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| 1 | Mastoid obliteration and reconstruction techniques:A review of the literature显示文摘Objective To review the published literature related to the different obliteration and reconstruction techniques in the management of the canal wall down mastoidectomy.Methods A PubMed(Medline)and LILACS databases as well as crossed references search was performed with the following Mesh terms:“cholesteatoma”,“cholesteatoma-middle ear”,“otitis media”,“otitis media,suppurative”,“mastoiditis”,“mastoidectomy”,“canal wall down mastoidectomy”,“radical mastoidectomy”,“mastoid obliteration”and crossed references.Inclusion criteria were adult patients subject to mastoid cavity obliteration and posterior canal wall reconstruction.The technique and materials used,anatomic and functional results,complications,recurrence rates,and changes in quality of life,were analyzed.A total of 94 articles were screened,38 were included for full-text detailed review.Results Twenty-one articles fulfilled the inclusion criteria.Techniques and materials used for canal wall reconstruction,tympanoplasty,and ossiculoplasty were varied and included autologous,biosynthetic,or both.Auditory results were reported in 16 studies and were inconsistent.Three studies reported improvement in the quality of life using the GBI scale.Follow-up time ranged from 1 to 83 months.Eleven articles used imaging studies to evaluate postoperative disease recurrence.The highest recurrence rate reported for cholesteatoma after obliteration was 19%.The most frequently reported complications were retraction pockets and transient otorrhea.Conclusion Plenty of techniques combining grafts and other materials have been used to overcome mastoidectomy cavity problems.So far,it is still not possible to standardize an ideal procedure.The available level of evidence for this topic is low and limited. | Michelle Lupa Mendlovic Daniella Alejandra Monroy Llaguno Ivan Hermann Schobert Capetillo Juan Carlos Cisneros Lesser | 2021 | Journal of Otology2021，16，3： | 5 |
| 2 | Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model显示文摘 | Alcantara Llaguno S Chen J Kwon CH | 2009 | Cancer Cell2009，15，1： | 1 |
| 3 | Carbon Nanotube Com- posites for Thermal Management显示文摘 | BIERCUK MJ LLAGUNO MC | 2002 | Appl Phys Lett2002，80，： | 1 |
| 4 | Carbon nanotube composites for thermal management显示文摘 | Biercuk M J Llaguno M C Radosavljevic M | 2002 | Applied Physics Letters2002，80，15： | 1 |
| 5 | Electrical and thermal transport properties of magnetically aligned single wall carbon nanotube films显示文摘 | Hone J Llaguno M C Nemes N M | 2000 | Applied Physics Letters2000，77，5： | 1 |
| 6 | Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model显示文摘 | Sheila Alcantara Llaguno Jian Chen Chang-Hyuk Kwon Erica L. Jackson Yanjiao Li Dennis K. Burns Arturo Alvarez-Buylla Luis F. Parada | 2009 | Cancer Cell2009，，1： | 1 |
| 7 | Car- bon Nanotube Composites for Thermal Management 显示文摘 | M J Bieruck M C Llaguno M Radosalvljevic | 2002 | Appl Phys Lett2002，80，27： | 1 |
| 8 | Carbon nanotube composites for thermal management 显示文摘 | Biercuk M J Llaguno M C Radosvljevic M | 2002 | Applied Physics Letters2002，80，15： | 1 |
| 9 | Carbon nanotube composites for thermal management 显示文摘 | Biercuk M Llaguno M C Radosavljevic M | 2002 | Applied Physics Letters2002，80，15： | 1 |
| 10 | Carbon Nanotube Composites for Thermal Management 显示文摘 | Biercuk M J Llaguno M C Radosavljevic M | 2002 | Appl Phys Lett2002，80，15： | 1 |
| 11 | Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse models 显示文摘 | Lim SK Llaguno SR McKay RM | 2011 | BMB Rep2011，44，： | 1 |
| 12 | NMR characterization of humic acid fractions from different Philippine soils and sediments显示文摘 | Wershaw R L Pinckney D L Llaguno E C | 1990 | Analytica Chimica Acta1990，232，： | 1 |
| 13 | Carbon nanotube composites for thermal management 显示文摘 | Biercuk M J Llaguno M C Radosavljevic M Hyun J K Johnson A T Fischer J E | 2002 | Applied Phys cs Letters2002，80，15： | 1 |
| 14 | Glioblastoma muhiforme: a perspective on recent findings in human cancer and mouse models 显示文摘 | Lim S K Llaguno S R McKay R M eta| | 2011 | BMB Rep2011，44，3： | 1 |
| 15 | Electrical and thermal transport properties of magnetically aligned single wall carbon nanotube films显示文摘 | Hone J Llaguno M C Nemes N M | 2000 | Applied Physics Letters2000，77，： | 1 |
| 16 | Carbon nanotube composites for thermal management 显示文摘 | BIERCUK M J LLAGUNO M C RADOSAVLJEVIC M | 2002 | Appl Phys Lett2002，80，15： | 1 |
| 17 | 显示文摘 | Hone J Llaguno M C Biercuk M J | 2002 | Applied Physics A2002，74，3： | 1 |
| 18 | Carbon nanotube composites for thermal management 显示文摘 | BIERCUK M J LLAGUNO M C RADOSAVLJEVIC M | 2002 | Appl Phys Lett2002，80，15： | 1 |
| 19 | Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth显示文摘 | Kim TH Song J Alcantara Llaguno SR | 2012 | PLoS One2012，7，42： | 1 |
| 20 | Electrostatieally generated nanofibers of electronic polymers显示文摘 | OKUZAKI H LlAGUNO M | 2001 | Synth Met2001，119，： | 1 |
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