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| 1 | Modulation of IL-37 expression by triptolide and triptonide in THP-1 cells显示文摘IL-37 是仅仅最近被识别的反煽动性的 cytokine,并且它高度与煽动性、自体免疫的疾病从病人在纸巾被表示。煽动性的 cytokines 和煽动性的刺激能导致 IL-37 的 upregulation。然而,反煽动性的药是否导致 IL-37 的表示,没被报导。在这个工作,第一次,我们揭开了那主要 bioactive 二个部件, triptolide 和 triptonide,从植物 Tripterygium wilfordii 钩 f。(TwHF ) ,它拥有反煽动性的活动, upregulate IL-37 的表示,和这表情被 ERK1/2 和 p38 MAPK 禁止者压制。总的来说,第一次,我们的研究表明了那反煽动性的活跃部件(triptolide 和 triptonide ) upregulated 经由 ERK1/2 和 p38 MAPK 小径的激活最可能的 IL-37 的表示。 | Lingge He Zhuangyan Liang Fuqian Zhao Lifei Peng Zhangquan Chen | 2015 | Cellular & Molecular Immunology2015，12，4： | 14 |
| 2 | Cooperative spectrum sensing based on stochastic resonance in cognitive radio networks显示文摘A new censoring cooperative spectrum sensing scheme based on stochastic resonance(SR)technique in cognitive radio(CR)network is proposed in this paper.The observations of the cooperative secondary users(SUs)whose statistics fall into the censoring interval are processed by SR system in the proposed scheme.The hard fusion and the soft fusion for the censoring cooperative spectrum sensing scheme are analyzed respectively.Theoretical analyses and simulation results show that the proposed censoring cooperative spectrum sensing scheme has the same detection performance as and lower computational complexity than the method that each cooperative SU performs spectrum sensing using SR-based energy detection,and its detection performance is superior to that of the conventional method that all the cooperative SUs perform spectrum sensing using energy detection in hard fusion.In soft fusion,the proposed censoring cooperative spectrum sensing based on equal gain combination can achieve the optimal sensing performance approximately. | LIN YingPei HE Chen JIANG LingGe HE Di | 2014 | Science China(Information Sciences)2014，57，2： | 8 |
| 3 | Optimal Price-Based Power Control Algorithm with Quality of Service Constraints in Cognitive Radio Networks显示文摘In price-based cognitive radio networks,the Primary user(PU) can allow the Secondary users(SUs) to access by pricing if their interference power is under the Interference power constraint(IPC). The interaction between the PU and the SUs is modeled as a Stackelberg game with the consideration of the Quality of service(Qo S) of the SUs. The revenue maximization problem of PU is expressed as an equivalent convex optimization problem if the minimum Signal-to-interference and noise ratio(SINR) constraints for the SUs are greater than or equal to 0d B. An optimal pricing algorithm is proposed based on this equivalent convex optimization problem. Simulation results show that the proposed pricing algorithm outperforms the non-uniform pricing algorithm in terms of the revenue of the PU, the sum rate of SUs and the number of admitted SUs. | WANG Zhengqiang JIANG Lingge HE Chen | 2015 | Chinese Journal of Electronics2015，24，2： | 4 |
| 4 | LncRNA HOTAIR promotes endometrial fibrosis by activating TGF-β1/Smad pathway显示文摘Homeobox transcript antisense RNA(HOTAIR)is a long non-coding RNA associated with a number of fibrosis-related diseases.The aim of this study was to investigate the specific role of HOTAIR in the development of endometrial fibrosis and to identify the molecular mechanisms underlying this process.Reverse transcription-quantitative polymerase chain reaction(RT-qPCR)was used to determine the expression levels of HOTAIR in samples of intrauterine adhesion(lUA)tissue and in endometrial stromal cells(ESCs)that had been treated with transforming growth factor beta 1(TGF-β1).Additionally,we transfected ESCs with either overexpression plasmid(pcDNA-HOTAIR)or silencing construct(si-HOTAIR)and then treated these cells with TGF-β1.We then performed RTqPCR and western blot analysis,along with cell proliferation and apoptosis assays,to investigate the effects of HOTAIR on the transdifferentiation of ESCs into myofibroblasts.The results showed that the expression levels of HOTAIR were significantly elevated in IUA tissue and in ESCs that had been treated with TGF-β1.The overexpression of HOTAIR had a pro-fibrotic effect on ESCs,while the silencing of HOTAIR exerted an anti-fibrotic effect.Most importantiy,the protein expression levels of p-Smad2 and p-Smad3 were significantly upregulated in TGF-β1.treated ESCs transfected with pcDNA-HOTAIR and were downregulated after transfection with si-HOTAIR constructs.These data indicate that HOTAIR promotes endometrial fibrosis by activating the TGF-β1/Smad signaling pathway,suggesting that the inhibition of HOTAIR may represent a promising therapeutic option for suppressing endometrial fibrosis. | Jianhong Wu Lingge Jin Yudi Zhang Aihong Duan Juhong Liu Ziwen Jiang Liang Huang Jing Chen Zhaohui Liu Dan Lu Yinmei Dai | 2020 | Acta Biochimica et Biophysica Sinica2020，52，12： | 3 |
| 5 | An analytical model for SMAC protocol in multi-hop wireless sensor networks显示文摘Considering the active/sleep dynamics and the contention backoscheme of SMAC protocol in multi-hop wireless sensor networks (WSNs), we model each node as a finite single server queue with server shutdown, and model each node's states as a two-dimensional continuous-time Markov chain. Based on the model, we derive the network performance in terms of average packet loss ratio, network throughput, average packet delay and average power consumption. Experiment comparisons show that the analytical results match well with the simulation results, which validates the accuracy of the analytical model. Furthermore, using the analytical model can enable us to investigate the performance tradeobetween energy efficiency and QoS requirement, and give us theoretical insight into the optimal parameters such as duty cycle, mean active period and buffer size in multi-hop wireless sensor networks. | LUO Jun JIANG LingGe HE Chen | 2010 | Science China(Information Sciences)2010，53，11： | 3 |
| 6 | A Novel Vertical Handoff Algorithm with Dynamic Weights in Wireless Heterogeneous Networks显示文摘 | Liu Xia Zhao Fangming Jiang Lingge | 2010 | China Communications2010，7，5： | 2 |
| 7 | Performance Evaluations of an IDMP-based Macro-mobility Management in Heterogeneous Wireless Networks显示文摘 | LIU Xia JIANG Lingge HE Chen | 2009 | Chinese Journal of Electronics2009，18，3： | 2 |
| 8 | Applications and challenges of low temperature plasma in pharmaceutical field显示文摘Low temperature plasma(LTP)technology has shown an outstanding application value in the pharmaceutical filed in recent ten years.This paper reviews the research advances in LTP,including its effects on enhancing or inhibiting drug activity,its combined use with drugs to treat cancers,its effects on the improvement of drug delivery system,its use in preparation of new inactivated virus vaccines,its use with mass spectrometry for rapid detection of drug quality,and the anti-tumor and sterilization effects of plasma-activated liquids.The paper also analyzes the challenges of LTP in the pharmaceutical filed,hoping to promote related research. | Lingge Gao Xingmin Shi Xili Wu | 2021 | Journal of Pharmaceutical Analysis2021，11，1： | 1 |
| 9 | Exploring the crystalline microstructure of thin films using a series of lanthanide tfifluorides as a probe 显示文摘 | LINGG L MACLEOD H | 2001 | Conference of Optical Inte(ference Coatings2001，2，： | 1 |
| 10 | A Novel Price-Based Power Control Algorithm in Cognitive Radio Networks显示文摘 | WANG Zhengqiang JIANG Lingge HE Chen | 2013 | IEEE Communications Letters2013，17，1： | 1 |
| 11 | Perfolmance analysis of vertical handoff strategy for heterogeneous overlay network显示文摘 | Hongyan Bing Cheng He Lingge Jiang | 2004 | Chinese Journal of Electlonics2004，13，4： | 1 |
| 12 | A Comparison of French and American Environmental Behaviors, Knowledge and Attitudes显示文摘 | Arbuthnot J Lingg S | 1975 | International Journal of Psychology1975，10，4： | 1 |
| 13 | Structure and properties of 3-alkoxy substituted polythiophene synthesized at low temperature 显示文摘 | Hu Xiao Xu Lingge | 2000 | Polymer2000，41，26： | 1 |
| 14 | Effect of ozonation on microbial fish pathogens,ammonia,nitrate,nitrite,and bod in simulated reuse hatchery water 显示文摘 | Colberg P J Lingg A J | 1978 | J Fish Res Board Can1978，35，10： | 1 |
| 15 | Transient emission simulation and optimization o turbocharged diesel engine显示文摘 | Lingge SUI Zhongchang LIU Yongqiang HAN Jing TIAN | 2013 | Frontiers in Energy2013，7，2： | 1 |
| 16 | Wavelet-based semi-fragile watermarking with tamper detection显示文摘 | DING Ke HE Chen JIANG Lingge WANG Hongxia | 2005 | IEICE Trans Fundamentals2005，88，3： | 1 |
| 17 | Interactions of carboxypeptidase G2 w ith 6S-leucovorin and 6R-leucovorin in vitro:implications for the application in case of methotrexate intoxications显示文摘 | Hempel G Lingg R Boos J | 2005 | Cancer Chemother Pharmacol2005，55，4： | 1 |
| 18 | Biotic and abiotic factors affecting stability of Beauveria bassiana conidia in soil 显示文摘 | Lingg A J Donaldson M D | 1981 | Invertebr Pathol1981，38，： | 1 |
| 19 | CSIT Error Analysis in TDD Systems with Estimation Delay, Noise and Pilot Interference显示文摘 | Xi Qi He Chen Jiang Lingge | 2014 | IEEE Communications Letters2014，18，2： | 1 |
| 20 | A Comparison of French and American Environmental Behaviors,Knowledge,and Attitudes显示文摘 | ARBUTHNOT J LINGG S | 1975 | International Journal of Psychology1975，10，4： | 1 |
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