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| 1 | Pancreatic ductal adenocarcinoma: Risk factors, screening, and early detection显示文摘Pancreatic cancer is the fourth most common cause of cancer-related deaths in the United States, with over 38000 deaths in 2013. The opportunity to detect pancreatic cancer while it is still curable is dependent on our ability to identify and screen high-risk populations before their symptoms arise. Risk factors for developing pancreatic cancer include multiple genetic syndromes as well as modifiable risk factors. Genetic conditions include hereditary breast and ovarian cancer syndrome, Lynch Syndrome, familial adenomatous polyposis, Peutz-Jeghers Syndrome, familial atypical multiple mole melanoma syndrome, hereditary pancreatitis, cystic fibrosis, and ataxia-telangiectasia; having a genetic predisposition can raise the risk of developing pancreatic cancer up to 132-fold over the general population. Modifiable risk factors, which include tobacco exposure, alcohol use, chronic pancreatitis, diet, obesity, diabetes mellitus, as well as certain abdominal surgeries and infections, have also been shown to increase the risk of pancreatic cancer development. Several largevolume centers have initiated such screening protocols, and consensus-based guidelines for screening high-riskgroups have recently been published. The focus of this review will be both the genetic and modifiable risk factors implicated in pancreatic cancer, as well as a review of screening strategies and their diagnostic yields. | Andrew E Becker Yasmin G Hernandez Harold Frucht Aimee L Lucas | 2014 | World Journal of Gastroenterology2014，20，32： | 24 |
| 2 | On the Measurement of Stress-strain Curves by Spherical Indentation显示文摘 | E G Herbert G M Pharr W C Oliver B N Lucas J L Hay | 2001 | Thin Solid Films2001，，： | 1 |
| 3 | Haemoglobin levels do not correlate with the extent of coronary artery disease: results from a large cohort study显示文摘 | De Luca G Secco GG Cassetti E | 2014 | Coron Artery Dis2014，25，6： | 1 |
| 4 | Calculation of Mie derivatives显示文摘 | Grainger R G Lucas J Thomas G E | 2004 | Appl Opt2004，43，： | 1 |
| 5 | Review of small specimen test techniques for irradiation testing显示文摘 | Lucas G E | 1990 | Metallurgical Transactions A1990，21，： | 1 |
| 6 | Benefits from small molecule ad-ministration as compared with abciximab among patients with ST-seg-ment elevation myocardial infarction treated with primary angioplasty : ameta-analysis显示文摘 | De Luca G Ucci G Cassetti E | 2009 | J Am Coll Cardiol2009，53，： | 1 |
| 7 | 显示文摘 | Nagorka M S Levi C G Lucas G E | 1991 | Materials Science Engineering A1991，142，2： | 1 |
| 8 | Dinosaur skin impressions from the Upper Cretaceous Ringbone Formation, southwestern New Mexico显示文摘 | Anderson B G Barrick R E Lucas S G | 1998 | Joumal of Vertebrate Paleontology1998，18，： | 1 |
| 9 | Poly ( ethylene-co-vinylacetate) ( EVA) as wax in hibit or of a Brazili an crude oil: oilviscosity, pour point and phase behavior of organic solutions 显示文摘 | Machado A L C Lucas E F Gonzalez G | 2001 | Journal of Petroleum Science and Engineering2001，32，234： | 1 |
| 10 | Assessment of polymeric flocculants in oily water systems显示文摘 | Gonzalez G Lucas E F | 2005 | Colloid Polym Sci2005，283，： | 1 |
| 11 | The draft genome of watermelon (Citrullus lanatus ) and reseqnencing of 20 diverse accessions显示文摘 | Guo S G Zhang J G Sun H H Salse J Lucas W J Zhang H Y Zheng Y Mao L Y Ren Y WangZ W Min J M Guo X S Murat F Ham B K Zhang Z L Gao S Huang M Xu Y M Zhong S L Bombarely A Mueller L Zhao H He H Q Zhang Y Zhang Z H Huang S W Tan T Pang E Lin K Hu Q Kuang H H Ni P X Wang B Liu J G Kou Q H Hou W J Zou X H Jiang J Gong G Y Klee K Schoof H Huang Y Hu X S Dong S S Liang D Q Wang J Wu K Xia Y Zhao X Zheng Z Q Xing M Liang X M Huang B Q Lv T Wang J Y Yin Y Yi H P Li R Q Wu M Z Levi A Zhang X P Giovannoni J Wang J Li YF Fei Z J Xu Y | 2013 | Nature genetics2013，45，1： | 1 |
| 12 | Risk profile and benefits from Gp Ⅱ b Ⅲ a inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials 显示文摘 | de Luca G Navarese E Marino P | 2009 | Eur Heart J2009，30，22： | 1 |
| 13 | Recent progress in understandingreactor pressure vessel steel embrittlement显示文摘 | Odette G R Lucas G E | 1998 | Radiat Eft Defects Solids1998，114，： | 1 |
| 14 | The evolution of mechanical property change in irradiated austenitic stainless steels显示文摘 | Lucas G E | 1993 | Journal of Nuclear Materials1993，206，23： | 1 |
| 15 | The translocation of 14C- photosynthate from leaves显示文摘 | Lucas E O Milbourn G M Whitford P N | 1976 | Ann Appl Biol1976，83，： | 1 |
| 16 | Poly (ethylene-co-vinyl acetate)(EVA)as wax inhibitor of a Brazilian crude oil:Oil viscosity, pour point and phase behavior of organic solutions显示文摘 | MACHADO A L C LUCAS E F GONZáLEZ G | 2001 | Journal of Petroleum Science and Engineering2001，32，2： | 1 |
| 17 | Benefits from small molecule administration as compared with abciximab among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: A meta-analysis显示文摘 | De Luca G Ucci G Cassetti E | 2009 | J Am Coll Cardiol2009，53，18： | 1 |
| 18 | Some recent innovations in small specimen testing 显示文摘 | Odette G R He M Gragg D Klingensmith D Lucas G E | 2002 | Journal of Nuclear Materials2002，，： | 1 |
| 19 | Improved early diagnosis of Pseudomonas aeruginosa by rea|-time PCR to prevent chronic eolonisation in a paediatric cystic fibrosis populatio显示文摘 | Mceulloch E Lucas C Ramage G | 2011 | J Cyst Fi- bros2011，10，1： | 1 |
| 20 | The fracture resistance of directionally solidified dual-phase NiAl reinforced with refractory metals显示文摘 | Heredia F E He M Y Lucas G E etal | 1993 | Acta Metall1993，41，： | 1 |
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