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| 1 | Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBDs) are chronic disorders of modern society, requiring management strategies aimed at prolonging an active life and establishing the exact etiology and pathogenesis.These idiopathic diseases have environmental, genetic,immunologic, inflammatory, and oxidative stress components. On the one hand, recent advances have shown that abnormal immune reactions against the microorganisms of the intestinal flora are responsible for the inflammation in genetically susceptible individuals. On the other hand, in addition to T helper cell-type(Th) 1 and Th2 immune responses,other subsets of T cells, namely regulatory T cells and Th17 maintained by IL-23 are likely to develop IBD. IL-23 acts on innate immune system members and also facilitates the expansion and maintenance of Th17 cells. The IL-17/IL-23 axis is relevant in IBD pathogenesis both in human and experimental studies. Novel biomarkers of IBD could be calprotectin,microRNAs, and serum proinflammatory cytokines.An efficient strategy for IBD therapy is represented by the combination of IL-17 A and IL-17 F in acute IL-17 A knockout TNBS-induced colitis, and also definite decrease of the inflammatory process in IL-17 F knockout, DSS-induced colitis have been observed.Studying the correlation between innate and adaptive immune systems, we hope to obtain a focused reviewin order to facilitate future approaches aimed at elucidating the immunological mechanisms that control gut inflammation. | Cristina-Sorina Cǎanǎ Ioana Berindan Neagoe Vasile Cozma Cristian Magdas Flaviu Tǎbǎan Dan Lucian Dumitrasu | 2015 | World Journal of Gastroenterology2015，21，19： | 37 |
| 2 | Combined contrast-enhanced power Doppler and real-time sonoelastography performed during EUS, used in the differential diagnosis of focal pancreatic masses (with videos)显示文摘 | Adrian S?ftoiu Sevasti?a Iordache Dan Ionu? Gheonea Carmen Popescu Anca Malo? Florin Gorunescu Tudorel Ciurea Alexandru Iordache Gabriel Lucian Popescu Cǎtǎlin Manea | 2010 | Gastrointestinal Endoscopy2010，，4： | 2 |
| 3 | Nearest interval, triangular and trapezoidal approximation of a fuzzy number preserving ambiguity显示文摘 | Adrian I B Lucian C | 2012 | International Journal of Approximate Reasoning2012，53，： | 1 |
| 4 | Characterization and remediation of soils contaminated with uranium显示文摘 | MARIA G LUCIAN V P IGOR C | 2009 | Journal of Hazardous Materi- als2009，163，： | 1 |
| 5 | A multi-scale approach to improve reservoir charac- terization and forecasting: the Albacora Field (deep water offshore Brazil) study显示文摘 | Luciane B C Alberto cla S B Cristiano L S | 2001 | Petroleum Geosci- ence2001，7，5： | 1 |
| 6 | Production of biomass and nutraceutical compounds by Spirulina platensis under different temperature and nitrogen regimes 显示文摘 | Luciane M C Christian O R Carolina R R | 2007 | Bioresource Technology2007，，： | 1 |
| 7 | HIV-associated Pneumocystis pneumonia显示文摘 | Laurence H Adithya C Lucian DJ | 2011 | Proc Am Thorac Soc2011，8，11： | 1 |
| 8 | Combined contrast-enhanced power Doppler and real-time sonoelastography performed during EUS, used in the differential diagnosis of focal pancreatic masses (with videos)显示文摘 | Adrian S?ftoiu Sevasti?a Iordache Dan Ionu? Gheonea Carmen Popescu Anca Malo? Florin Gorunescu Tudorel Ciurea Alexandru Iordache Gabriel Lucian Popescu Cǎtǎlin Manea | 2010 | Gastrointestinal Endoscopy2010，，4： | 1 |
| 9 | Corpotate Financing and lnvesmtent Desions when Firm Have Information That investors do Not have显示文摘 | MYERS S C MAJLUF N S LUCIAN | 1984 | Jounral of Financial Economies1984，，13： | 1 |
| 10 | Enhanced xylitol production by precultivation of Candida guilliermondii cells in sugarcane bagasse hemicellulosic hydrolysates显示文摘 | Rita C L B Rodrigues Luciane Sene Gilvane S Matos | 2006 | Current Microbiology2006，53，： | 1 |
| 11 | Shunt Active Power Filter Topology Based on Parallel Interleaved Inverters显示文摘 | Asiminoaei Lucian Aeloíza Eddy C Enjeti Prasad N | | 0，，03： | 1 |
| 12 | An electrochemical-based fuel-cell model suitable for electrical engineering automation approach显示文摘 | JEFERSON C M FELIX A F LUCIANE N C | 2004 | lEEE Tran of Industrial Electronics2004，51，5： | 1 |
| 13 | Enhanced xylitol production by precultivation of Candida guilliermondii cells in sugarcane bagasse hemicellulosic hydrolysate显示文摘 | Rita C L B R Luciane S Gilvane S M | 2006 | Curr Microbiol2006，53，1： | 1 |
| 14 | Total joint arthroplasty in pa-tients with chronic renal disease: Is it worth the risk- 显示文摘 | Lucian C Andrew J Christopher T | 2015 | TheJournal of Arothroplasty2015，30，9： | 1 |
| 15 | New aspects on atrazine biodegradation显示文摘 | LUCIANE S ATTILIO C | 2010 | Bra-zilian Archives of Biology and Techonlogy2010，53，2： | 1 |
| 16 | Use and misuse in the application of the phytoplankton functional classification:a critical review with updates显示文摘 | JUDIT P LUCIANE O C LUIGI N F | 2009 | Hydrobiologia2009，621，1： | 1 |
| 17 | Vibrios dominate as culturable nitrogen-fixing bacteria of the Brazilian coral Mussismilia hispida显示文摘 | Luciane A Brocchi M Cristiane C | 2008 | Systematic and Applied Microbiology2008，31，： | 1 |
| 18 | Proteolytic regulationof Forkhead transcription factor F0X03a bycaspase-3 - like proteases显示文摘 | Charvet C Alberti I Lucian F | 2003 | Oncogene2003，22，29： | 1 |
| 19 | Determination of phenylbutazone and oxyphenbutazone in plasma and urine sample of horse by high-performance liquid chromatography and gas chromatography-mass spectrometry 显示文摘 | Luciane M R Maristela H A Myriam C S | 1996 | Journal of Chromatography B1996，678，： | 1 |
| 20 | Characterization and re- mediation of soils contaminated with uranium显示文摘 | Maria G Lucian V P Igor-Cretes C | 2009 | Jouranl of Hazardous Materials2009，163，23： | 1 |
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