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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Variability of environmental exposures to volatile organic compounds显示文摘 | STEPHEN M R LAWRENCE L K | 2004 | Journal of Exposure Science & Environmental Epidemiology2004，14，1： | 1 |
| 3 | Attenuation,persistence,and vaccine potential of an Edwardsiella ictaluri purA mutant显示文摘 | Lawrence M L Cooper R K Thune R L | 1997 | Infection and Immunity1997，65，11： | 1 |
| 4 | Subaperture testing of aspheres with annular zones显示文摘 | Liu Y M Lawrence G N Koliopoulos C L | 1988 | Appl Opt1988，27，21： | 1 |
| 5 | The use of 3-Ddose volume analysis to predict radiation hepatitis显示文摘 | Lawrence T S Ten Haken R K Kessler M L | 1992 | Int J Radiat Oncol Biol Phys1992，23，9： | 1 |
| 6 | Effects of dynamic exer- cise intensity on the activation of hormone-sensitive lipase in human skeletal muscle 显示文摘 | Watt M J George JF Lawrence L | 2003 | J Physiol2003，547，1： | 1 |
| 7 | Toxic moieties in ruminal and duodenal digesta and in milk, and hepatic integrity in cattle given diets based on rapeseed meals of different glucosinolate con tents either untreated or treated with heat or formaldehyde显示文摘 | Subuh A M H Rowa T G Lawrence T L J | 1995 | Animal Feed Science and Technology1995，52，： | 1 |
| 8 | Listetia monocytogenesserotype 4b strains belonging to lineages I and III possessdistinct molecular features 显示文摘 | Liu D Y Lawrence M L Gorski h | 2006 | Journal of Clinical Microbiology2006，44，1： | 1 |
| 9 | Effect of dietary phospholipid on essential fatty acid requirements and tissue lipid composition of Litopenaeus vannamei juveniles显示文摘 | GONZALEZ M L GATLINIII D M LAWRENCE A L | 2002 | Aquaculture2002，207，12： | 1 |
| 10 | A Technique for Using Composite DMSP/OLS 'City Lights' Satellite Data to Accurately Map Urban Areas显示文摘 | Imhoff M L Lawrence W T Stutzer D C | 1997 | Remote Sensing of Envi- ronment1997，61，3： | 1 |
| 11 | Cervical Ectopic Pregnancy显示文摘 | Lawrence M leeman MD Claire L | 2000 | Arch Faro Meal2000，9，： | 1 |
| 12 | Self-Organi-zation and Identification of Web Communities 显示文摘 | Flake G W Lawrence S Giles C L Coetzee F M | 2002 | IEEE Com-puter2002，35，3： | 1 |
| 13 | Detection of a novel high molecular weight subunit of glutenin in some Japanese hexaploid wheats显示文摘 | Payne P L Holt L M Lawrence G J | 1983 | Cereal Science1983，1，： | 1 |
| 14 | Mercury in the Chesapeake Bay显示文摘 | Mason R P Lawson N M Lawrence A L | 1999 | Marine Chemistry1999，65，： | 1 |
| 15 | Analyzing bioterror response logistics: the case of anthrax 显示文摘 | David L Craft Lawrence M Wein Alexander H Wilkins | 2005 | Management Science2005，，5： | 1 |
| 16 | Burial diagenesis of illite/smectite in shales and the origins of authigenic quartz and secondary porosity in sandstones显示文摘 | Lynch F L Lawrence E M Lynton S L | 1997 | Geochimica et Cosmochimica Acta1997，61，10： | 1 |
| 17 | Exploiting tractable substructures in intractable networks 显示文摘 | LAWRENCE K SAUL L JORDAN M | 1996 | Advances in Neural Information Processing Systems1996，8，： | 1 |
| 18 | Effect of dietary phospholipid on essential fatty acid requirements and tissue lipid composition of Litopenaeus vannamei juveniles显示文摘 | Gonz lez-F lix M L Gatlin III D M Lawrence A L | 2002 | Aquaculture2002，207，： | 1 |
| 19 | Detection of a novel high molecular weight subunit of glutenin in some Japa- nese hexaploid wheats显示文摘 | Payne P I Holt L M Lawrence G J | 1983 | Journal of Cereal Science1983，1，1： | 1 |
| 20 | A technique for using composite DMSP/OLS ' City Lights' satellite data to map urban area 显示文摘 | Imhoff M L Lawrence W T Stutzer D C | 1997 | Remote Sensing of Environment1997，，： | 1 |
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