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| 1 | 地理信息系统技术在伤寒发热监测中应用显示文摘目的运用地理信息系统(GIS)技术,了解各居民点发热流行率和评价以医疗机构为哨点的伤寒发热监测系统的敏感性。方法收集医学人口普查数据、疾病监测系统信息数据、现场采集居民居住点全球卫星定位数据等资料,建立GIS系统和以人口为基数的发热监测系统;对所有发热就诊病人进行身份和居住地址确认,并制作各居民点年发热就诊率GIS分布图。结果共采集3776个居民居住的全球定位系统(GPS)定位点,人群发热就诊率为1.11‰,发热就诊人次占总门诊人次的16.3%,监测区内的发热就诊病人占所有发热就诊病人的83.5%。在3种类型的医疗机构中,门诊量以个体门诊类最多,但其发热就诊人次占总门诊人次的比率最低(12.6%)。监测区内发热1d或以上的病人地址和身份(ADDRESS-ID)确认率达到95%。根据居民点年发热就诊率GIS分布图,发热就诊率最高的居民点达到17.81‰,最低为0;发热就诊率高的居民点多集中在城市。结论利用GIS技术可直观准确的了解疾病流行率的分布,可迅速直观的寻找出监测系统中的薄弱环节和推断出可能存在的问题。 | 杨进 董柏青 张杰 廖和壮 梁大斌 吴兴华 司国爱 杨宏徽 Jin Kyung Park R Leon Ochiai Camilo J Acosta Moharmmad Ali John D Clemens | 2007 | 中国公共卫生2007，23，9： | 8 |
| 2 | Standard forward-viewing colonoscopy versus full-spectrum endoscopy: an international, multicentre, randomised, tandem colonoscopy trial显示文摘 | Ian M Gralnek Peter D Siersema Zamir Halpern Ori Segol Alaa Melhem Alain Suissa Erwin Santo Alan Sloyer Jay Fenster Leon M G Moons Vincent K Dik Ralph B D’Agostino Douglas K Rex | 2014 | Lancet Oncology2014，，3： | 6 |
| 3 | Endoscopic innovations to increase the adenoma detection rate during colonoscopy显示文摘Up to a quarter of polyps and adenomas are missed during colonoscopy due to poor visualization behind folds and the inner curves of flexures,and the presence of flat lesions that are difficult to detect.These numbers may however be conservative because they mainly come from back-to-back studies performed with standard colonoscopes,which are unable to visualize the entire mucosal surface.In the past several years,new endoscopic techniques have been introduced to improve the detection of polyps and adenomas.The introduction of high definition colonoscopes and visual image enhancement technologies have been suggested to lead to better recognition of flat and small lesions,but the absolute increase in diagnostic yield seems limited.Cap assisted colonoscopy and water-exchange colonoscopy are methods to facilitate cecal intubation and increase patients comfort,but show only a marginal or no benefit on polyp and adenoma detection.Retroflexion is routinely used in the rectum for the inspection of the dentate line,but withdrawal in retroflexion in the colon is in general not recommended due to the risk of perforation.In contrast,colonoscopy with the Third-Eye Retroscope?may result in considerable lower miss rates compared to standard colonoscopy,but this technique is not practical in case of polypectomy and is more time consuming.The recently introduced Full Spectrum Endoscopy?colonoscopes maintains the technical capabilities of standard colonoscopes and provides a much wider view of 330 degrees compared to the 170 degrees with standard colonoscopes.Remarkable lower adenoma miss rates with this new technique were recently demonstrated in the first randomized study.Nonetheless,more studies are required to determine the exact additional diagnostic yield in clinical practice.Optimizing the efficacy of colorectal cancer screening and surveillance requires high definition colonoscopes with improved virtual chromoendoscopy technology that visualize the whole colon mucosa while maintaining optimal washing,suction and therapeutic capabilities,and keeping the procedural time as low and patient discomfort as optimal as possible. | Vincent K Dik Leon MG Moons Peter D Siersema | 2014 | World Journal of Gastroenterology2014，20，9： | 6 |
| 4 | Intussusception in adults: institutional review 1 1 No competing interests declared.显示文摘 | Leon K Eisen John D Cunningham Arthur H Aufses | 1999 | Journal of the American College of Surgeons1999，，4： | 3 |
| 5 | Immunohistochemical analysis of the activation of NF-kappaB and expression of associated cytokines and adhesion molecules in human models of allergic inflammation显示文摘 | Wilson SJ Leone BA Anderson D | 1999 | J Pathol1999，189，： | 3 |
| 6 | Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico显示文摘 | Perez-Padilla R de la Rosa Zamboni D Ponce de Leon S | 2009 | N Engl J Med2009，361，7： | 1 |
| 7 | Pneumonia and respiratory failure from swine-origin influenza A ( H1N1 ) in Mexico显示文摘 | Perez-Padilla R De la Rosa-Zamboni D Ponice de Leon S | 2009 | N Engl J Med2009，361，7： | 1 |
| 8 | Carbon monoxide intoxication: An updated review 显示文摘 | Leon D P Rossitza I C | 2007 | Journal of the Neurological Sciences2007，262，： | 1 |
| 9 | Robustness measures and robust scheduling for job shops 显示文摘 | V J Leon S D Wu H Storer | 1993 | IIE Transactions1993，26，5： | 1 |
| 10 | Free DNA in the serum of cancer patients and the effect of therapy显示文摘 | Leon S A Shapiro B Sklaroff D M | 1977 | Cancer Res1977，37，： | 1 |
| 11 | Immunohistochemical analysis of the activation of NF-kappa B and expression of associated cytokines and adhesion molecules in human models of allergic inflammation显示文摘 | Wilson SJ Leone BA Anderson D | 1999 | J Pathol1999，189，2： | 1 |
| 12 | Psychological Antecedents of Student Procrastination显示文摘 | Gery Beswick Esther D Rothblum & Leon Mann | 1988 | Australian Psychologist1988，23，2： | 1 |
| 13 | Free DNA in the serum of cancer patients and the effect of therapy显示文摘 | LEON S A SHAPIRO B SKLAROFF D M | 1997 | Cancer Res1997，37，3： | 1 |
| 14 | Chief Executive Officers and Voluntary Environmental Performance : Costa Rica' s Certification for Sustainable Tourism显示文摘 | Rivera J Leon P D | 2005 | Source: Policy Sciences2005，38，23： | 1 |
| 15 | Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic bcl-2-family proteins显示文摘 | M Leone D Zhai S Sareth et d | 2003 | Cancer Research2003，63，： | 1 |
| 16 | Cancer prevention by tea polyphenols is linked to the irdirect inhibition of a tiapoptotic Bcl-2-family protein显示文摘 | Leone M Zhai D Sareth S | 2003 | Cancer Res2003，63，： | 1 |
| 17 | Unbraneed frames with semi- rigid composite connections显示文摘 | AMMERMAN D J LEON R | 1990 | Engineering Journal AISC1990，27，1： | 1 |
| 18 | Unbranced frames with semirigid composite connections 显示文摘 | AMMERMAN D J LEON R | 1990 | Engineering Journal AISC1990，27，1： | 1 |
| 19 | Time course of cytokine,corticosterone,and tissue injury responses in mice during heat strain recovery显示文摘 | LEON L R BLAHA M D DUBOSE D A | 2006 | J Appl Physiol2006，100，4： | 1 |
| 20 | Pneumonia and respiratory failure from swine-origin influenza A (H1N1)in mexico显示文摘 | Peres-Padilla R de la Rosa-Zamboni D Ponce de Leon S | 2009 | N Engl J Med2009，361，7： | 1 |
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