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| 1 | Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease:An observation on non-absorbable antibiotics显示文摘AIM: To estimate the prevalence of small intestine bacterial overgrowth (SIBO) among patients with an earlier diagnosis of irritable bowel disease (IBS) in our geographical area, and to collect information on the use of locally acting non-absorbable antibiotics in the management of SIBO. METHODS: A non-interventional study was conducted in 73 consecutive patients with a symptom-based diagnosis.. RESULTS: When the patients underwent a 'breath test', 33 (45.2%) showed the presence of a SIBO. After treatment with rifaximin 1200 mg/d for seven days in 32 patients, 19 (59.4%) showed a negative 'breath test' one week later as well as a significant reduction of symptoms, thus confirming the relationship between SIBO and many of the symptoms claimed by patients. In the other 13 patients, 'breath test' remained positive, and a further cycle of treatment with ciprofloxacin 500 mg/d was given for 7 additional days, resulting in a negative 'breath test' in one patient only. CONCLUSION: (1) about half of the patients with a symptomatic diagnosis of IBS have actually SIBO, which is responsible for most of the symptoms attributed to IBS; (2) only a 'breath test' with lactulose (or with glucose in subjects with an intolerance to lactose) can provide a differential diagnosis between IBS and SIBO, with almost identical symptoms; and (3) the use of non-absorbable antibiotics may be useful to reduce the degree of SIBO and related symptoms; it must be accompanied, however, by the correction of the wrong alimentary habits underlying SIBO. | I Esposito A de Leone G Di Gregorio S Giaquinto L de Magistris A Ferrieri G Riegler | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 2 | Incidence and susceptibility to therapy- related myeloid neoplasms 显示文摘 | Leone G Fianchi L Pagano L | 2010 | Chem Biol Interact2010，184，12： | 1 |
| 3 | The age of multilevel converters arrives显示文摘 | L G Franquelo J Rodriguez J I Leon S Kouro R Portillo and M A M Prats | | 0，，02： | 1 |
| 4 | The dependency of microstructure and properties of nanostructured coatings on plasma spray conditions 显示文摘 | Leon L Shaw Daniel G | 2000 | Surface and Coatings Technology2000，130，： | 1 |
| 5 | Human challenges in polar and space enviroument显示文摘 | SANDAL G M LEON G R PALINKAS L A | 2006 | Reviews in Environmental Science and Bio/technology2006，，5： | 1 |
| 6 | Laparoscopic management of small bowel obstruction: indications and outcome显示文摘 | Leon E L Metzger A Tsiotos G G | 1998 | J Gastrointest Surg1998，2，2： | 1 |
| 7 | Power-electronic systems for the grid integration of renewable energy sources: A survey 显示文摘 | CARRASCO J M FRANQUELO L G BIALASIEWICZ J T GALVAN E GUISADO R C P PRATS M A M LEON J I MORENO N | 2006 | IEEE Transactions on Industrial Electronics2006，53，4： | 1 |
| 8 | Therapeutic antibody targeting of indi- vidual Notch receptors显示文摘 | Wu Y Cain-Hom C Choy L Hagenbeek T J de Leon G P Chen Y | 2010 | Nature2010，464，： | 1 |
| 9 | The effect of tallow concentration on the cold rolling of steel strips显示文摘 | Leon B N John G L | 2003 | Journal of Materials Processing Technology2003，142，： | 1 |
| 10 | Spontaneous erythroid colony formation as the clue to an underlying myeloproliferative disorder in patients with Budd-Chiari syndrome or portal vein thrombosis显示文摘 | DeStefano V Teofili L Leone G | 1997 | Semin Thromb Hemost1997，23，： | 1 |
| 11 | Therapy-related leukemia and myIodysplasia : susceptibility and incidence 显示文摘 | Leone G Pagano L Ben-yehuda D | 2007 | Haematologica2007，92，10： | 1 |
| 12 | Gemcitabine,cisplatin and vinorelbine as inducation chemotherapy followed by radical therapy in stage Ⅲ non-small cell lung cancer:a multicenter study of Galician-lung-cancer-group显示文摘 | Leon L Cueva-Banuelos JF Huidobro G | 2003 | Lung Cancer2003，40，2： | 1 |
| 13 | Validation of an agricultural non-point source model in watershed in Southern Ontario显示文摘 | Leon L F Booty W G | 2004 | Agricultural Water Management2004，65，： | 1 |
| 14 | The age of multilevel converters arrives显示文摘 | Franquelo L G Rodriguez J Leon J I | 2008 | IEEE Ind Electron Magazine2008，2，2： | 1 |
| 15 | Incidence and susceptibility to therapy-related myeloid neoplasms 显示文摘 | Leone G Fianchi L Pagano L | 2010 | Chem Biol Interact2010，184，12： | 1 |
| 16 | The age of multi-level converters arrives显示文摘 | Franquelo L G Rodriguez J Leon J I | 2008 | IEEE Industrial Electronics Magazine2008，2，2： | 1 |
| 17 | Characterization and complete nucleotide sequence of Strawberry mottle virus: A tentative member of a new family of bipartite plant picoma - like viruses显示文摘 | Thompson J R Leone G Lindner J L | 2002 | Journal of General Virology2002，83，： | 1 |
| 18 | Detection of apple juice adulteration using near-infrared transflectance spectroscopy显示文摘 | Leon L Kelly J D Downey G | 2005 | Appl Spectrosc2005，59，5： | 1 |
| 19 | The age of multilevel converter arrives显示文摘 | FRANQUELO L G RODRIGUEZ J LEON J I | 2008 | IEEE Trans on Industrial Electronics Magazine2008，2，2： | 1 |
| 20 | Collaborative role of E2F transcriptional activity and G1 cyclin dependent kinase activity in the induction of S phase显示文摘 | Leone G DeGrcgori J Jakoi L | 1999 | Proc Natl Acad Sci USA1999，96，12： | 1 |
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