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| 1 | The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives显示文摘精索静脉曲张在精索以内被定义为内部阴囊的静脉和 pampiniform venus 丛的反常膨胀。如果精液分析没从青春期的男性被获得,当另外的症状不在时,主要临床的指示由许多泌尿科医师使用了建议修理是阴囊的萎缩。精索静脉曲张可以在与损害精子引起阴囊的萎缩的一些男性导致阴囊的损坏生产和减少的 Leydig 房间工作,当在另外的男性精索静脉曲张可以看起来不引起有病的效果时。在成年的人,精索静脉曲张经常在场、通过手术可改正,还外科的修理的可测量的好处根据 Cochrane 评论是细微的。当比肥沃的人更通常发生在不肥沃的人时,仅仅,有记录精索静脉曲张的 20% 人将受不了富饶问题。在青少年发现的大多数精索静脉曲张在平淡的体格检查期间被检测,并且预言与精索静脉曲张的青春期的介绍哪个将最终在青春期或成人生活显示出减少的阴囊的功能是困难的。作为在成年人,为在青少年的精索静脉曲张的处理的支柱是外科的修正。然而,不同于成年 varicocelectomy (microsurgical 途径是最普通) ,为青春期的精索静脉曲张的处理更经常是 laparoscopic。不过,治疗的目标是在青春期、成年的病人的一样。至于病人,并且什么类型治疗,,对待开始治疗是最好的争吵遗体。这评论将介绍青春期的精索静脉曲张的病原学,诊断和治疗的当前的理解。 | Koji Chiba Ranjith Ramasamy Dolores J Lamb Larry I Lipshultz | 2016 | Asian Journal of Andrology2016,18,2: | 14 |
| 2 | 高龄对男性生育力的影响显示文摘在过去的几十年里,现代社会的压力和期望使得育龄夫妇生育年龄总体推迟。已知女性在临近40岁时卵母细胞的产生将会明显减少,而高龄对男性精子生成能力的影响还知之甚少。男性生育年龄无明确限制,因而高龄对男性生育能力的影响还不完全清楚。本文将就目前已知的高龄对男性精子质量、生育能力和子代健康的影响进行综述,希望能在医生就男性推迟生育及高龄相关的风险咨询时起到一定的指导作用。 | Jason R Kovac Josephine Addai Ryan P Smith Robert M Coward Dolores J Lamb Larry I Lipshultz | 2013 | Asian Journal of Andrology2013,15,6: | 12 |
| 3 | Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction显示文摘在里面结合不孕, 0% 正常形式(NF ) 的反常严格的形态学是一个标准很快继续到在 vitro 授精(IVF ) 。自从没有数据,当前存在,我们与 0% NF 为人调查了结果没有帮助繁殖技术(艺术) 的使用,决定繁殖成功。有 0% NF 的 24 个人的一个队被识别(2010-2013 ) 随机与 ≥ 与 27 选择了人;是的 4% NF 控制。耐心的图表与联系并且管理同意的一块机构的评论板(IRB ) 的人一起被考察查明结果的电话问询表。在 2.5 年的一中部的后续时间以后,有 0% NF 的 29.2% 人没为他们的第一怀孕要求艺术(控制 =55.6% , P ≤0.05 ) 。当所有怀孕一起被分析时,有 0% NF 的人完成了 75% 没要求 IVF 的二十怀孕(控制 = 三十怀孕;76.7% 没要求 IVF ) 。人和女搭挡的平均年龄在有 0% NF 和 ≥ 的人之间是类似的; 4% NF。所有人有正常刺激滤泡的荷尔蒙(FSH ) ,睾丸激素,催乳激素,性别荷尔蒙绑定血球素(SHBG ) ,和 estradiol。尽管,当第一怀孕是一个自然概念(NC ) 时,全球精液参数在有 0% NF 的人是更坏的,有 0% NF (n = 7/7 ) 的人的 100% 并且 37.5% 控制(n = 3/8 ) 继续了经由 NC 有随后的怀孕。没有 IVF,有 0% NF 的人与 55.6% 控制相比在 29.2% 盒子中怀孕了。严格的形态学不应该被用来预言授精,怀孕,或实时出生潜力。在有 0% NF 的人,其他的形式应该被认为 IVF 以前立即。 | Jason R Kovac Ryan P Smith Miguel Cajipe Dolores J Lamb Larry I Lipshultz | 2017 | Asian Journal of Andrology2017,19,1: | 7 |
| 4 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014,6,10: | 6 |
| 5 | Sperm counts and sperm sex ratio in male infertility patients显示文摘在最近的年里,调查者在许多工业化国家向男出生的一个衰退比例注意了一个趋势。当人们忍受决定性的染色体时,它与授精或流产相关的女搭挡的角色可以也改变性比率。我们试图由直接检验他的精子的性染色体决定一个人的第二等的性比率(F1 产生) 。我们为在 situ 杂交(鱼) 经历了精液荧光的所有人检验了我们的男不孕诊所数据库。人口统计的病人和精液参数被记录。摆平 Chi 的分析被用来比较性比率(Y 染色体 / 总数染色体) 。Multivariable 逻辑回归被用来预言在财务以后拥有一个忍受 Y 精子为的机会人口统计并且精液参数。185 个人的一个总数经历了精子鱼。为全部队, Y 忍受染色体的精子的比例是 51.5 %。有不到 500 万个能动精子的人有 Y 忍受染色体的精子的一个显著地更低的比例(50.8 %) 与有更高的精子计数的人相比(51.6 %P=0.02 ) 。在 multivariable 调整以后,更高的精子集中,全部的能动精子计数和精液体积显著地增加了有 Y 的机会忍受染色体的精子(P< 0.01 ) 。作为一个人的精子生产衰落,那么做 Y 忍受染色体的精子的比例。因此,一个人的繁殖潜力可以预言他的能力到陛下男性后代。 | Michael L Eisenberg Lata Murthy Kathleen Hwang Dolores J Lamb Larry I Lipshultz | 2012 | Asian Journal of Andrology2012,14,5: | 3 |
| 6 | Counting your sperm before they fertilize: are sperm counts really declining?显示文摘 | Alexander W Pastuszak | 2013 | Asian Journal of Andrology2013,15,2: | 3 |
| 7 | Signal and construction mechanisms for activation of plant defenses against microbial attack显示文摘 | Lamb C J Lawton M A Dron M | 1989 | Cell1989,56,: | 2 |
| 8 | Recent advances in the genetics of testicular failure显示文摘不孕影响约 15% 夫妇,并且男因素为所有不孕的 30%-50% 负责。男不孕的最严重的形式是阴囊的失败,并且阴囊的失败的典型显型严重地被损害精子发生导致精子缺乏或严重 oligozoospermia。尽管阴囊的失败的病原学仍然保持糟糕理解,基因因素典型地是一个内在的原因。现代帮助繁殖技术革命化了男因素不孕的处理,允许生物父权被将另外不能成为到他们通过自然概念的孩子的父亲的许多人完成。因为基因畸形的传播的潜在的风险,因此,在男性识别基因畸形是批评的。最近,与另外的强烈研究一起,进行中的、整个染色体的途径在男不孕的基因研究逐渐地被使用了。在这评论,我们集中于阴囊的失败的遗传并且在男不孕的遗传的学习在进展上提供更改。 | Seung-Hun Song Koji Chiba Ranjith Ramasamy Dolores J Lamb | 2016 | Asian Journal of Andrology2016,18,3: | 2 |
| 9 | Expression ofa reflex of snapping/biting response to amino acids prior to the first exogenous feeding in salmonid alevins显示文摘 | Valentin(c)i(c) T B Lamb C F Caprio J | 1999 | Physiol Behav1999,67,4: | 1 |
| 10 | Not just another BI:faculty-librariancollaboration to guide students through the research process显示文摘 | STEIN L L LAMB J M | 1998 | Research Strategies1998,16,1: | 1 |
| 11 | Oviposition and larval establishment of Sitodiplosis mosellana (Diptera:Cecidomyiidae) on wheat (Gramineae) At different growth stages显示文摘 | Ding H Lamb R J | 1999 | The Canadian Entomologist1999,,131: | 1 |
| 12 | Elicitor induced and wound induced oxidative cross-linking of a proline rich plant-cell wall protein:a novel,rapid defense response显示文摘 | BRADLEY D J KJELLOOM P LAMB C J | 1992 | Cell1992,70,1: | 1 |
| 13 | Efficient immobi-lization of a cadmium chemosensor in a thin film:Generation of acadmium sensor prototype显示文摘 | Bronson R T Michaelis D J Lamb R D | 2005 | Org Lett2005,7,6: | 1 |
| 14 | Dislocations of the lunate with and without fracture of the scaphoid显示文摘 | Panting AL Lamb DW Noble J | 1984 | J Bone Joint Surg Br1984,66,3: | 1 |
| 15 | Assessment of intake from the diet显示文摘 | R Kroes D Müller J Lambe M.R.H L?wik J van Klaveren J Kleiner R Massey S Mayer I Urieta P Verger A Visconti | 2002 | Food and Chemical Toxicology2002,,2: | 1 |
| 16 | Heat shock protein antibody titers are reduced by statin therapy in dyslipidemic subjects: a pilot study显示文摘 | GHAYOUR-MOBARHAN M LAMB D J VAIDYA N | 2005 | Angiology2005,56,1: | 1 |
| 17 | Genetic dissection of mammalian fertility pathways显示文摘 | Matzuk M M Lamb D J | 2002 | Nature cell biology2002,8,: | 1 |
| 18 | The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver 显示文摘 | Eyal S Lamb J G Smith-Yockman M | 2006 | Br J Pharmacol2006,149,3: | 1 |
| 19 | A novel Pd/MgAlOx catalyst for NOX storage-reduction显示文摘 | SILLETTI B A ADAMS R T SIGMON S M NIKOLOPOULOS A SPIVEY J J LAMB H H | 2006 | Catal Today2006,114,1: | 1 |
| 20 | Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiqui- tin-conjugating activity to DNA damage sites 显示文摘 | Bailly V Lamb J Sung P | 1994 | Genes Dev1994,8,7: | 1 |