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183篇 您的检索式：作者名="Letterio"

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	题名	作者	年代	出处	被引量
1	Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease: a review显示文摘镰刀房间疾病(SCD ) 是在的血红素的继承混乱反常血红素 S polymerizes 当除去时。血红素 S 的这聚合不仅导致溶血和 vasoocclusion 而且猛抛发炎,氧化压力和长期的机关机能障碍。当在这些 pathophysiological 的重要中介处理并且因此是为治疗学的干预的一个重要目标,氧化应力逐渐地被认出。原子 erythroid derived-2 联系了的抄写因素(Nrf2 ) 因素 2 控制抗氧化剂酶的表达式并且作为其函数能与治疗学的目的被利用的蛋白质新兴。这篇评论文章集中于 triterpenoids 为作为一条途径在 SCD 减少氧化应力阻止与这疾病联系的机关机能障碍激活 Nrf2,和他们的潜力。在 SCD 的临床的上下文的氧化应力的简短概述被贡献氧化应力的几 pathophysiological 机制的讨论伴随。最后,这些机制当时与在是当前或在评估下面利用的任何一个的 SCD 的当前的管理策略有关。文章在各种各样的治疗学的干预的潜力上与一个观点得出结论减少与 SCD 联系的氧化应力和病态。	Amma Owusu-Ansah Sung Hee Choi Agne Petrosiute John J. Letterio Alex Yee-Chen Huang	2015	Frontiers of Medicine2015，9，1：	2
2	TGF-betal maintains suppressor function and Foxp3 expression in CD4^+ CD25^+ regulatory T cells显示文摘	Marie J C Letterio J J Gavin M Rudensky A Y	2005	J Exp Med2005，201，：	1
3	TGF-beta knockout and dominant-negative receptor transgenic mice 显示文摘	Letterio JJ Bottinger EP	1998	Miner Electrolyte Metab1998，24，23：	1
4	TGF-bl maintains suppressor function and Foxp3 expression in CD4^ + CD25 ^+ regulatory T cells 显示文摘	Marie JC Letterio JJ Gavin M	2005	J Exp Med2005，201，：	1
5	TGF-betal maintains suppressor function and Foxp3 expression in CD4^+CD25^+ regulatory T cells 显示文摘	Marie JC Letterio JJ Gavin M	2005	J Exp Med2005，201，7：	1
6	Transforming growth factor-beta signaling in normal and malignant hemato-poiesis显示文摘	Kim SJ Letterio J	2003	Leukemia2003，17，9：	1
7	TGF-beta knockout and dominant-negative receptor transgenic mice显示文摘	Letterio JJ Bottinger EP	1998	Miner Electrolyte Metab1998，24，：	1
8	The Smad3 protein is involved in TGFβ1 inhibition of class Ⅱ transactivator and class Ⅱ MHC expression 显示文摘	Dong Y Tang 1 Letterio J J	2001	J lmmunol2001，167，1：	1
9	Transforming growth factor-beta signaling in normal and malignant hematopoiesis显示文摘	Kim SJ Letterio J	2003	Leukemia2003，17，9：	1
10	TGF-betal maintains suppressor function and Foxp3 expression in CD4^+CD25^+ regulatory T cells 显示文摘	Marie JC Letterio JJ Gavin M	2005	J Exp Med2005，201，7：	1
11	Regulation of immune responses by trasforming growth factor-β 显示文摘	Roberts AB	1998	Annu Rev Immunol1998，16，：	1
12	TGF-beta1 maintains suppressor function and Foxp3 expression in CD4 + CD25 + regulatory T cells显示文摘	Letterio J J Gavin M	2005	J Exp Med2005，201，7：	1
13	TGF-betal maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells显示文摘	Marie JC Letterio JJ Gavin M	2005	J Exp Med2005，201，7：	1
14	TGF-beta: a critical modulator of immune cell function 显示文摘	Letterio J J Roberts A B	1997	Clinical Immunol Immunopathol1997，84，：	1
15	TGF-betal maintains suppressor function and Foxp3 expression in CD4^+CD25^+ regulatory T cells 显示文摘	Marie J C Letterio J J Gavin M	2006	J Exp Med2006，201，7：	1
16	Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to transforming growth factor-β显示文摘	Letterio JJ Lechleider RJ	1999	EMBO J1999，18，5：	1
17	Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T-cell responsiveness to TGF-β 显示文摘	Yang X Letterio J J Lechleider R J	1999	EMBO J1999，18，5：	1
18	TGF-betal maintains suppressor function and Foxp3 expression in CD4 + CD25 +regulatory T cells显示文摘	Marie JC Letterio JJ Gavin M	2005	J Exp Med2005，201，7：	1
19	TGF-β1maintainssuppressor function and Foxp3 expression in CD4+CD25+regulatory T cells显示文摘	Marie J C Letterio J J Gavin M	2005	J Exp Med2005，201，7：	1
20	Role of molecular imaging in the management of patients affected by inflammatory bowel disease:State-of-the-art显示文摘AIM To present the current state-of-the art of molecular imaging in the management of patients affected by inflammatory bowel disease(IBD).METHODS A systematic review of the literature was performed in order to find important original articles on the role of molecular imaging in the management of patients affected by IBD. The search was updated until February 2016 and limited to articles in English.RESULTS Fifty-five original articles were included in this review, highlighting the role of single photon emission tomography and positron emission tomography. CONCLUSION To date, molecular imaging represents a useful tool to detect active disease in IBD. However, the available data need to be validated in prospective multicenter studies on larger patient samples.	Federico Caobelli Laura Evangelista Natale Quartuccio Demetrio Familiari Corinna Altini Angelo Castello Mariapaola Cucinotta Rossella Di Dato Cristina Ferrari Aurora Kokomani Iashar Laghai Riccardo Laudicella Silvia Migliari Federica Orsini Salvatore Antonio Pignata Cristina Popescu Erinda Puta Martina Ricci Silvia Seghezzi Alessandro Sindoni Martina Sollini Letterio Sturiale Anna Svyridenka Vittoria Vergura Pierpaolo Alongi	2016	World Journal of Radiology2016，8，10：	1

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