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| 1 | 卫生政策分析:概念和方法的思考与挑战显示文摘许多专家学者就卫生政策分析开展了大量研究,但很少关注如何进行政策分析以及需要什么样的研究设计、理论和方法。本文着眼于卫生政策分析的环境以及面临的挑战,借鉴中低收入国家中一些卫生政策分析的框架、理论、方法和设计,列举了最近的研究案例,并探讨了案例研究的意义以及研究设计的必要性,发现卫生政策研究者的角色、反思和定位在研究过程中非常重要。最后从理论、方法学和研究人员的反思等角度提出了促进卫生政策分析的建议。 | Gill Walt Jeremy Shiffman Helen Schneider Susan F Murray Ruairi Brugha Lucy Gilson | 2012 | 中国卫生政策研究2012，5，12： | 3 |
| 2 | Analyzing the H19-and T65-epitopes in 38 kd phosphory-lated protein of Marek's disease viruses and comparing chicken immunological reactions to viruses point-mutated in the epitopes显示文摘DNA sequencing analysis in 38 kd phosphorylated protein (pp38) ORF of Marek's disease viruses (MDV) indicated that all tested 10 virulent strains with different pathotypes had 'A' at base #320 and glutamine at aa#107 while reacted with monoclonal antibody (Mab) H19 in indirect fluorescence antibody test (IFA). However, vaccine strain CVI988 had 'G' at base#320 and arginine at aa#107 instead, when it was negative in IFA with Mab H19. Some strains were also reactive with Mab T65 in IFA while there was 'G' at base #326 and glycine at aa#109, but the other strains, which had 'A' at base #326 and glutamic acid at aa#109, did not react with Mab T65. By comparison of CVI988 to its point mutants CVI/rpp38(AG) and CVI/rpp38(AA) with 1 or 2 base(s) changes at bases #320 and /or #326 of pp38 gene for their reactivity with Mab H19 and T65, it was confirmed that the glutamine at aa#107 and glycine at aa#109 were critical to epitopes H19 and T65 respectively. Immuno-reactions to MDV were compared in SPF chickens inoculated with cloned CVI988 and its mutant CVI/rpp38(AG). It was found that antibody responses to MDV in chickens inoculated with CVI/rpp38(AG) were delayed and significantly lower than that in chickens inoculated with the native CVI988. By differential comparison of antibody titers to different antigens, a third epitope specific to CVI988 and dependent on arginine at aa#107 was suggested to be responsible for the big difference in antibody responses induced by native CVI988 and its mutant. | Lee Lucy F | 2004 | Science China(Life Sciences)2004，47，1： | 2 |
| 3 | 马立克氏病病毒MEQ蛋白对MDV增殖影响的研究显示文摘在马立克氏病病毒 MDV致病机理的研究中 ,弄清致病基因 meq与病毒增殖之间的关系及其分子机制是十分重要的基础。以重组反转录病毒 (RCAS meq)感染鸡胚成纤维细胞 (CEF) ,使源于 MDV强毒参考株 (v MDV) GA株的 meq基因表达于宿主细胞内 ,然后再用 GA株感染这些细胞。通过利用 MDV强毒株特异的抗 pp3 8单克隆抗体所进行的“黑斑”试验以确定 MDV的增殖水平 ,并与未接种 RCAS meq的CEF进行比较。研究结果发现 ,细胞内表达的 meq基因产物可促进 GA株于体外培养细胞中的感染与增殖(病毒斑数增多 )。根据试验的结果 ,作者认为 meq基因在感染细胞内的表达水平是 MDV增殖以及进而能致病。 | 韦平 Lucy F Lee | 2002 | 广西农业生物科学2002，21，1： | 2 |
| 4 | A prospective comparative study of MR sialography and conventional sialography of salivary duct disease显示文摘 | Varghese JC Thornton F Lucy BC | 1999 | AJR1999，173，8： | 1 |
| 5 | Messenger ribonucleic acid for insulin-like growth factors-I and -II, insulin-like growth factor-binding protein-2, gonadotropin receptors, and steroidogenic enzymes in porcines follicles显示文摘 | Yuan W Lucy M C Smith M F | 1996 | Biology of Reproduction1996，，55： | 1 |
| 6 | Quality of reclaimed waters:a public health need for source tracking of wastewater-derived protozoan enteropathogens in engineered wetlands显示文摘 | Thaddeus K Graczyk T K Lucy F E | 2007 | Transactions of the Royal Society of Tropical Medicine and Hygiene2007，101，6： | 1 |
| 7 | The Introduction of Toronto Index Participation Units and Arbitrage Opportunities in the Toronto 35 Index Option Market显示文摘 | Ackert Lucy F Yisong S.Tian | | 0，，04： | 1 |
| 8 | Messenger ribonucleic acid for insulin-like growth factor-1 and factor-2,insulin-like growth factor binding protein-2,gonadrroping receptors and steroidogenic enzyrme in porcine follicles显示文摘 | Lucy M C Smith M F | 1996 | Biol Reprod1996，55，： | 1 |
| 9 | Compara- tive evaluation of vaccine efficacy of recombinant Marek's disease virus vaccine lacking Meq oncogene in commercial chickens显示文摘 | Lucy F Lee K S Kreager J Arango | 2010 | Vaccine2010，28，5： | 1 |
| 10 | Messenger rivonucleic acid for insulin-like growth factor-binding protein-2,gonadotropin receptors,and steroidogenic enzymes in porcine follicles显示文摘 | Lucy M C Smith M F | 1996 | Biology of Reproduction1996，55，： | 1 |
| 11 | Effect of homologous and heterologous prime boost on the immune response to recombinant plague antigens显示文摘 | Audrey G Lucy C F John D | 2005 | Vaccine2005，23，： | 1 |
| 12 | Relationship between follicle size at insemination and pregnancy success 显示文摘 | PERRY G A SMITH M F LUCY M C | 2005 | PNAS2005，102，14： | 1 |
| 13 | In vitro assay of mitogen stimulation of avian peripheral lymphocytes显示文摘 | Lucy F L | 1974 | Avian Diseases1974，18，4： | 1 |
| 14 | Complication rates following operative treatment of calcaneus fractures显示文摘 | Nelson SH Eugene F Lucie K | 2011 | Foot Ankle Surg2011，17，： | 1 |
| 15 | Modified alaminosilicates as low-cost sorbents of As ( Ⅲ ) from anoxic groundwater 显示文摘 | Barbora D Lucie F Grygar T | 2009 | J Hazard Mater2009，165，13： | 1 |
| 16 | Extraction of ribosomal RNA and genornic DNA from soil for studying the diversity of the indigenous bacterial community 显示文摘 | Gabriela F D Alexandre S R Lucy S A C | 1998 | J Microbiol Meth1998，32，： | 1 |
| 17 | Molecular identification of microo rganisms associated with parthenogenesis 显示文摘 | Breeuwer J AJ Lucy R F Werren J H | 1993 | Nature1993，361，： | 1 |
| 18 | Effect of light cycles(night/day)on CO2 fixation and biomass production by microalgae in photobioreactors显示文摘 | Eduardo J L Carlos H G S Lucy M C F L | | 0，，01： | 1 |
| 19 | Precision laser automatic tracking system显示文摘 | Peters C J McGann E J | 1966 | Appl Opt1966，5，： | 1 |
| 20 | Clinical significance of health status assessment measures in head and neck cancer: what do quality-of-life scores means?显示文摘 | Gerry F Funk M Lucy H | 2004 | American Medical Association2004，130，7： | 1 |
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