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    题名 作者 年代 出处 被引量
1Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F 2005中国神经肿瘤杂志2005,3,3:53
2人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M 2017中华高血压杂志2017,25,6:9
3Lack of Efficacy of Bevacizumab Plus Irinotecan in Children with Recurrent Malignant Glioma and Diffuse Brainstem Glioma:A Pediatric Brain Tumor Consortium Study显示文摘PURPOSE:A phase Ⅱ study of bevacizumab(BVZ) plus irinotecan(CPT-11) was conducted in children with recurrent malignant glioma(MG) and intrinsic brainstem glioma(BSG).PATIENTS AND METHODS:Eligible patients received two doses of BVZGururangan S Chi SN Young Poussaint T Onar-Thomas A Gilbertson RJ Vajapeyam S Friedman HS Packer RJ Rood BN Boyett JM Kun LE 2010中国神经肿瘤杂志2010,8,2:7
4脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊 2018神经损伤与功能重建2018,13,4:4
5Radiographic and Clinical Comparisons of Distal Tibia Shaft Fractures (4 to 11 cm Proximal to the Plafond): Plating Versus Intramedullary Nailing显示文摘Heather A Vallier T Toan Le Asheesh Bedi 2008Journal of Orthopaedic Trauma2008,,5:2
6Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma显示文摘Le Q T Tate D Koong A 2003Int J Radiat Oncol Biol Phys2003,56,4:2
7ZSM-5 zeolite with enhanced acidic properties显示文摘Le Van Mao R Le T S Fairbain M Muntasar A Xiao S Denes G 0,,:2
8A hybrid intelligent system for predicting bank holding structures显示文摘R R Hashemi L A Le Blanc C T Rucks 1998European Journal of Operational Research1998,109,:1
9Spatial partitioning of the soil water resource between grass and shrub com- ponents in a West African humid savanna显示文摘Le Roux X Bariac T Mariotti A 1995Oecolo- gia1995,104,2:1
10Characterization of Ba- cillus pmbiotics available for human use显示文摘Due le H Hong H A Barbosa T M 2004Appl Environ Micro- biol2004,70,4:1
11Association of the hoGG1 Ser326Cys polymorphism with lung cancer risk显示文摘Le Marchand L Donlon T Lum-Jones A 2002Cancer Epidemiol Biomarkers Prev2002,11,4:1
12Long-term results of the International Adjuvant Lung Cancer Trial (IALT) evaluating adjuvant Cisplatin-based chemotherapy in resected non-small-cell lung cancer (NSCLC) 显示文摘Le Chevalier T Dunant A Arriagada R 2010J Clin Oncol2010,28,1:1
13Relating forest biomass to SAR data显示文摘LE T T BEAUDOIN A RIOM J 1992IEEE Transactions on Geoscience and Remote Sensing1992,30,2:1
14Subjective reactions to intervention with artificial interferences in subjects with and without a history of temporomandibular disorders显示文摘Le Bell Y Niemi PM J(a)ms(a) T 2006Acta Odontol Scand2006,64,1:1
15Development of thermo- stable Candidaantarctica lipase B through novel in silico design of disulfidebridge显示文摘LE Q A T JOO J C YOO Y J 2012Biotechnology and Bioengineering2012,109,4:1
16Hardened properties of high- performance printing concrete 显示文摘T T Le S A Austin S Lira 2012Cement and Concrete Research2012,,42:1
17Pre- dicting effects of cations on copper toxicity to lettuce (Lactuca sativa) by the biotic ligand model 显示文摘Le T T Y Peijnenburg W J G M Hendriks A J 2012Environ- mental Toxicology and Chemistry2012,31,2:1
18High resolution EEG: 124-channel recording, spatial deblurring and MRI integration methods 显示文摘 LE J MARTIN N K BRICKET T P 1994Electroencephalography and Clinical Neurophysiology1994,90,:1
19Space-Time-Frequency Code implementation in MB-OFDM UWB communications: Design criteria and performance显示文摘LE C T MERTINS A 2009Wireless Commu- nications IEEE Transactions on2009,8,2:1
20Irrigated agriculture and wildllfe conservation: Conflict on a global scale显示文摘Le mly A D Kingsford R T Thompson J R 2000Environ- ment Management2000,25,:1
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