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279篇 您的检索式:作者名="LONDON S"
    题名 作者 年代 出处 被引量
1METAMORPHIC MECHANISMSAND THEIR CONFIGURATION MODELS显示文摘The concept of metamorphic mechanisms is presented, configuration models and configuration transformations relating to a set of new matrix operations are discussed and proposed. The configuration of a metamorphic mechanism reflects the connectivity change in the mechanism during motions which results in mobility change and presents the characteristics of the mechanism which is discussed in various applications particularly in decorative artifacts. The characteristics is further investigated with mobility analysis.Dai Jiansheng (Department of Mechanical Engineering, School of Physical Sciences and Engineering, King’s College, University of London,Strand,London WC2R 2LS, United kingdom) Zhang Qixian (Robotics Research Institute,Beijing University of Aeronautics and 2000Chinese Journal of Mechanical Engineering2000,13,3:61
2Crank conditions and rotatability of 3-RRR planar parallel mechanisms显示文摘This paper investigates the rotatability of planar parallel mechanisms by revealing the crank conditions that relate to link parameters.The paper extends the theorem of assemblability and the rotatability criterion and applies these criteria to parallel mechanisms in investigating the crank conditions of a parallel mechanism,leading to classification of three types of crank existing conditions including three-crank’s,six-crank’s and nine-crank’s of 3-RRR planar parallel mechanisms.The results are summarized as constraint conditions in relation with link parameters with a concluding table and case studies.LI RuiQin 1 &DAI Jian S 2 1 College of Mechanical Engineering and Automation,North University of China,Taiyuan 030051,China 2 Department of Mechanical Engineering,King’s College London,University of London,WC2R 2LS,UK 2009Science China(Technological Sciences)2009,52,12:12
3阿片成瘾者中的人格障碍问题显示文摘本文采用多种人格障碍筛查表对接受戒毒治疗的80例阿片成瘾者进行了测查。结果显示,各种人格障碍(personalitydisorders,PDs)的现患率为86%,其中戏剧性PD、依赖性PD、回避性PD和边缘性PD各分别占44%、36%、35%和76%。具有统计学意义的多种PD为:(1)依赖性-回避性(OR值=13.9;95%可信限范围=4.55,42.83);(2)戏剧性-依赖性(OR值=2.8;95%可信限范围=1.11,7.26);(3)边缘性-戏剧性(OR值=5.5;95%可信限范围=1.45,20.87);(4)边缘性-依赖性(OR值=3.9;95%可信限范围=1.04,15.04)。此结果提示,在阿片成瘾者中存在着各种严重的人格障碍。Adenekan Oyefeso, Hamid Ghodse, Carmel Clancy, Vanessa Crawford, Stephen Byrne(Research Evaluation and Monitoring Unit Department of Psychiatry of Addictive Behaviour St George’s Hospital Medical School London SW17 ORE) 1998中国药物依赖性杂志1998,7,2:6
4颈总动脉内径与心血管事件及死亡风险研究:4项队列研究的汇总分析显示文摘颈动脉内径增加是动脉重构的表现,且可能是心血管病的危险因素。研究者评估颈动脉内径与脑卒中、冠状动脉性心脏病、心血管病及全因死亡的关系,并探讨与血压有关的中膜增厚、动脉僵硬、动脉壁应力及动脉硬化等动脉重构过程能否解释此关系。Sedaghat S van Sloten TT Laurent S London GM Pannier Kavousi M Mattace-Raso F Franco OH Boutouyrie P Ikram MA Stehouwer CDA 赵狄 练桂丽 2018中华高血压杂志2018,26,7:4
5Orientation angle rotatability of planar serial n-link manipulators显示文摘This paper presents a new method of analyzing the orientation angle rotatability of a planar serial n-link manipulator by examining the rotatability of its virtual equivalent mechanism.Workspace orientation boundary region decomposition is proposed based on the polynomial discriminant derived from a serial three-link manipulator.Orientation angle workspace indicates a set of angle ranges by which the end-effector can reach with certain orientation for every point in the reachable position workspace.By introducing a virtual equivalent mechanism,the open-chain kinematic problem is converted into a close-chain mechanism,and the Grashof-type condition is used to examine the rotatability of the end-effector link.The reachable position workspace can be divided into several Grashof intervals and non-Grashof intervals based on the extreme positions and singular configurations of a manipulator.The derived equations in this paper can be used to calculate the variation rule of the orientation angle workspace of any given planar serial n-link manipulator on the basis of its link parameters.The orientation angle rotatability of a seven-link serial manipulator is solved by the proposed method and graphical representations of the orientation angle workspaces are mapped onto a three-dimensional coordinate system.The theoretical approach has practical significance for the design of a highly dexterous serial n-link manipulator with proposed link relations.LI RuiQin1,XIAO DengHong1 & DAI Jian S2 1 College of Mechanical Engineering and Automation,North University of China,Taiyuan 030051,China 2 Department of Mechanical Engineering,King’s College London,University of London,London WC2R 2LS,UK 2010Science China(Technological Sciences)2010,53,6:2
6Taxol inhibits stretch-induced electrophysiological alterations in isolated rat hearts with acute myocardial infarction显示文摘Mechanosensitive channels have been determined to work as transducers of mechanoelectric feedback in the heart, which is associated with the generation of arrhythmias. Recent studies have investigated the role of the cytoskeleton in ion channels control. This study explored the ability of taxol to inhibit stretch-induced electrophysiological alterations in the ischemic myocardium. Thirty-two Wistar rats were randomly divided into four groups: normal control group (n=9), taxol group (n=7), myocardial infarction (MI) group (n=9), and MI+taxol group (n=7). After Langendorff perfusion, the isolated hearts were stretched for 5 s by balloon inflation to 0.2 or 0.3 mL. The effects of stretching on 90% monophasic action potential duration (MAPD90), premature ventricular beats (PVB), and ventricular tachycardia (VT) were observed for 30 s. Stretching increased MAPD90 in both the normal control and MI groups, but MAPD90 increased more in the MI group for the same degree of stretch. Taxol (5 μmol L?1) had no effect on MAPD90 under baseline, unstretched conditions, but MAPD90 in the taxol group was slightly increased after stretching compared with the normal control group (P>0.05). However, taxol reduced MAPD90 in infarcted myocardium (P<0.05 at V=0.3 mL). The incidences of PVB and VT in the MI group were higher than in the normal control group (both P<0.01). Taxol had no effect on the occurrence of arrhythmias in normal myocardium, but it inhibited PVB and VT in infarcted hearts (both P<0.01). Thus changes in MAPD and the occurrence of arrhythmias caused by mechanical stretching of the myocardium could be inhibited by taxol in isolated rat hearts during AMI, indicating the involvement of tubulin in mechanoelectric feedback in AMI.CAO JunXian1, FU Lu1, SUN DianJun2, XIE RongSheng1, ZHOU Jue3 & QU Fan4 1Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China 2Chinese Research Center for Endemic Disease Control, Key Laboratory of Etiological Epidemiology, Ministry of Health (23618504), Harbin Medical University, Harbin 150081, China 3Pharmacy Department, King’s College London, Franklin-Wilkins Building, 150 Stamford Street, London, UK 4The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China 2010Science China(Life Sciences)2010,53,8:2
7Association of bone activity, calcium load, aortic stiffness, and calcificationsin ESRD 显示文摘London G M Marchais S J Guerin A P 2008J Am Soc Nephrol2008,19,9:1
8Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Ange-les County显示文摘 A K Daly J B S Leathar 1997Carcinogenesis1997,18,:1
9Differentiating the effects of fine and coarse particles on daily mortality in Shanghai,China显示文摘Kan H D London S J Chen G H 0,,03:1
10Genetic polymorphism of XRCC1 and lung cancer risk among African-Americans and Caucasians显示文摘David-Beabes G L London S J 2001Lung Cancer2001,34,3:1
11Effects of ad- hesive drapes on contamination of operation wounds 显示文摘LILLY H A LONDON P S LOWBURY E J L 1970Lancet1970,,:1
12Residential magnetic field exposure and breast cancer risk : a nested case-control study from a multiethnic cohort in Los Angeles County, California 显示文摘LONDON S J POGODA JM HWANG KL 2003Am J Epidemiol2003,158,10:1
13Arterial stiffening and vascular calcifications in end-stage renal disease显示文摘Guerin A P London G M Marchais S J 2000Nephrol Dial Transplant2000,15,7:1
14Cloud comput- ing adoption and usage in community colleges 显示文摘BEHREND T S WIEBE E N LONDON J E 2011Behaviour & Infor- mation Technology2011,30,2:1
15Langerhans cell histiocytosis in a premature baby presenting with skin-isolated disease: case report and literature review显示文摘Aviner S Ronen M London D 2008Acta Paediatr2008,97,12:1
16Mycoplasma pneumonia In- fection:A Possible Trigger for Immune Thrombocytopenia显示文摘Aviner S Miskin H London D 2011In- dian J Hematol Blood Transfus2011,27,1:1
17Family history and the risk of early-onset persistent, early-onset transient, and late-onset asthma显示文摘London S J James G W Avol E 2001Epidemiology2001,12,:1
18Treatment of canine osseous tumors with photodynamic therapy: a pilot study 显示文摘Burch S London C Seguin B 2009Clin Orthop Relat Res2009,467,4:1
19Notification of pesticide poi- soning in the western Cape, 1987 - 1991 显示文摘London L Ehrlich RI Rafudien S 1994S Afr Med1994,84,:1
20Cardiac disease in chronic uremia:pathogenesis显示文摘 Parfrey P S 1997Adv Ren Replace Ther1997,4,3:1
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