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| 1 | MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes显示文摘 | Li Y Guessous F Zhang Y Dipierro C Kefas B Johnson E Marcinkiewicz L Jiang J Yang Y Schmittgen TD Lopes B Schiff D Purow B Abounader R | 2009 | 中国神经肿瘤杂志2009,7,4: | 56 |
| 2 | Quantitative Study on Nonmetallic Inclusion Particles in Steels by Automatic Image Analysis With Extreme Values Method显示文摘The presence of nonmetallic inclusion particles which appear during steelmaking process is harmful to the properties of steels,which is mainly as a function of some aspects such as size,volume fraction,shape,and distribution of these particles.The automatic image analysis technique is one of the most important tools for the quantitative determination of these parameters.The classical Student approach and the Extreme Values Method(EVM) were used for the inclusion size and shape determination and the evaluation of distance between the inclusion particles.The results thus obtained indicated that there were significant differences in the characteristics of the inclusion particles in the analyzed products.Both methods achieved results with some differences,indicating that EVM could be used as a faster and more reliable statistical methodology. | Cássio Barbosa José Brant de Campos Jneo Lopes do Nascimento Iêda Maria Vieira Caminha | 2009 | Journal of Iron and Steel Research(International)2009,16,4: | 7 |
| 3 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021,12,10: | 5 |
| 4 | 过瘤胃蛋氨酸、赖氨酸和组氨酸对泌乳奶牛生产性能的影响显示文摘试验旨在研究饲料中单独添加或综合添加过瘤胃(RP)蛋氨酸、赖氨酸和组氨酸及可代谢蛋白(MP)对泌乳后期奶牛生产性能的影响。试验选取72头荷斯坦奶牛,随机分为6组,试验期9周。奶牛随机分配到6个试验组中,2周作为1个变量周期:MPA组,根据美国国家科学研究委员会(2001)标准,在饲料中添加调节MP到243 g·d-1;MPD组,不添加MP,MP含量低于标准量54 g·d-1;MPDM组,在MPD组的基础上加入RP蛋氨酸;MPDL组,在MPD组的基础上加入RP赖氨酸;MPDH组,在MPD组的基础上加入组氨酸;MPDMLH组,在MPD组的基础上加入RP蛋氨酸、RP赖氨酸和RP组氨酸。试验结果表明,与MPA组对比,MPD组的干物质采食量(DMI)、产奶量、乳成分(乳脂肪、乳蛋白和乳糖)及能量校正的牛乳(ECM)、ECM饲料利用效率、牛奶和血浆中的N均降低。在MPD基础上补充RP赖氨酸可使乳蛋白率、血浆中葡萄糖浓度增加,且牛奶中N元素含量有增加的趋势;补充RP组氨酸可使DMI、牛奶浓缩蛋白增加,且乳脂肪、乳蛋白和ECM显著增加;补充3种RP氨基酸时,增加了乳蛋白率,使DMI和乳脂率有增加趋势,也提高了乳脂肪、乳蛋白含量和ECM及ECM饲料利用效率。与MPA相比,MPD组牛奶中N的含量有降低趋势,且血浆中必需氨基酸(除赖氨酸和蛋氨酸)浓度均降低。补充RP赖氨酸、RP蛋氨酸和RP组氨酸提高了血浆中蛋氨酸(除MPDM组)、赖氨酸和组氨酸浓度。饲喂MPD的奶牛血红蛋白浓度降低,血浆生长素含量高于MPA组。MPD组牛奶中总饱和脂肪酸浓度有高于MPA和MPDMLH组的趋势。MPD组的多元不饱和脂肪、牛奶中奇链与支链脂肪酸含量与MPA组相比,有降低趋势。试验结果表明,对于饲料中缺乏MP的奶牛,在饲料中添加组氨酸和添加3种RP氨基酸(赖氨酸、蛋氨酸和组氨酸)均有提高牛奶产量和牛奶组分含量的可能性。 | Giallongo F Harper M T Oh J Lopes J C Lapierre H Patton R A Parys C Shinzato I Hristov A N | 2016 | 饲料博览2016,0,7: | 4 |
| 5 | 热处理对磷酸钙微晶玻璃中β-Ca_2P_2O_7晶相含量的影响显示文摘在不同条件下对摩尔组分为 3Na2 O 12TiO2 5 7CaO 2 8P2 O5玻璃进行热处理 ,研究其热处理条件与微晶玻璃的 β Ca2 P2 O7晶相含量和生物活性的关系。实验结果表明 :该组成玻璃经热处理后 ,可以获得含有 β Ca2 P2 O7,CaTi4(PO4) 6 ,NaTi2 (PO4) 3和TiP2 O7晶相的微晶玻璃 ,β Ca2 P2 O7为主晶相。随着成核温度提高和成核时间的延长 ,β Ca2 P2 O7晶相在微晶玻璃中含量增加。含较多 β Ca2 P2 O7晶相的微晶玻璃有较强的生物活性 ,主要是由于 β Ca2 P2 O7晶相有较强的促进生物活性的能力 ,因而使微晶玻璃有较强的生物活性 。 | 李延报 翁文剑 杜丕一 沈鸽 韩高荣 SANTOS J D LOPES A M | 2003 | 硅酸盐学报2003,31,7: | 4 |
| 6 | Associations of leptin gene polymorphisms with production traits in pigs 显示文摘 | De Oliveira Peixoto J Facioni Guimar?es S E Savio Lopes P | 2006 | J Anita Breed Genet2006,123,6: | 1 |
| 7 | Schistosoma mansoni: In vitro schistosomicidal activity ofpiplartine 显示文摘 | de Moraes J Nascimento C Lopes P O M V | 2011 | Exp Parasitol2011,127,2: | 1 |
| 8 | Defining control strategies for microgrids islanded operation 显示文摘 | LOPES J A P MOREIRA C L MADUREIRA A G | 2006 | IEEE Trans on Power Systems2006,21,91: | 1 |
| 9 | On the potential contributions of hybrid intelligent approaches to multicomponent robotic system development 显示文摘 | Duro R J Grana M de Lope J | 2010 | Information Sciences2010,180,14: | 1 |
| 10 | Leukocyte tyrosine kinase functions in pigment cell development显示文摘 | Lopes S S Yang X Muller J | 2008 | PloS Genetics2008,4,3: | 1 |
| 11 | Participation of doubly fed induction wind generators in system frequency regulation显示文摘 | DE ALMEIDA R G LOPES J A P | 2007 | IEEE Transactions on Power Systems2007,22,3: | 1 |
| 12 | An efficient modal control strategy for the active vibration control of a truss structure显示文摘 | Carvalhal R Lopes V J Brennan M J | 2007 | Shock and Vibration2007,14,6: | 1 |
| 13 | Participation of Doubly Fed Induction Wind Generations in System Frequency Regulation 显示文摘 | ALMEIDA R G LOPES J A | 2007 | IEEE Transactions on Power System2007,22,3: | 1 |
| 14 | Short-term memory formation and long-term memory consolidation are enhanced by cellular prion association to stress-inducible protein 1显示文摘 | Coitinho AS Lopes MH HaJ J GN | 2007 | Neurobiol Dis2007,26,1: | 1 |
| 15 | Adding protein context to the human protein -protein interaction network to reveal meaningful inter- actions显示文摘 | SCHAEFER M H LOPES T J S MAH N et at | 2013 | PLoS Comput Biol2013,9,10: | 1 |
| 16 | Correlation between serum magnesium levels and hepatic encephalopathy in imme- diate post liver transplantation period 显示文摘 | LOPES P J MEI MF GUARDIA AC | 2013 | Transplant Proc2013,45,3: | 1 |
| 17 | Linear and nonlinear dynamics of cantilevered cylinders in axial flow, Part 2 : the equation of motion 显示文摘 | J L Lopes M P Paidoussis C Semler | 2002 | Journal of Fluids and Structures2002,16,6: | 1 |
| 18 | Severe CD4 T cell-mediated immunopathology in murine schistosomiasis is de- pendent on IL-12p40 and correlates with high levels of IL-17 显示文摘 | Rutitzky L I Lopes da Rosa J R Stadecker M J | 2005 | J Immunol2005,175,6: | 1 |
| 19 | Influence of the variable-speed wind generators in transient stability margin of the conven tional generators integrated in electrical grids显示文摘 | Nunes Marcus V A Lopes J A Pecas Zurn Hans Helmut | 2004 | IEEE Trans on Energy Conversion2004,19,4: | 1 |
| 20 | 显示文摘 | Dzikh I P Lopes J M Lemos F | 1999 | Appl Catal A1999,176,2: | 1 |