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675篇 您的检索式:作者名="LEWIS R W"
    题名 作者 年代 出处 被引量
1Pancreatic cancer: Are 'liquid biopsies' ready for prime-time?显示文摘Pancreatic cancer is a disease that carries a poor prognosis. Accurate tissue diagnosis is required. Tumours contain a high content of stromal tissue and therefore biopsies may be inconclusive. Circulating tumour cells(CTCs) have been investigated as a potential 'liquid biopsy' in several malignancies and have proven to be of prognostic value in breast, prostate and colorectal cancers. They have been detected in patients with localised and metastatic pancreatic cancer with sensitivities ranging from 38%-100% using a variety of platforms. Circulating tumour DNA(ct DNA) has also been detected in pancreas cancer with a sensitivity ranging from 26%-100% in studies across different platforms and using different genetic markers. However, there is no clear consensus on which platform is the most effective for detection, nor which genetic markers are the most useful to use. Potential roles of liquid biopsies include diagnosis, screening, guiding therapies and prognosis. The presence of CTCs or ct DNA has been shown to be of prognostic value both at diagnosis and after treatment in patients with pancreatic cancer. However, more prospective studies are required before this promising technology is ready for adoption into routine clinical practice.Alexandra R Lewis Juan W Valle Mairead G Mc Namara 2016World Journal of Gastroenterology2016,22,32:5
2Necessary and sufficient for delayindependent stability of linear autonomous system显示文摘LEWIS R W ANDSON B D O 1980IEEE Trans on Automat Contr1980,25,:2
3Synthesis of new bis (acetylide)-substituted fluorene derivatives and their bimetallic and polymeric complexes显示文摘Lewis J Raithby P R Wong W Y 1998J Organomet Chem1998,556,:1
4Associated and non-associated visco-plasticity and plasticity in soil mechanics显示文摘Zienkiewicz O C Humpheson C Lewis R W 1975Geostechnique1975,25,4:1
5A finite element model of the squeeze casting process 显示文摘Lewis R W Ravindran K 2006International Journal of Numerical Methods for Heat & FluidFlow2006,16,5:1
6The Effect of Ceramic Fiber Coatings on the Room-Temperature Mechanical Behavior of Ceramic?Fiber Composites显示文摘R W Rice J R Spann D Lewis 1984Ceramic Engineering and Science Proceedings1984,5,78:1
7Fatty acid composition of some marine animals from various depths显示文摘LEWIS B R W 1967Journal of the Fisheries Research Board of Canada1967,24,16:1
8Associated and non-associated visco-plasticity and plasticity in soil mechanics 显示文摘Zienkiewicz O C Humpheson C Lewis R W 1975Geotechnique1975,25,4:1
9Associ- ated and non-associated viscoplasticity and plasticity in soil mechanics 显示文摘Zienkiewicz 0 C Humpheson C Lewis R W 1975Geotechnique1975,25,4:1
10Associated and NonAssociated Visco-Plasticity and Plasticity in Soil Mechanics显示文摘Zienkiewicz O C Humphson C Lewis R W 1975Géotechnique1975,25,4:1
11Associated and non-associated visco-plasticity and plasticity in soil mechanics显示文摘ZIENKIEWICZ O C HUMPHESON C LEWIS R W 1975Geotechnique1975,25,4:1
12Associated and non-associated visco-plasticity and plasticity in soil mechanics显示文摘ZIENKIEWICZ O C HUMPHESON C LEWIS R W 1975Geotechnique1975,25,4:1
13Associated and non-associated visco-plasticity and plasticity in soil mechanics 显示文摘Zienkiewicz O C Humpheson C Lewis R W 1975Geotechnique1975,25,4:1
14Why you should consider object-oriented programming techniques for finite element methods 显示文摘Cross J T Masters I Lewis R W 1999International Journal of Numerical Methods for Heat & Fluid Flow1999,9,3:1
15Vertical nitrite fluxes in the oligotrophic ocean显示文摘Lewis M R Harrison W G Oakey N S 1986Science1986,234,:1
16Tackling antibiotic resistance显示文摘Bush K Courvalin P Dantas G Davies J Eisenstein B Huovinen P Jacoby GA Kishony R Kreiswirth BN Kutter E Lerner SA Levy S Lewis K Lomovskaya O Miller JH Mobashery S Piddock LJ Projan S Thomas CM Tomasz A Tulkens PM Walsh TR Watson JD Witkowski J Witte W Wr 0,,:1
17Modeling of substitutionin SAPO-5 and SAPO-34 molecular sieves 显示文摘Sastre G Lewis D W Catlolw C R 1997Journal of Physical Chenistry1997,101,27:1
18Numerical comparison of a deformable discrete element model and an equivalent continuum analysis for the compaction of ductile porous material显示文摘 Ransing R S Lewis R W 2001Computers and Structures2001,79,:1
19A fully coupled consolidation model of the subsidence of Venice显示文摘Lewis R W Schrefler B 1978Water Resources Research1978,14,2:1
20Mercury Levels in Eggs, Tissues, and Feathers of Herring Gulls Larus argentatus From the German Wadden Sea Coast 显示文摘LEWIS S A BECKER P H FURNESS R W 1993Environmental Pollution1993,80,3:1
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