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281篇 您的检索式:作者名="Lowe H J"
    题名 作者 年代 出处 被引量
1胚胎巨噬细胞和小胶质细胞消融调控小鼠胚胎背根神经节感觉神经元的发育显示文摘众所周知,小胶质细胞可以调节中枢神经系统发育的一些方面。在第11.5天的小鼠胚胎中的小胶质细胞定殖脊髓时,它们与背根神经节感觉神经元(SN)的生长中心轴突相互作用,这表明它们可能在SN发育中发挥一定功能。为了解决这个问题,我们使用缺乏胚胎巨噬细胞(PU.1敲除小鼠)和免疫细胞消融的小鼠胚胎分析胚胎巨噬细胞消融对SNs早期发育的影响。我们发现,除小胶质细胞外,胚胎巨噬细胞还与来自第11.5天的小鼠胚胎的原肌球蛋白受体激酶(Trk)C+感觉神经元,TrkB+感觉神经元和TrkA+感觉神经元外周神经突产生交联。免疫细胞剥夺会导致第11.5天的小鼠胚胎的TrkC+感觉神经元和TrkB+感觉神经元初始数量的减少,这与其发育细胞死亡(DCD)的改变有关联的可能性较小,因为其后在第12.5天的胚胎中的数量有短暂增加。在分析的发育期(第11.5~15.5天),它也导致TrkA+感觉神经元数量减少,尽管我们没有观察到他们的DCD有任何变化。与神经元祖细胞可能存在一致性的脑脂肪酸结合蛋白(BFABP-)阴性细胞的增殖在第11.5天的胚胎中增加,而它们的增殖在第12.5天的胚胎减少,这可部分解释从11.5 d观察到的SN亚型产生的改变。此外,我们观察到在缺乏胚胎巨噬细胞的情况下神经胶质细胞祖细胞(BFABP+细胞)增殖的改变。我们的数据表明,胚胎巨噬细胞和小胶质细胞消融调控SN的发育。Angelim MKSC Maia LMSS Mouffle C Ginhoux F Low D Amancio-Dos-Santos A Makhoul J Le Corronc H Mangin JM Legendre P 聂昊(编译) 2018神经损伤与功能重建2018,13,9:2
2Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats 显示文摘Pushparaj P N Low H K Manikandan J 2007J Ethnopharmaeol2007,111,2:1
3Thermal cycling analysis of flip-chip solder joint reliability 显示文摘Pang J H L Chong D Y R Low T H 2001Components and Packaging Technologies2001,24,4:1
4Development and practice of a glasshouse screen- ing technique for resistance of wheat to the aphid Sitobion avenae显示文摘Lowe H J B 1984Annals of Applied Biology1984,104,2:1
5Optimistic Synchronization in HLA-based Distributed Simulation 显示文摘X Wang S J Turner M Y H Low 2005Simulation (S0037-5497)2005,81,4:1
6The relative importance of non-sea-salt sulphate and sea-salt aerosol to the marine cloud condensation nuclei population:Animproved multi-component aerosol-cloud droplet parametrization显示文摘O'Dowd C D Lowe J A Smith M H 1999Quart J Roy Meteor Soc1999,125,556:1
7Advanced g1ycation end-products (AGEs) and functiona-lity of reverse cholesterol transport in patients with type 2 diabetes and in mouse models 显示文摘Low H Hoang A Forbes J 2012Diabetologia2012,55,9:1
8Heuristic solutions to multidepot location-routing problem显示文摘Wu T H Low C Bai J W 2002Computers&Operations Research2002,29,:1
9Zero duality gap in optimal power flow problem显示文摘Lavaei J Low S H 0,,1:1
10Efficient system reliability analysis illustrated for a retaining wall and a soil slope显示文摘LOW B K ZHANG J TANG W H 2011Computers and Geotechnics2011,38,2:1
11The application of DNA methods to timber tracking and origin verification显示文摘Lowe A J Cross H 13 2011IAWA Journal2011,32,2:1
12In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes 显示文摘Lachmann H J Lowe P Felix SD 2009J Exp Med2009,206,:1
13Analysis of food oligosaccharides using MALDI-MS:quantification of fructooligosaccharides显示文摘WANG J SPORNS P LOW N H 1999Journal of Agricultural and Food Chemistry1999,47,4:1
14Video parsing and browsing using compressed data 显示文摘Zhang H J Low C Y Smoliar S W 1995Multimedia Tools and Applications1995,1,1:1
15Internet Congestion Control显示文摘Low S H Paganini F Doyle J 2002IEEE Control System Magazine2002,22,1:1
16Modeling 2-D spatial varia-tion in slope reliability analysis using interpolated auto-correlations 显示文摘Ji J Liao H J Low B K 2012Computers and Geotechnics2012,40,:1
17Strategy for the Instantaneous Torque Control of Permanent-magnet Brushless DC Drives显示文摘Low T S Tseng K J Lee T H 1990IEE Proceedings1990,137,6:1
18Primary structure of thymosin beta 12, a new member of the beta- thymosin family isolated from perch liver 显示文摘Low T L Liu D T Jou J H 1992Arch Biochem Biophys1992,293,1:1
19The roles of oxidative stress and antioxidant treatment In experimental diabetic neuropathy显示文摘Low P A Nickander K K Tritschler H J 1997Diabetes1997,3,2:1
20Heuristic solutions to multi-depot location-routing problems显示文摘Wu T H Low C Bai J W 2002Computers and Operations Research2002,9,10:1
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