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| 1 | Rates and risk factors for suicidal ideation,suicide attempts and suicide deaths in persons with HIV:a systematic review and meta-analysis显示文摘Background People living with HIV/AIDS(PLWHA)must contend with a significant burden of disease.However,current studies of this demographic have yielded wide variations in the incidence of suicidality(defined as suicidal ideation,suicide attempt and suicide deaths).Aims This systematic review and meta-analysis aimed to assess the lifetime incidence and prevalence of suicidality in PLWHA.Methods Publications were identified from PubMed(MEDLINE),SCOPUS,OVID(MEDLINE),Joanna Briggs Institute EBP and Cochrane Library databases(from inception to before 1 February 2020).The search strategy included a combination of Medical Subject Headings associated with suicide and HIV.Researchers independently screened records,extracted outcome measures and assessed study quality.Data were pooled using a random-effects model.Subgroup and meta-regression analyses were conducted to explore the associated risk factors and to identify the sources of heterogeneity.Main outcomes were lifetime incidence of suicide completion and lifetime incidence and prevalence of suicidal ideation and suicide attempt.Results A total of 185199 PLWHA were identified from 40 studies(12 cohorts,27 cross-sectional and 1 nested case-control).The overall incidence of suicide completion in PLWHA was 10.2/1000 persons(95%CI:4.5 to 23.1),translating to 100-fold higher suicide deaths than the global general population rate of 0.11/1000 persons.The lifetime prevalence of suicide attempts was 158.3/1000 persons(95%CI:106.9 to 228.2)and of suicidal ideation was 228.3/1000 persons(95%CI:150.8 to 330.1).Meta-regression revealed that for every 10-percentage point increase in the proportion of people living with HIV with advanced disease(AIDS),the risk of suicide completion increased by 34 per 1000 persons.The quality of evidence by Grading of Recommendations,Assessment,Development and Evaluations for the suicide deaths was graded as‘moderate’quality.Conclusions The risk of suicide death is 100-fold higher in people living with HIV than in the general population.Lifetime incidence of suicidal ideation and attempts are substantially high.Suicide risk assessments should be a priority in PLWHA,especially for those with more advanced disease. | Matt Pelton Matt Ciarletta Holly Wisnousky Nicholas Lazzara Monica Manglani Djibril M Ba Vernon M Chinchillli Ping Du Anna E Ssentongo Paddy Ssentongo | 2021 | General Psychiatry2021，34，2： | 3 |
| 2 | Sodium - calcium ex- change initated by the Ca2+ transient:an arrhythmia trigger within pulmonary veins显示文摘 | Patterson E Lazzara R Szabo B | 2006 | J Am Coll Cardiol2006，47，6： | 1 |
| 3 | Foom first calss to third class:Recent upheaval in antiarrhythmic therapy-lessons from clinical trials显示文摘 | | 1996 | Am J Cardiol1996，78，4： | 1 |
| 4 | Spectral absorption and fluorescence excitation properties of phytoplanktonic populations at a mesotrophic and an oligotrophic site in the tropical North Atlantic (EUMELI program)显示文摘 | LAZZARA L BRICAUD A CLAUSTRE H | 1996 | Deep-Sea Res (I)1996，43，： | 1 |
| 5 | Platform switching: a new concept in im- plant dentistry for controlling postrestorative crestal bone lev- els 显示文摘 | Lazzara R J Porter SS | 2006 | Int J Periodontics Restorative Dent2006，26，： | 1 |
| 6 | Autonomicalty induced conversion of pulmonary vein focal firing into atrial fibrillation显示文摘 | Scherlag B J Yamanashi W Lazzara R | 2005 | J Am Coll Cardiol2005，45，11： | 1 |
| 7 | The benefit of cardiac resynchronization therapy and QRS duration:a meta-analysis显示文摘 | Stavrakis S Lazzara R Thadani U | 2012 | J Cardiovasc Electrophysiol2012，23，： | 1 |
| 8 | Platform switching:a new concept in implant dentistry for controlling postrestorative crestal bone levels显示文摘 | Lazzara RJ Porter SS | 2006 | Int J Periodontics Restorative Dent2006，26，1： | 1 |
| 9 | Immediate occlusal loading of Os-seotite implants in mandibular edentulous patients:a pro-spective observational report with 18-month data显示文摘 | Dragoo C J Lazzara R J | 2006 | JProsthodont2006，15，： | 1 |
| 10 | EGF augments TGFI3 - induced epithelial -mesenchymal transition by promoting SHP2 binding to GABI 显示文摘 | Buonato JM Lan IS Lazzara MJ | 2015 | J Cell Sci2015，128，21： | 1 |
| 11 | Laparoscopic cholecystectomy in cirrhotic patients显示文摘 | Cucinotta E Lazzara S Nelita G | 2003 | Surg Endo2003，17，12： | 1 |
| 12 | Radiology- pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma显示文摘 | Lazzara BM Scalcione LR Garnet DJ | 2012 | Clin Imaging2012，36，1： | 1 |
| 13 | Use of a compressive leverage apparatus versus manual pressure in achieving hemostasis after invasive procedure 显示文摘 | Almany SL Cragg DR Lazzara S | 1993 | J Am Coll Cardiol1993，21，： | 1 |
| 14 | Rapid inward current in ischemically-injured subepicardial myocytes bordering myocardial infarction显示文摘 | Patterson E Scherlag BJ Lazzara R | 1993 | J Cardiovasc Electrophsiol1993，4，： | 1 |
| 15 | Immediate implant placement into extraction sites:Surgical and restorative advantages显示文摘 | Lazzara RJ | 1989 | Int J Pefiodontics Restorative Dent1989，9，5： | 1 |
| 16 | Platform switching:a new concept in implant dentistry for controlling postrestorative crestal bone levels显示文摘 | Lazzara RJ Porter SS | 2006 | Int J Periodontics Restorative Dent2006，26，1： | 1 |
| 17 | The effects of ventilation and preburn time on water mist extinguishing of diesel fuel pool fires 显示文摘 | Yuan L M Lazzara C P | 2004 | Journal of Fire Science2004，22，5： | 1 |
| 18 | Functional transverse interconnections within the his bundle and the bundle branches显示文摘 | LAZZARA R K SAMET P | 1973 | CircRes1973，32，： | 1 |
| 19 | Heterogeneous regional endeoardial repolarization is as- sociated with increased risk for ischemia - dependent ventricular fi- brillation after myocardial infarction 显示文摘 | SwanniVIH Nakagawa H Vanoli E Lazzara R Schwartz P J Ad- amsonPB | 2003 | J Cardiovasc Electro- physiol2003，14，8： | 1 |
| 20 | The benefit of cardiac re- synchronization therapy and QRS duration: a meta-analysis 显示文摘 | Stavrakis S Lazzara R Thadani U | 2012 | J Cardiovasc Electrophysiol2012，23，2： | 1 |
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