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643篇 您的检索式:作者名="LAWRENCE J A"
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1Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome显示文摘We report a case of virus-induced acute respiratory distress syndrome(ARDS) treated with parenteral vitamin C in a patient testing positive for enterovirus/rhinovirus on viral screening. This report outlines the first use of high dose intravenous vitamin C as an interventional therapy for ARDS, resulting from enterovirus/rhinovirus respiratory infection. From very significant preclinical research performed at Virginia Commonwealth Universitywith vitamin C and with the very positive results of a previously performed phase Ⅰ safety trial infusing high dose vitamin C intravenously into patients with severe sepsis, we reasoned that infusing identical dosing to a patient with ARDS from viral infection would be therapeutic. We report here the case of a 20-year-old, previously healthy, female who contracted respiratory enterovirus/rhinovirus infection that led to acute lung injury and rapidly to ARDS. She contracted the infection in central Italy while on an 8-d spring break from college. During a return flight to the United States, she developed increasing dyspnea and hypoxemia that rapidly developed into acute lung injury that led to ARDS. When support with mechanical ventilation failed, extracorporeal membrane oxygenation(ECMO) was initiated. Twelve hours following ECMO initiation, high dose intravenous vitamin C was begun. The patient's recovery was rapid. ECMO and mechanical ventilation were discontinued by day-7 and the patient recovered with no long-term ARDS sequelae. Infusing high dose intravenous vitamin C into this patient with virus-induced ARDS was associated with rapid resolution of lung injury with no evidence of post-ARDS fibroproliferative sequelae. Intravenous vitamin C as a treatment for ARDS may open a new era of therapy for ARDS from many causes.Alpha A Fowler Ⅲ Christin Kim Lawrence Lepler Rajiv Malhotra Orlando Debesa Ramesh Natarajan Bernard J Fisher Aamer Syed Christine DeWilde Anna Priday Vigneshwar Kasirajan 2017World Journal of Critical Care Medicine2017,6,1:9
2The reactions between Ca-based solids and gases representative of those found in a fluidized-bed incinerator显示文摘LAWRENCE A D BU J 2000Chemical Engineering Science2000,55,24:2
3The effect of salinity on growth and survival of Penaeus vannamei, with observations on the interaction of IHHN virus and salinity 显示文摘Bray W A Lawrence A L Leung-Trujillo J R 1994Aquaculture1994,122,23:1
4Observation on the decline in sperm quality of Penaeus serilferus under laboratory conditions 显示文摘Leung T J R Lawrence A L 1987Aquaculture1987,65,:1
5Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes显示文摘Dodds P N Lawrence G J Catanzariti A M 2006Proc Natl Acad Sci USA2006,103,:1
6The effects of ω3 fatty acids and coenzyme Q10 on blood pressure and heart rate in chronic kidney disease: a randomized controlled trial显示文摘Trevor A Mori Valerie Burke Ian B Puddey Ashley B Irish Christine A Cowpland Lawrence J Beilin Gursharan K Dogra Gerald F Watts 2009Journal of Hypertension2009,,9:1
7An overviewoftissue engineered bone显示文摘Charles A Vacanti MD Lawrence J 0,,:1
8The effects of feeding frequency on growth and reproduction in zebrafish (Danio rerio)显示文摘LAWRENCE C BEST J JAMES A 0,,368:1
9The Melampsora lini AvrL567 avirulence genes are expressed in haustoria and their products are recognized inside plant cells 显示文摘Dodds P N Lawrence G J Catanzariti A M 2004The Plant Cell2004,16,:1
10Toxic moieties in ruminal and duodenal digesta and in milk, and hepatic integrity in cattle given diets based on rapeseed meals of different glucosinolate con tents either untreated or treated with heat or formaldehyde显示文摘Subuh A M H Rowa T G Lawrence T L J 1995Animal Feed Science and Technology1995,52,:1
11Radiosensitization by gemcitabine显示文摘Lawrence T S Eisbruch A McGun C J 1999Oncology(Wiiliston Park)1999,13,105:1
12Non-ionic oil-in-water mieroemulsions: The effect of oil type on phase behaviour 显示文摘Warisnoicharoen W Lansley A B Lawrence M J 2000lnt J Pharm2000,198,:1
13Multi project scheduling with limited resources:A zero-one programming approach显示文摘Pritsker A Allan B Waiters Lawrence J 1969Management Science1969,16,1:1
14Heter-duplex molecules formed between allelic sequences cause nonparental RAPD bands显示文摘Aylifle M A Lawrence G J Ellis J G 1994Nucleic Acid Res1994,22,:1
15Haustorially expressed secreted proteins from flax rust are highly enriched for avirulence elicitors显示文摘Catanzariti A M Dodds P N Lawrence G J 2006Plant Cell2006,18,:1
16Determining Robust Impacts of Land-Use-Induced Land Cover Changes on Surface Climate over North America and Eurasia: Results from the First Set of LUCID Experiments显示文摘de Noblet-Ducoudré Nathalie Boisier Juan-Pablo Pitman Andy Bonan G B Brovkin V Cruz Faye Delire C Gayler V van den Hurk B J J M Lawrence P J van der Molen M K Müller C Reick C H Strengers B J Voldoire A 2012EN2012,,9:1
17Geochemical transformations during artificial groundwater re- charge:Soil-water interactions of inorganic constitu- ents显示文摘Juliet S J Lawrence A B Peter F 1999Water Resource1999,33,:1
18Haustorially expressed secreted proteins from flax rust are highly enriched for avirulence elicitors 显示文摘Catanzariti A M Dodds P N Lawrence G J 2006The Plant Cell2006,18,:1
19The N-terminal 85 amino acids of the Barley stripe mosaic virus gammab pathogenesis protein contain three zinc-binding motifs显示文摘Bragg J N Lawrence D M Jackson A O 2004Journal of Virology2004,78,14:1
20The future of wind forecasting and utility operations显示文摘Mark A Lawrence J Robert Z 2005IEEE Power Energy Magzine2005,6,3:1
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