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| 1 | Postpartum depression:A systematic review of the genetics involved显示文摘Postpartum depression is one of the most prevalent psychopathologies. Its prevalence is estimated to be between 10% and 15%. Despite its multifactorial etiology, it is known that genetics play an important role in the genesis of this disorder. This paper reviews epidemiological evidence supporting the role of genetics in postpartum depression(PPD). The main objectives of this review are to determine which genes and polymorphisms are associated with PPD and discuss how this association may occur. In addition, this paper explores whether these genes are somehow related to or even the same as those linked to Major Depression(MD). To identify gaps in the current knowledge that require investigation, a systematic review was conducted in the electronic databases Pub Med, LILACS and Sci ELO using the index terms 'postpartum depression' and 'genetics'. Literature searches for articles in peerreviewed journals were made until April 2014. PPD was indexed 56 times with genetics. The inclusion criteria were articles in Portuguese, Spanish or English that were available by institutional means or sent by authors upon request; this search resulted in 20 papers. Genes and polymorphisms traditionally related to MD, which are those involved in the serotonin, catecholamine, brain-derived neurotrophic factor and tryptophan metabolism, have been the most studied, and some have been related to PPD. The results are conflicting and some depend on epigenetics, which makes the data incipient. Further studies are required to determine the genes that are involved in PPD and establish the nature of the relationship between these genes and PPD. | Tiago Castro e Couto Mayra Yara Martins Brancaglion António Alvim-Soares Lafaiete Moreira Frederico Duarte Garcia Rodrigo Nicolato Humberto Corrêa Regina Amélia Lopes P Aguiar Henrique Vitor Leite | 2015 | World Journal of Psychiatry2015，5，1： | 5 |
| 2 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 3 | Development of metal oxide nanoparticles with high stability against particle growth using a metastable solid solution 显示文摘 | Leite E R Maciel A P Weber I T | 2002 | Adv Mater2002，14，： | 1 |
| 4 | Detection of field isolates of human and animal group C rotavirus by reverse transcription-polymerase chain reaction and digorigenin-labeled oligonucleotide probes显示文摘 | Alfieri A A Leite J P Alfieri A F | 1999 | J Vriol Methods1999，83，12： | 1 |
| 5 | Probabilistic wind farms generation model for reliability studies applied to brazilian sites显示文摘 | Leite A P Borges C L T Falcao D M | 2006 | IEEE Trans on Power Systems2006，21，4： | 1 |
| 6 | Preparation and characterization of ethanol-treated silk fibroin dense membranes for biomaterials application using waste silk fibers as raw material显示文摘 | NOGUEIRA G M RODAS A C D LEITE C A P | 2010 | Bio-Resource Technology2010，101，21： | 1 |
| 7 | Efficient preparation of polystyrene/silica colloidal nanocomposite particles by emulsion polymerization using a glycero|-functionalized silica sol显示文摘 | Schmid A Armes S P Leite C A P | 2009 | Lang-muir2009，25，4： | 1 |
| 8 | Symptomatic cysts of the cavum septi pellucidi and cavum vergae: The role of endoscopic neurosurgery in the treatment of four consecutive cases 显示文摘 | Fratzoglou M Grunert P Leite dos Santos A | 2003 | Minim Invasive Neurosurg2003，46，： | 1 |
| 9 | Current forces in tankers and bifurcation of equilibrium of turret systems:hydrodynamic model and experiments显示文摘 | Leite A J P Aranha J A P Umeda C | 1998 | Applied Ocean Research1998，20，： | 1 |
| 10 | Preparation of natural rubber-montmorillonite nanocomposite in aqueous medium: evidence for polymer-platelet adhesion 显示文摘 | VALADARES L F LEITE C A P GALEMBECK F | 2006 | Polymer2006，47，： | 1 |
| 11 | Evaluation of Mechanical Properties of Concrete with Copper Slag as Fine Aggregate 显示文摘 | Moura W A Goncalves J P Leite M B | 2009 | Rem-Revista Escola de Minas2009，62，2： | 1 |
| 12 | The influence of sintering process and atmosphere on the non-ohmic properties of SnO2-based varistor 显示文摘 | Leite E R Nascimento A M Bueno P R | 1999 | J Mater Sci Mater Electr1999，10，： | 1 |
| 13 | Biological and methodo- logical features of the measurement of S100B, a putative marker of brain injury显示文摘 | Goncalves C A Leite M C Nardin P | 2008 | Clin Biochem2008，41，1011： | 1 |
| 14 | The renin-angiotensin system in a rat model of hepatic fibrosis: evidence for a protective role of Angiotensin-(1-7) 显示文摘 | Pereira R M Dos Santos R A Teixeira M M Leite V H Costa L P da Costa Dias F L | 2007 | J Hepatol2007，46，： | 1 |
| 15 | Anti-inflammatory properties of extracts,fractions and lignans iso- lated from Phyllanthus arrtarus 显示文摘 | KASSUYA C A L LEITE D F P LUCILIA V D M | 2005 | Planta Medica2005，71，8： | 1 |
| 16 | Thalamic lesions in vascular dementia: low sensitivity of fluid-attenuated inversion recovery (flair) imaging 显示文摘 | Bastos Leite A J van Straaten EC Scheltens P | 2004 | Stroke2004，35，2： | 1 |
| 17 | Bayesian networks applied to failure diagnosis in power transformer显示文摘 | Quispe Carita A J Cambraia Leite L Pires Medeiros A P | 2013 | IEEE Latin America Transactions (Revista IEEE America Latina)2013，11，4： | 1 |
| 18 | Requirements Validation Through Viewpoint Resolution显示文摘 | J C S P Leite P A Freeman | 1991 | IEEE Trans Software Eng1991，17，12： | 1 |
| 19 | Probabilistic Load Flow Techniques Applied to Power System Expansion Planning 显示文摘 | Leite da Silva A M Ribeiro S M P Allan R N | 1990 | IEEE Transactions on Power Systems1990，5，4： | 1 |
| 20 | Rising Food Prices and Household Welfare: Evidence from Brazil in 2008 显示文摘 | FERREIRA FHG FRUTI?ERO A LEITE P G | 2013 | Journal of Agricultural Economics2013，64，1： | 1 |
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