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| 1 | 多形性黄色瘤型星形细胞瘤:自然病史和长期随访显示文摘作者回顾性研究74例多形性黄色瘤型星形细胞瘤(PXA)组织学问变特征和BRAFV600E突变的预后意义。患者平均诊断年龄21.5岁,包括31例儿童和43例成人,随访中位时间为7.6年。间变特征(PXA—AF)定义为核分裂指数≥5个/10HPF和(或)伴有坏死,共有33例。作者将其中60例进行免疫组化和(或)分子分析,发现其中39例BRAFV600E突变,且这39例IDH1(R132H)均为阴性。 | Ida C M Rodriguez F J Burger P C 李晓玲 王行富 | 2015 | 临床与实验病理学杂志2015，31，11： | 9 |
| 2 | Predictors of spine deformity progression in adolescent idiopathic scoliosis: A systematic review with meta-analysis显示文摘AIM: To evaluate published data on the predictors of progressive adolescent idiopathic scoliosis(AIS) in order to evaluate their efficacy and level of evidence. METHODS: Selection criteria:(1) study design: randomized controlled clinical trials, prospective cohort studies and case series, retrospective comparative and none comparative studies;(2) participants: adolescents with AIS aged from 10 to 20 years; and(3) treatment: observation, bracing, and other. Search method: Ovid MEDLINE, Embase, the Cochrane Library, Pub Medand patent data bases. All years through August 2014 were included. Data were collected that showed an association between the studied characteristics and the progression of AIS or the severity of the spine deformity. Odds ratio(OR), sensitivity, specificity, positive and negative predictive values were also collected. A metaanalysis was performed to evaluate the pooled OR and predictive values, if more than 1 study presented a result. The GRADE approach was applied to evaluate the level of evidence.RESULTS: The review included 25 studies. All studies showed statistically significant or borderline association between severity or progression of AIS with the following characteristics:(1) An increase of the Cobb angle or axial rotation during brace treatment;(2) decrease of the rib-vertebral angle at the apical level of the convex side during brace treatment;(3) initial Cobb angle severity(> 25o);(4) osteopenia;(5) patient age < 13 years at diagnosis;(6) premenarche status;(7) skeletal immaturity;(8) thoracic deformity;(9) brain stem vestibular dysfunction; and(10) multiple indices combining radiographic, demographic, and physiologic characteristics. Single nucleotide polymorphisms of the following genes:(1) calmodulin 1;(2) estrogen receptor 1;(3) tryptophan hydroxylase 1;(3) insulin-like growth factor 1;(5) neurotrophin 3;(6) interleukin-17 receptor C;(7) melatonin receptor 1B, and(8) Scoli Score test. Other predictors included:(1) impairment of melatonin signaling in osteoblasts and peripheral blood mononuclear cells(PBMC);(2) G-protein signaling dysfunction in PBMC; and(3) the level of platelet calmodulin. However, predictive values of all these findings were limited, and the levels of evidence were low. The pooled result of brace treatment outcomes demonstrated that around 27% of patents with AIS experienced exacerbation of the spine deformity during or after brace treatment, and 15% required surgical correction. However, the level of evidence is also low due to the limitations of the included studies.CONCLUSION: This review did not reveal any methods for the prediction of progression in AIS that could be recommended for clinical use as diagnostic criteria. | Andriy Noshchenko Lilian Hoffecker Emily M Lindley Evalina L Burger Christopher MJ Cain Vikas V Patel Andrew P Bradford | 2015 | World Journal of Orthopedics2015，6，7： | 4 |
| 3 | Prediction of progression of non-muscle-invasive bladder cancer by WHO 1973 and 2004 grading and by FGFR3 mutation status: A prospective study显示文摘 | Burger M Madelon NM Johanna MM | 2008 | Eur Urol2008，54，4： | 1 |
| 4 | Sensors based on piezoelectric resonators 显示文摘 | Bens E Groschl M Burger W | 1995 | Sens Actuators B1995，48，： | 1 |
| 5 | Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia显示文摘 | Esteller M Hamilton SR Burger PC | 1999 | Cancer Res1999，59，4： | 1 |
| 6 | Inactivation of theDNA repair gene O6-methylguanine DNA methyltransferase bypromoter hypermethylation is a common event in primary humanneoplasia显示文摘 | Esteller M Hamilton SR Burger PC | 1999 | Cancer Res1999，59，4： | 1 |
| 7 | Spatial and temporal distribution of trace metals in sediments from the Scheldt Estuary, south - west Netherlands 显示文摘 | ZWOLSMAN J J G VANECK O T M BURGER O | 1996 | Coastal land Shelf Science1996，，43： | 1 |
| 8 | The predictive validity of general movements--a systematic revicw显示文摘 | Burger M Louw QA | 2009 | Eur J Paediatr Neurol2009，13，5： | 1 |
| 9 | Unravelling the tumor-suppres- sive functions of FOXO proteins 显示文摘 | Dansen T B Burgering B M | 2008 | Trends Cell Biol2008，18，9： | 1 |
| 10 | Should I stay or should Igo: beta-catenin decides under stress 显示文摘 | Hoogeboom D Burgering B M | 2009 | BiochimBiophys Acta2009，1796，2： | 1 |
| 11 | The subspace Gaussian mixture model: A structured model for speech recognition 显示文摘 | Povey D Burger L Agarwal M | 2011 | Comput Speech Lang2011，25，2： | 1 |
| 12 | Single - particle EM reveals plasticity of interactions between the adenovirus penton base and integrin aV^3显示文摘 | Veesler D Cupelli K Burger M | 2014 | Proc Natl Acad Sci USA2014，111，24： | 1 |
| 13 | p150 expression and its prognostic value in squamous-cell carcinoma of esophagus显示文摘 | Chen G Burger M M | 1999 | Int J Cancer1999，84，2： | 1 |
| 14 | Com- plications of axial lumbar interbody fusion 显示文摘 | LINDLEY E M MCCULLOUGH M A BURGER E L | 2011 | J Neurosurg- Spine2011，3，3： | 1 |
| 15 | Changes in transcrption within the CA1 field of the hippocampus areassociated with age-related spatial learning impairments显示文摘 | Burger C López M C Feller J A | 2007 | Neurobiol Learn Mem2007，87，1： | 1 |
| 16 | Elastic stable intramedullary nailing of mid clavicular fractures in adults:32patients followed for 1 ~ 5 years显示文摘 | Mueiler M Burger C Florczyk A | | 0，，03： | 1 |
| 17 | Statistical detection and analysis of mismatch negativity derived by a multi -deviant design from normal hearing children 显示文摘 | Petermann M Kummer P Burger M | 2009 | Hearing Research2009，247，2： | 1 |
| 18 | A novel member of human tissue inhibitor of metalloproteinase (TIMP) gene family is regulated during GI progression,mitogenic stimulatin,differentiation and senescence显示文摘 | Burger C Muller R | 1994 | J Biol Chem1994，269，18： | 1 |
| 19 | Mental disorders among persions with heart disease-results from world 显示文摘 | Ormel J Von Korff M Burger H | 2007 | Gen Hosp Psychiatry2007，29，4： | 1 |
| 20 | Central nervous system atypical teratoid/rhabdoid tumor:results of therapy in children enrolled in a registry显示文摘 | Hilden J M Meerbaum S Burger P | 2004 | J Clin Oncol2004，22，14： | 1 |
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