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| 1 | Colonic lesion characterization in inflammatory bowel disease:A systematic review and meta-analysis显示文摘AIM To perform a systematic review and meta-analysis for the diagnostic accuracy of in vivo lesion characterization in colonic inflammatory bowel disease(IBD), using optical imaging techniques, including virtual chromoendoscopy(VCE), dye-based chromoendoscopy(DBC), magnification endoscopy and confocal laser endomicroscopy(CLE). METHODS We searched Medline, Embase and the Cochrane library. We performed a bivariate meta-analysis to calculate the pooled estimate sensitivities, specificities, positive and negative likelihood ratios(+LHR,-LHR), diagnostic odds ratios(DOR), and area under the SROC curve(AUSROC) for each technology group. A subgroup analysis was performed to investigate differences in real-time nonmagnified Kudo pit patterns(with VCE and DBC) and real-time CLE.RESULTS We included 22 studies [1491 patients; 4674 polyps, of which 539(11.5%) were neoplastic]. Real-time CLE had a pooled sensitivity of 91%(95%CI: 66%-98%), specificity of 97%(95%CI: 94%-98%), and an AUSROC of 0.98(95%CI: 0.97-0.99). Magnification endoscopy had a pooled sensitivity of 90%(95%CI: 77%-96%)and specificity of 87%(95%CI: 81%-91%). VCE had a pooled sensitivity of 86%(95%CI: 62%-95%) and specificity of 87%(95%CI: 72%-95%). DBC had a pooled sensitivity of 67%(95%CI: 44%-84%) and specificity of 86%(95%CI: 72%-94%). CONCLUSION Real-time CLE is a highly accurate technology for differentiating neoplastic from non-neoplastic lesions in patients with colonic IBD. However, most CLE studies were performed by single expert users within tertiary centres, potentially confounding these results. | Richard Lord Nicholas E Burr Noor Mohammed Venkataraman Subramanian | 2018 | World Journal of Gastroenterology2018，24，10： | 2 |
| 2 | Percutaneous sclerotherapy for lymphatic malformations:a retrospective analysis of patient-evaluated improvement显示文摘 | Alomari A I Karian V E Lord D J | 2006 | J Vasc Interv Radiol2006，17，10： | 1 |
| 3 | Blood pressure changes on upright tilting predict falls in older people 显示文摘 | Heitterachi E Lord SR Meyerkort P | 2002 | Age Ageing2002，31，3： | 1 |
| 4 | Agricultural nitrogen balance and water quality in the UK显示文摘 | LORD E I ANTHONY S G GOODLASS G | 2002 | Soil Use and Management2002，18，4： | 1 |
| 5 | Dynamic characteristics of a base isolated building from ambient vibration measurements and low level earthquake shaking 显示文摘 | Ventura C E Liam F W D Lord J F | 2003 | Soil Dynamics and Earthquake Engineering2003，23，4： | 1 |
| 6 | Mangy mutt or furry friend?Anthropomorphism promotes animal welfare显示文摘 | Butterfield M E Hill S E Lord C G | 2012 | Journal of Experimental Social Psychology2012，48，4： | 1 |
| 7 | Dynamic characteristics of a base isolated building from ambient vibration measurements and low level earthquake shaking显示文摘 | Ventura C E Liam Finn W D Lord J F | 2003 | Soil Dynamics and Earthquake Engineering2003，23，： | 1 |
| 8 | Modulation of peroxisome proliferator-activated re-ceptor delta and gamma transcripts in swine endome-trial tissue during early gestation显示文摘 | LORD E MURPHY B D DESMARAIS J A | 2006 | Reproduction2006，131，5： | 1 |
| 9 | Utilizing RNA interference to enhance cancer drug discovery显示文摘 | Iorns E Lord C J Turner N | 2007 | Nat Rev Drug Discov2007，6，7： | 1 |
| 10 | A photoactivatable push-pull fluorophore for single-molecule imaging in live cells显示文摘 | Lord S J Conley N R Lee H L D Samuel R Liu N Twieg R J Moerner W E | | 0，，29： | 1 |
| 11 | The gona- dotrophin-releasing hormone receptor maps to sheep chro- mosome 6 outside of the region of the FecB locus 显示文摘 | Montgomery G W Penty J M Lord E A | 1995 | Mammalian Genome: Official Journal of the International Mammalian Genome Society1995，6，6： | 1 |
| 12 | Sampling technique to discriminate the different tissue layers of growing antler tips for gene discovery显示文摘 | Li C Clark D E Lord E A | 2002 | Anat Rec2002，268，2： | 1 |
| 13 | Sampling technique to discriminate the different tissue layers of growing antler tips for gene discovery显示文摘 | Li C Clark D E Lord E A | 2002 | Anat Rec2002，268，2： | 1 |
| 14 | Emer- ging Methods for Geomembrane Seaming 显示文摘 | LORD A E HALSEY H KOERNER R M | 1990 | Geotextiles and Geomembranes1990，9，46： | 1 |
| 15 | Interrater reliability using Modified Norton Scale, Pressure Ulcer Card, Short Form-Mini Nutritional Assessment by reg- istered and enrolled nurses in clinical praetiee显示文摘 | Baath · C Hall- Lord · ML Idvall - E | 2008 | Journal of Clinical Nursing2008，17，5： | 1 |
| 16 | Calcium levels increase in the lily stylar transmitting tract after pollination显示文摘 | ZHAO J YANG H Y LORD E M | 2004 | Sex Plant Reprod2004，16，： | 1 |
| 17 | Profiles of strontium and barium in Mercenaria mercenaria and Spisula solidissima shells 显示文摘 | Stecher H A Krantz D E Lord C J | 1996 | Geochimica Et Cosmoehimica Acta1996，60，18： | 1 |
| 18 | The de velopmental neurobiology of autism spectrum disorder显示文摘 | DiCicco-Bloom E Lord C Zwaigenbaum L | 2006 | J Neuroscl2006，26，26： | 1 |
| 19 | The booroola fecundity (FecB) gene maps to sheep chromosome 6显示文摘 | Montgomery G W Lord E A Penty J M | 1994 | Genomics1994，22，1： | 1 |
| 20 | Identification of Booroola carries using microsatellite markers显示文摘 | Lord E A Davis G H Dodds K G | 1998 | Wool Technology and Sheep Breeding1998，46，： | 1 |
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