:8
2Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil.Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari 2019World Journal of Gastroenterology2019,25,38:2
3No association between hOGG1 ,XRCC1 ,and XPD polymorphisms and risk of reflux esophagitis, Barrett′s esophagus, or esophageal adenocareinoma: results from the factors influencing the Barrett′s adenocarcinoma relationship casecontrol study 显示文摘Ferguson HR Wild CP Anderson LA 2008Cancer Epidemiol Biomarkers Prey2008,17,3:1
4DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(Ⅱ) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity显示文摘Zwelling LA Anderson T Kohn KW 1979Cancer Res1979,39,21:1
5Interaction of vascular plants and vesicular-arbuscular mycorrhizal fungi across a soil moisture-nutrient gradient 显示文摘Anderson RC Liberta AE Dickman LA 1984Oecologia1984,64,1:1
6ACC/AHA guidelines for the martagement of patients with ST-elevation myocardial infarction-executive summary:port of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of patients with Acute Myocardial Infarction) 显示文摘Antman EM Anbe DT Armstrong PW Bates ER Green LA Hand M Hochman JS Krumholz HM Kushner FG Lamas GA Mullany CJ Ornato JP pearle DL Sloan MA Smith SCJr Alpert JS Anderson JL Faxon DP Fuster V Gibbons RJ Gregoratos G Halperin JL Hiratzka LF Hunt SA Jacobs AK American College of Cardiology American Heart Association Task Force on Practice Guidelines 2004Circulation2004,110,5:1
7Glucoseinduced oxidative stress in mesangial cells显示文摘Catherwood MA Powell LA Anderson P 2002Kidney Int2002,61,2:1
8Glucose-induced oxidative stress in mesangial cells显示文摘Catherwood MA Powell LA Anderson P 2002Kidney Int2002,61,2:1
9Metaanalysis of five reported studies on the relation of early coronary patency grades with mortality and outcomes after acute myocardial infarction显示文摘 Karagounis LA Califf RM 1996Am J Cardiol1996,78,:1
10Anti-inflammatory intestinal activity of Arctium lappa L. (Asteraceae) in TNBS colitis model显示文摘Ana Beatriz Albino de Almeida Marina Sánchez-Hidalgo Antonio Ramón Martín Anderson Luiz-Ferreira José Roberto Trigo Wagner Vilegas Lourdes Campaner dos Santos Alba Regina Monteiro Souza-Brito Catalina Alarcón de la Lastra 2013Journal of Ethnopharmacology2013,,1:1
11Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro显示文摘McTernan PG Harte AL Anderson LA 2002Diabetes2002,51,5:1
12Is male breast cancer similar or different than female breast cancer 显示文摘Anderson WF Althuis MD Brinton LA 2004Breast Cancer Res Treat2004,83,1:1
13The changing na- ture of rectus sheath haematoma: case series and literature review 显示文摘Fitzgerald JE Fitzgerald LA Anderson FE 2009Int J Surg2009,7,:1
14Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial显示文摘Pearce LA McClure LA Anderson DC 2014Lancet Neurol2014,13,12:1
15Non-steroidal anti-inflammatory drugs and the esophageal inflammation-metaplasia-adenocarcinoma sequence显示文摘Anderson LA Johnston BT Watson RG 2006Cancer Res2006,66,9:1
16Enhancement of graft-versus-tumor activity and graft-versus-host disease by pretransplant immunization of allogeneic bone marrow donors with a recipient-derived tumor cell vaccine 显示文摘Anderson LD Petropoulos D Everse LA 1999Cancer Res1999,59,7:1
17Site-specific regulation of oestrogen receptor-alpha and -beta by oestradiol in human adipose tissue 显示文摘Anwar A Mcternan PG Anderson LA 2001Diabetes Obes Metab2001,3,5:1
18A novel transcriptional repression domain mediates p21WAF1 induction of p300 transactivation显示文摘Snowden AW Anderson LA Webster GA 2000Mol Cell Biol2000,20,8:1
19Ten-to 15-year clinical and radiographic results for a compression molded monoblock elliptical acetabular component显示文摘Pouhsides LA Sioros V Anderson JA 0,,10:1
20Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro 显示文摘McTernan PG Harte AL Anderson LA 2002Diabetes2002,51,5:1
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