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| 1 | Characteristics of Proinflammatory Cytokines and Chemokines in Airways of Asthmatics: Relationships with Disease Severity and Infiltration of Inflammatory Cells显示文摘 | Ting Yang Yan Li Zhe Lyu Kewu Huang Chris J Corrigan Sun Ying Wei Wang Chen Wang | 2017 | Chinese Medical Journal2017，，17： | 12 |
| 2 | A Taxonomic Re-Assessment of the Novispathodus waageni Group and Its Role in Defining the Base of the Olenekian (Lower Triassic)显示文摘Lower Triassic conodont biostratigraphy has been well studied around the world in the past decades, but the Induan-Olenekian boundary(IOB) remains undecided. The Novispathodus waageni group has been taxonomically re-assessed based on abundant new materials from the Jianshi and Chaohu sections, South China. New study shows that Nv. waageni typically possesses:(1) an approximately equi-dimentional P1 blade element,(2) an accurate upper profile with denticle height descending in both directions,(3) a denticulated posterior edge(lower denticles posterior of the highest denticle), and(4) a round basal cavity outline. Of the three proposed subspecies of the waageni species, both Nv. waageni waageni(Sweet, 1970) and Nv. w. eowaageni(Zhao and Orchard, 2005) are valid, and the former differs clearly from Nv. w. eowaageni in having(1) a slightly higher length/height ratio(holotype=1.30 : 1.23),(2) a thicker blade, sometimes with medial thickening,(3) fewer(broader) denticles per unit length,(4) generally recurved denticles, not straight and upright,(5) highest denticles closer to posterior,(6) common differentiation of a posterior cusp, and(7) more sinuous basal profile, with increased posterior upturning. A third subspecies illustrated as Nv. waageni n. subsp. A sensu Goudemand, 2014 is not conspecific with older individuals of Nv. w. eowaageni, and also cannot be assigned to the Nv. waageni group. Abundant new materials demonstrate a clear ontogenic process for Nv. w. eowaageni, indicating that Nv. w. eowaageni occurring in the Induan-Olenekian boundary(IOB) succession is rather stable. Small, earlier individuals(i.e., those from Bed 225 in Jianshi) are referred to as Nv. w. eowaageni Morphotype A, and are thought to have likely evolved from Ns. dieneri Morphotype 3, and to be the precursor of mature elements of Nv. w. eowaageni. The first appearance datum of Nv. w. eowaageni therefore is an ideal mark defining the IOB. | Zhengyi Lyu Michael J Orchard Zhong-Qiang Chen Laishi Zhao Lei Zhang Xiumei Zhang | 2018 | Journal of Earth Science2018，29，4： | 2 |
| 3 | Phoenixin: a novel brain-gut-skin peptide with multiple bioactivity显示文摘在这简短评论,我们相对小肽 ligand 的发现总结当前的 fndings, phoenixin (PNX ) 。用一条生物信息的途径,分别地,包含 14 和 20 氨基酸的二新奇的肽 PNX-14 和 PNX-20 包括大脑,心,肺和胃从多样的纸巾被孤立。集体 spectrometry 分析识别了相应于 PNX-14 和 PNX-20 的一座主要、次要的山峰,在针的绳索提取的老鼠或老鼠。与兔子 polyclonal 抗血清的使用, phoenixin immunoreactivity (irPNX ) 包括几 hypothalamic subnuclei 和迷走神经的背面的马达原子核在啮齿类动物大脑的分离区域被检测。另外, irPNX 包括背面的根中心,有节的中心和三叉的中心在感觉中心房间的一张人口,并且在浓密地散布到背面的角,独居的道的原子核和针的三叉的道的表面的层的房间过程被检测。irPNX 房间过程也在皮肤和 myenteric 丛被检测,建议一个大脑勇气或大脑皮连接。PNX-14 皮下地注射了到老鼠的颈的项的药理学研究表演挑起了重复的抓一回与 hindpaws 指导了到颈的背的剂量依赖者。我们的结果建议肽 PNX-14 或 PNX-20,可以用作内长的信号分子 transducing 痒感觉之一。另外,从另外的实验室的结果证明外长的 PNX 可以影响象记忆形成,消沉,复制,食物吸入和象 anxiolytic 一样行为那样的很多多样的行为。 | Rong-Ming LYU Alan COWAN Ying ZHANG Yi-Hung CHEN Siok L DUN Jaw-Kang CHANG Nae J DUN Jin Jun LUO | 2018 | Acta Pharmacologica Sinica2018，39，5： | 2 |
| 4 | Cisplatin ototoxicity involves cytokines and STAT6 signaling network显示文摘我们此处调查了在支持 inflammatory cytokines 和 cisplatin ototoxicity 的生产表明串联的 STAT 的角色。cisplatin 注射引起的一个重要听觉缺陷在 Balb/c 被观察(野类型, WT ) 并且 STAT4 −/−, 然而并非在 STAT6 −/− 老鼠。而且,蛋白质的表示层次和支持 inflammatory cytokines 的 mRNA,包括 TNF-α, IL-1β,并且 IL-6,显著地在 WT 和 STAT4 −/−, 然而并非 STAT6 −/− 老鼠的浆液和蜗被增加。Organotypic 文化表明 stereocilia 捆的形状和在从 STAT6 −/− 鼠标的 Corti 的机关的感觉毛细胞层的数组在有 cisplatin 的处理以后是未经触动的,而那些高度在处理以后从 WT 和 STAT4 −/− 鼠标被弄歪并且弄乱。Cisplatin 在 HEI-OC1 听觉的房间导致了 STAT6 的 phosphorylation,并且由显著地保护的 STAT6 特定的 siRNA 的 STAT6 击倒从导致 cisplatin 的房间死亡的 HEI-OC1 听觉的房间和禁止的支持 inflammatory cytokine 生产。我们进一步证明 cisplatin 导致的 IL-4 和 IL-13 与 IL-4 受体 alpha 和 IL-13Rα 由绑定调制了 STAT6 的 phosphorylation; 1。这些调查结果建议发信号的 STAT6 在调停 cisplatin 的支持 inflammatory cytokine 生产和 ototoxicity 起一个枢轴的作用。 | Hyung-Jin Kim Gi-Su Oh Jeong-Han Lee Ah-Ra Lyu Hye-Min Ji Sang-Heon Lee Jeho Song Sung-Joo Park Yong-Ouk You Jeong-Dug Sul Channy Park Sang-Young Chung Sung-Kyun Moon David J Lim Hong-Seob So Raekil Park | 2011 | Cell Research2011，21，6： | 2 |
| 5 | Effect of Lung Squamous Cell Carcinoma Tumor Microenvironment on the CD105(+)Endothelial Cell Proteome显示文摘 | Zhuo H Lyu Z Su J et a1 | 2014 | J Proteome Res2014，13，11： | 1 |
| 6 | Field emission from well-aligned zinc oxide nanowires grown at low temperature显示文摘 | LEE C J LEE T J LYU S C | 2002 | Appl Phy Lett2002，81，18： | 1 |
| 7 | 显示文摘 | Lee C J Lyu T J | 2002 | Applied Physics Letters2002，81，： | 1 |
| 8 | A comprehensive method for multilingual video text detection,localization,and extraction显示文摘 | Lyu M R Song J Q Cai M | 2005 | IEEE Transactions on Circuits and Systems for Video Technology2005，15，2： | 1 |
| 9 | Chnical role of bone marrow angiogenesis in childhood acute lymphocytic leukemia显示文摘 | Lyu C J Rha S Y Won S C | 2007 | Yonsei Med J2007，48，2： | 1 |
| 10 | Study on positioning accuracy of nut/shaft air cooling ball screw for high- precision feed drive显示文摘 | Xu Z Z Liu X J Lyu S K | 2014 | International Journal of Precision Engineering and Manufacturing2014，15，1： | 1 |
| 11 | Topoisomerase Ilbeta mediated DNA double-strand breaks: implications indoxorubicin cardiotoxicity and prevention by dexmzoxane显示文摘 | Lyu Y L Kerrigan J E Lin C P | 2007 | Cancer Res2007，67，18： | 1 |
| 12 | Effects of CaF2 and CaCI2 addition on the formation of llCaO ~ 7A1203 ~ CaS solid solution in the CaO-A1203 slag显示文摘 | Lyu N N Yu J K Su C | 2013 | Metalurgia International2013，6，： | 1 |
| 13 | Ectopic expression of axin blocks neuronal differentiation of embryonic carcinoma P19 cells显示文摘 | Lyu J Costantini F Jho EH | 2003 | J Biol Chem2003，278，13： | 1 |
| 14 | A taxonomic note on Sclerodermas harmandi, ectoparasite of stem aad wood boring insect larvae (Hymenoptera Chrysidoidea-Bethylidae) in South Korea显示文摘 | Lim J O Lyu D P Choi G S | 2006 | Journal Asia-Pacific Entomology2006，9，： | 1 |
| 15 | 查看详情显示文摘 | Lee C J Lee T J Lyu S C | | 0，，： | 1 |
| 16 | Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma显示文摘 | Lyu T Jia N Wang J | 2013 | Epigenetics2013，8，12： | 1 |
| 17 | Nafion sta- bilized magnetic nanoparticles (Fe3O4) for 2+ (bpy= bipyridine) electrogenerated chemi- luminescence sensor显示文摘 | KIM D J LYU Y K CHOI H N | 2005 | Chem Comm2005，23，： | 1 |
| 18 | Wnt-Ta up-regulates matrix metalloproteinase-12 ex- pression and promotes cell proliferation in corneal epithelial ceils dur- ing wound healing 显示文摘 | Lyu J Joo C K | 2005 | J Biol Chem2005，280，21： | 1 |
| 19 | Influence of filler and cure systems on thermal aging resistance of natural rubber vulcanizates under strained condition 显示文摘 | Choi Sung-Seen Jose J Lyu Min-Young | 2010 | Journal of Applied Polymer Science2010，118，5： | 1 |
| 20 | Differentiation of small hepatic hemangioma from small hepatocellular carcinoma: recently introduced spectral CT method 显示文摘 | Lyu P Lin XZ Li J | 2011 | Radiology2011，259，3： | 1 |
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