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| 1 | Probiotic effects on intestinal fermentation patterns in patients with irritable bowel syndrome显示文摘AIM: To determine whether Lactobacillus casei strain Shirota (Yakult ) can alter small intestinal bacterial overgrowth (SIBO), as tested by the lactulose breath test, and whether this is associated with changes in symptoms in irritable bowel syndrome (IBS). METHODS: 18 patients with IBS (Rome Ⅱ criteria), who showed an early rise in breath hydrogen with lactulose (ERBHAL), consumed 65 mL of Yakult daily for 6 wk. Lactulose breath test was repeated at the end of the treatment period. Symptoms were recorded daily using a 10 cm visual analogue scale. RESULTS: 14 patients completed the study, 9 (64%) had reversal of ERBHAL, with the median time of f irst rise in breath hydrogen increasing from 45 to 75 min (P = 0.03). There was no signifi cant improvement in the symptom score with probiotic therapy, except for wind (P=0.04). Patients commencing with at least moderate symptoms and who no longer had ERBHAL at the end of treatment, showed improvement in the overall symptoms scores [median fi nal score 5.3 (IQR3.9-5.9), 55% reduction; n=6] to a greater extent than those who had had persisting ERBHAL [final score 6.9 (5.0-7.0), 12% reduction; n = 5; P = 0.18]. CONCLUSION: Yakult is effective in altering fermentation patterns in the small bowel, consistent with reducing SIBO. The loss of ERBHAL was associated with reduced symptoms. The true interpretation of these fi ndings awaits a randomised, controlled trial. | Jacqueline S Barrett Kim EK Canale Richard B Gearry Peter M Irving Peter R Gibson | 2008 | World Journal of Gastroenterology2008，14，32： | 16 |
| 2 | An algorithm for the allocation of distribution system demand and energy loss显示文摘 | MACQUEEN C N IRVING M R | 1996 | IEEE Transactions on Power System1996，11，2： | 1 |
| 3 | NGX-4010,a eapsa- icin 8 dermal patch, administered alone or in combina- tion with systemic neuropathic pain medications, reduces pain in patients with postherpetic neuralgia 显示文摘 | Irving G Baekonja M Rauck R | 2012 | Clin J Pain2012，28，2： | 1 |
| 4 | Phylogeny of the serpin su- perfamily: implications of patterns of amino acid conservation for structure and function显示文摘 | Irving J A Pike R N Lesk A M | 2000 | Genome Res2000，10，12： | 1 |
| 5 | Robust state estimator based on maximum constraints satisfaction of uncertain measurement显示文摘 | AL-OTHMAN A K IRVING M R | 2007 | Measurement2007，40，3： | 1 |
| 6 | An algorithm for the allocation of distribution systemdemand and energy losses显示文摘 | Macqueen C N, Irving M R | 1996 | IEEE Transactions on Power Systems1996，11，1： | 1 |
| 7 | Combined active and reactive dispatch-Part 1: problem formulation and solution algorithm显示文摘 | Chebbo A M Irving M R | 1995 | IEE Proc Generation Transmission Distribution1995，142，4： | 1 |
| 8 | Robust state estimation using mixed integer programming显示文摘 | IRVING M R | 2008 | IEEE Trans on Power Systems2008，23，3： | 1 |
| 9 | Investigating the Cost - effectiveness of Videotelephone Based Support for Newly Diagnosed Paediatric Oncology Patients and Their Families : design of a randomised controlled trial 显示文摘 | Bensink M Wootton R Irving H | 2007 | BMC Health Services Research2007，，7： | 1 |
| 10 | Robust algorithm for generalized state estlmation显示文摘 | IRVING M R | 2009 | IEEE Trans on Power Systems2009，24，4： | 1 |
| 11 | Transmission loss allocation through a modified Y-bus显示文摘 | Daniel J S Salgado R S Irving M R | 2005 | lEE Proceedings-Generation Transmission andDistribution2005，152，2： | 1 |
| 12 | Activation of 5-HT3 receptors in the rat and mouse intestinal tract:a comparative study显示文摘 | Chetty N Irving H R Coupar I M | 2006 | Br J Pharmacol2006，148，7： | 1 |
| 13 | A genetic algorithm modeling framework and solution technique for short term optimal hydrothermal seheduling 显示文摘 | Orero S O Irving M R | 1998 | IEEE Trans on Power Systems1998，13，2： | 1 |
| 14 | Influence of dose of N-methyl -N-nitrosourea on the induction of urinary bladder cancer in rats显示文摘 | Irving C C Cox R Murphy W M | 1979 | Cancer letter1979，8，1： | 1 |
| 15 | Large scale unit commitment using a hybrid genetic algorithm显示文摘 | Orero S O Irving M R | 1997 | Electrical Power & Energy Systems1997，19，1： | 1 |
| 16 | Real-Time Power System Simulator显示文摘 | Rafian M Sterling M J H Irving M R | 1987 | IEEE Proceedings1987，134，3： | 1 |
| 17 | A genetic algorithm modelling framework and solution technique forshort term optimal hydrothermal scheduling显示文摘 | Orero S O Irving M R | 1998 | IEEE Trans on Power Systems1998，13，2： | 1 |
| 18 | A genetic algorithm modelling framework and solution technique for short term optimal hydrothermal scheduling显示文摘 | Orero S O Irving M R | 1998 | IEEE Transactions on Power Systems1998，13，2： | 1 |
| 19 | Operation of hybrid windturbine compressed-air system for connection to electric grid networks and cogeneration显示文摘 | Ben M E Paul L Irving R | 2003 | Wind Engineering2003，27，6： | 1 |
| 20 | Expression and characterization of infectious bursal disease virus polyprotein in yeast 显示文摘 | Jagadish M N Vaughan P R Irving R A | 1990 | Gene1990，95，： | 1 |
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