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608篇 您的检索式:作者名="Liu V C"
    题名 作者 年代 出处 被引量
1Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren 2011Cell Research2011,21,10:6
2Influence of wavelength on fractionation in laser ablation ICP-MS 显示文摘Russo R E Mao X L Borisov 0 V Liu H C 2000Journal of Analytical Atomic Spectrometry2000,15,:1
3MicroRNA gene expression deregulation in human breast cancer显示文摘Iorio M V Ferracin M Liu C G 2005Cancer Res2005,65,16:1
4MicroRNA gene ex- pression deregulation in human breast caneer显示文摘Iorio M V Ferracin M Liu C G 2005Cancer Res2005,65,16:1
5Free radicals scavenging activity of mushroom polysaccharide extracts显示文摘Liu F Ooi V E C Chang S T 1997Life Sci1997,,60:1
6Metal nanoerystal memories-part I: device design and fabrication 显示文摘LIU Z LEE C NARAYANAN V 2002IEEE Electron Device Letters2002,49,9:1
7Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes显示文摘Yechoor V Liu V Espiritu C 2009Dev Cell2009,16,3:1
8Antioxidant activity of fresh apples 显示文摘EBERHARDT M V LEE C Y LIU R H 2000Nature2000,405,:1
9Expimental study of drained creep behavior of sand 显示文摘LADE P V LIU C T 1998Journal of Engineering Mechanics1998,124,8:1
10Effects of B and W alloying additions on the formation and stability of lamellar structures in two-phase y-TiAl 显示文摘Mazisaz P J Ramanujan R V Liu C T et el 1997Intermetallics1997,5,2:1
11Mechanisms of bimatefial attachment at the interface of tendon to bone显示文摘Liu Y Birman V Chen C 2011J Eng Mater Technol2011,133,01:1
12Self-generated magnetic field in an amplitude modulated laser filament in a plasma显示文摘Tripathi V K Liu C S 1994Phys Plasmas1994,1,4:1
13Observation of coherent optical information storage in an atomic medium using halted light pulses 显示文摘Liu C Dutton Z Behroozi C H and Hau L V 2001Nature( London)2001,409,:1
14MicroRNA Gene Expression Deregulation in Human Breast Cancer 显示文摘Iorio M V Ferracin M Liu C G 2005Cancer Res2005,65,16:1
15A new integrated micro-macro ap- proach to damage and fracture of composites 显示文摘Tay T Tan V B C Liu G 2006Materials Sci- ence and Engineering B: Solid-State Materials for Advanced Technology2006,132,12:1
16The effects of benzene exposure on apoptosis in epithelial lung cells: localization by tcrminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) and the irnmunocytochemical localization of apoptosis-related gene products显示文摘WEAVER C V LIU S P LU J F 2007Cell Biology and Toxicology2007,23,3:1
17Relationships be- tween hard-seededness and seed weight in mungbean( Vigna radi- ata) assessed by QTL analysis 显示文摘Humphry M E Konduri M E V Liu C J 2005Plant Breed2005,124,:1
18Functional magnetic resonance imaging aided radiation treatment planning显示文摘LIU W C SCHULDER M NARRA V 2000Med Phys2000,27,7:1
19Free radical scavenging activities of mushroom polysaccharide extracts显示文摘Liu F Ooi V E C Chang S T 1997Life Sci- ences1997,60,10:1
20Antioxidant activity of fresh apples 显示文摘Eberhardt M V Lee C Y Liu R H 2000Nature2000,405,:1
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