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| 1 | Role of environmental pollution in irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS),with the prevalence of 10%-20 % of the population has become an emerging problem worldwide. IBS is a functional gastrointestinal(GI) disorder characterized by abdominal pain or discomfort and altered bowel habits. The etiology of IBS contains genetic,psychological,and immunological factors,and has not been fully elucidated; of note,recent studies also point at environmental pollution and its role in the development of functional GI diseases. In this review we focus on several environmental factors,such as bacterial contamination,air pollution,radiation and even stress as potential triggers of IBS. We discuss associated disturbances in homeostasis,such as changes in intestinal microbiome and related pathophysiological mechanisms. Based on the effect of environmental factors on the GI tract,we also propose novel targets in IBS treatment. | Mateusz Marynowski Aleksandra Likońska Hubert Zatorski Jakub Fichna | 2015 | World Journal of Gastroenterology2015，21，40： | 10 |
| 2 | Suction stress characteristic curve for unsaturated soil 显示文摘 | Lu N Likos W J | 2006 | Journal of Geotechnical and Geoen-vironmental Engineering2006，132，2： | 1 |
| 3 | Hysteresis of capillary stress in unsaturated granular soil显示文摘 | LIKOS W J LU N | 2004 | Journal of Engineering Mechanics2004，130，6： | 1 |
| 4 | Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor显示文摘 | Feng Y Zhu L Likos J | 2002 | Biochim Biophys Acta:Proteins and Proteomics2002，1598，12： | 1 |
| 5 | Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor 显示文摘 | Feng Y Likos J J Zhu L | 2002 | Biochim Biophys Acta2002，1598，： | 1 |
| 6 | Novel mutation of the CYP17 gene in two unrelated patients with combined 17 alpha-hydroxylase/17,20 -lyase deficiency : Demonstration of absent enzyme activity by expressing the mutant CYP17 gene and by three-dimensional modeling 显示文摘 | Patocs A Liko I Varga I | 2005 | J Steroid Biochem Mol Biol2005，97，3： | 1 |
| 7 | Hysteresis of capillary stress in unsaturated granular soil显示文摘 | LIKOS W J LU N | 2004 | J Eng Mech2004，130，6： | 1 |
| 8 | Suction stress characteristic curve for unsaturated soil显示文摘 | LU N LIKOS W J | 2006 | Journal of Geotechnical and Geoenvironmental Engineering2006，132，2： | 1 |
| 9 | Suction stress characteristic curve for unsaturated soil显示文摘 | LU N LIKOS W J | 2006 | Journal of Geotechnical and Geoenvironmental Engineering ASCE2006，132，2： | 1 |
| 10 | Pose-scale analysis of bulk volume change from crystalline interlayer swelling in Na^+ -and Ca^2+ -smectite显示文摘 | LIKOS William J LU Ning | 2006 | Clays and Clay Minerals2006，54，4： | 1 |
| 11 | Down-regulation of Weel kinase by a specific subset of microRNA in human sporadic pituitary adenomas显示文摘 | BUTZ H LIKO I CZIRJAK S | 2010 | J Clin Endocrinol Metab2010，95，10： | 1 |
| 12 | Quantification of Grain, Pore, and Fluid Microstructure of Unsaturated Sand from X-Ray Computed Tomography Images 显示文摘 | WILLSON C S LU N LIKOS W J | 2012 | Geotechnical Testing Journal2012，35，6： | 1 |
| 13 | A novel mechanism between typeⅡdiabetes mellitus and procalcitonin gene expression显示文摘 | Patocs A Liko I Varga I | 2005 | FEBS Journal2005，272，1： | 1 |
| 14 | Priming with whole-cell versus aceUular pertussis vaccine 显示文摘 | Liko J Robison SG Cieslak PR | 2013 | N Engl J Med2013，368，6： | 1 |
| 15 | Down-regulation of Weel kinase bya specific subset of microRNA in human sporadic pituitary adenomas 显示文摘 | Butz H Liko L Czirjak S | 2010 | J Clin Endocrinol Metab2010，95，10： | 1 |
| 16 | Suction stress characteristic curve for unsaturated soil显示文摘 | LU N LIKOS W J | 2006 | Journal of Geotechnical andGeoenvironmental Engineering ASCE2006，132，2： | 1 |
| 17 | Suction stress characteristics curve for unsatu- rated soils显示文摘 | Lu N Likos W J | 2006 | Journal of Geotechinical and Geoenvironmental Engineering2006，132，2： | 1 |
| 18 | A tale of two clades:monkeypox viruses显示文摘 | Likos AM Sammons SA Olson VA | 2005 | J Gen Virol2005，86，26： | 1 |
| 19 | Collapse of telechelic star polymers to watermelon structures显示文摘 | LO VERSO F LIKOS C N MAYER C | 2006 | Phys Rev Lett2006，96，18： | 1 |
| 20 | Computer simulation of thermally sensitive telechelic star polymer显示文摘 | LO VERSO F LIKOS C N LWEN H | 2007 | J Chem Phys C2007，111，15： | 1 |
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